Improved production of secreted heterologous enzyme in Bacillus subtilis strain MGB874 via modification of glutamate metabolism and growth conditions

Microbial Cell Factories

Volumn 12, Issue 1, 2013, Pages

  Manabe, Kenji ^a,b   Kageyama, Yasushi ^a   Morimoto, Takuya ^a   Shimizu, Eri ^a   Takahashi, Hiroki ^c   Kanaya, Shigehiko ^b   Ara, Katsutoshi ^a   Ozaki, Katsuya ^a   Ogasawara, Naotake ^b  

^a KAO CORPORATION   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

Bacillus subtilis; Genome reduction; Glutamate metabolism; Protein secretion

Indexed keywords

2 ISOPROPYLMALATE SYNTHASE; 2 OXOGLUTARIC ACID; ALKALINE CELLULASE; AMYLASE; ASPARAGINASE; BACTERIAL ENZYME; GLUTAMIC ACID; NITROGEN; PHOSPHOGLYCERATE DEHYDROGENASE; SERINE PROTEINASE; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; BACTERIUM CULTURE; BATCH FERMENTATION; ENZYME RELEASE; NONHUMAN; PH;

AMMONIA; BACILLUS SUBTILIS; CELLULASES; CITRIC ACID CYCLE; DOWN-REGULATION; GENE EXPRESSION PROFILING; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; KETOGLUTARIC ACIDS; SEQUENCE DELETION;

BACILLUS SUBTILIS;

EID: 84873938424     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-12-18     Document Type: Article

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