Molecular origin of constant m-values, denatured state collapse, and residue-dependent transition midpoints in globular proteins

Biochemistry

Volumn 48, Issue 17, 2009, Pages 3743-3754

  O'Brien, Edward P ^a,b   Brooks, Bernard R ^b   Thirumalai, D ^a  

^a Bldg 142   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COARSE-GRAINED; COLLAPSE TRANSITIONS; COMPACT STRUCTURES; DENATURANT CONCENTRATION; DENATURED STATE; GLOBULAR PROTEINS; MOLECULAR ORIGINS; MOLECULAR SIMULATIONS; MOLECULAR TRANSFER; NATIVE STATE; RADIUS OF GYRATION; RESIDUAL STRUCTURE; SECONDARY STRUCTURE ELEMENTS; SIDE CHAINS; SINGLE MOLECULE EXPERIMENTS; SOLVENT INTERACTIONS; STRUCTURAL ELEMENTS; SURFACE AREA; TOTAL SURFACE AREA; TRANSFER MODELS; TRANSITION MIDPOINT; TWO-STATE FOLDERS;

AMINES; AMINO ACIDS; DENATURATION; EXPERIMENTS; ORGANIC ACIDS; UREA;

PROTEIN FOLDING;

GLOBULAR PROTEIN;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HYDROPHOBICITY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SIMULATION;

BINDING SITES, ANTIBODY; CATHEPSINS; COMPUTER SIMULATION; CYSTEINE ENDOPEPTIDASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMMUNOGLOBULIN G; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SURFACE PROPERTIES; THERMODYNAMICS;

EID: 66049114131     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8021119     Document Type: Article

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