The N-terminal capping propensities of the D-helix modulate the allosteric activation of the Escherichia coli cAMP receptor protein

Journal of Biological Chemistry

Volumn 287, Issue 47, 2012, Pages 39402-39411

  Yu, Shaoning ^a,b   Maillard, Rodrigo A ^a,c   Gribenko, Alexey V ^a,d   Lee, J Ching ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; ESCHERICHIA COLI;

ALLOSTERIC ACTIVATION; ALLOSTERY; BINDING DOMAIN; CAMP RECEPTOR PROTEINS; COOPERATIVITY; N-TERMINALS; QUANTITATIVE CHARACTERIZATION; STRUCTURAL MODELING;

CHEMICAL ACTIVATION;

CYCLIC AMP RECEPTOR; ESCHERICHIA COLI PROTEIN; CRP PROTEIN, E COLI; CYCLIC AMP; CYCLIC AMP BINDING PROTEIN;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA HELIX; ISOMERIZATION; MOLECULAR DYNAMICS; MUTANT; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; RECEPTOR AFFINITY; RECEPTOR BINDING; RESIDUE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THERMODYNAMICS; CHEMISTRY; ESCHERICHIA COLI; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ALLOSTERIC REGULATION; CYCLIC AMP; CYCLIC AMP RECEPTOR PROTEIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84873946911     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.404806     Document Type: Article

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