Mesenchymal Stem Cell-Cardiomyocyte Interactions under Defined Contact Modes on Laser-Patterned Biochips

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Ma, Zhen ^a,f   Yang, Huaxiao ^a   Liu, Honghai ^a   Xu, Meifeng ^b   Runyan, Raymond B ^c   Eisenberg, Carol A ^d   Markwald, Roger R ^e   Borg, Thomas K ^e   Gao, Bruce Z ^a  

^a AMRL   (United States)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d NEW YORK MEDICAL COLLEGE   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f University of California at Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BIOCHIP; CELL CONTACT; CELL INTERACTION; CELL TRANSPORT; EQUIPMENT DESIGN; HEART MUSCLE CELL; MESENCHYMAL STEM CELL; MITOCHONDRION; NEWBORN; NONHUMAN; RAT; STIMULUS RESPONSE;

ANIMALS; ANIMALS, NEWBORN; CELL COMMUNICATION; CELL FUSION; CELL MEMBRANE; CELL TRACKING; CELLS, CULTURED; COCULTURE TECHNIQUES; FLUORESCENT DYES; IMMUNOHISTOCHEMISTRY; INDOLES; INTERCELLULAR JUNCTIONS; LASERS; MESENCHYMAL STROMAL CELLS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MYOCYTES, CARDIAC; RATS; REPRODUCIBILITY OF RESULTS; SINGLE-CELL ANALYSIS;

EID: 84873908958     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056554     Document Type: Article

References (48)

1. Oettgen P, Boyle AJ, Schulman SP, Hare JM, (2006) Cardiac stem cell therapy. Need for optimization of efficiency and safety monitoring. Circulation 114: 353-358.
2. De Angelis A, Piegari E, Cappetta D, Marino L, Filippelli A, et al. (2010) Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function. Circulation 121: 276-292.
3. Hosoda T, D'Amario D, Cabral-Da-Silva MC, Zheng H, Padin-Iruegas ME, et al. (2009) Clonality of mouse and human cardiomyogenesis in vivo. Proc Natl Acad Sci U S A 106: 17169-17174.
4. Orlic D, Kajstura J, Chimenti S, Bodine DM, Leri A, et al. (2003) Bone marrow stem cells regenerate infarcted myocardium. Pediatr Transplant 7: 86-88.
5. Abarbanell AM, Coffey AC, Fehrenbacher JW, Beckman DJ, Herrmann LJ, et al. (2009) Proinflamatory cytokine effects on mesenchymal stem cell therapy for the ischemic heart. Ann Thorac Surg 88: 1036-1043.
6. Rogers TB, Pati S, Gaa S, Riley D, Khakoo AY, et al. (2011) Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes. J Mol Cell Cardiol 50: 346-356.
7. Wang T, Xu Z, Jiang W, Ma A, (2006) Cell-to-cell contact induced mesenchymal stem cell to differentiate into cardiomyocyte and smooth muscle cell. Int J Cardiol 109: 74-81.
8. Xu M, Wani M, Dai YS, Wang J, Yan M, et al. (2004) Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes. Circulation 110: 2658-2665.
9. Pijnappels DA, Schalij MJ, Ramkisoensing AA, van Tuyn J, de Vries AA, et al. (2008) Forced alignment of mesenchymal stem cells undergoing cardiomyogenic differentiation affects functional integration with cardiomyocyte cultures. Circ Res 103: 167-176.
10. Valarmathi MT, Fuseler JW, Goodwin RL, Davis JM, Potts JD, (2011) The mechanical coupling of adult marrow stromal stem cells during cardiac regeneration assessed in a 2D co-culture model. Biomaterials 32: 2834-2850.
11. Cselenyak A, Pankotai E, Horvath EM, Kiss L, Lacza Z, (2010) Mesenchymal stem cells rescue cardiomyoblasts from cell death in an in vitro ischemic model via direct cell-to-cell connections. BMC Cell Biol 11: 29.
12. Pedrotty DM, Klinger RY, Badie N, Hinds S, Kardashian A, et al. (2008) Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay. Am J Physiol Heart Circ Physiol 295: H390-400.
13. Avitabile D, Crespi A, Brioschi C, Parente V, Toietta G, (2011) Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process. Am J Physiol Heart Circ Physiol 300: H1875-1884.
14. Song YH, Pinkernell K, Alt E, (2011) Stem cell induced cardiac regeneration: fusion/mitochondria exchange and/or transdifferetiation? Cell Cycle 10: 2281-2286.
15. Plotnikov EY, Khryapenkova TG, Vasileva AK, Marey MV, Galkina SI, et al. (2008) Cell-to-cell cross-talk between mesenchymal stem cells and cardiomyocytes in co-culture. J Cell Mol Med 12: 1622-1631.
16. Ma Z, Pirlo RK, Wan Q, Yun JX, Yuan X, et al. (2011) Laser-guidance-based cell deposition microscope for heterotypic single-cell micropatterning. Biofabrication 3: 034107.
17. Liu H, Qin W, Shao Y, Ma Z, Ye T, et al. (2011) Myofibrillogenesis in live neonatal cardiomyocytes observed with hybrid two-photon excitation fluorescence-second harmonic generation microscopy. J Biomed Opt 16: 126012.
18. Ma Z, Liu Q, Liu H, Yang H, Yun JX, et al. (2012) Cardiogenic regulation of stem-cell electrical property in a laser-patterned biochip. Cell Mol Bioeng 5: 327-336.
19. Ma Z, Liu Q, Liu H, Yang H, Yun JX, et al. (2012) Laser-patterned stem-cell bridges in a cardiac muscle model for on-chip electrical conductivity analyses. Lab Chip 12: 566-573.
20. Pirlo RK, Ma Z, Sweeney A, Liu H, Yun JX, et al. (2011) Laser-guided cell micropatterning system. Rev Sci Instrum 82: 013708.
21. Ma Z, Gao BZ, (2012) Quantitatively analyzing the protective effect of mesenchymal stem cells on cardiomyocytes in single-cell biochips. Biotechnol Lett 34: 1385-1391.
22. Lindstrom S, Andersson-Svahn H, (2011) Miniaturization of biological assays - overview on microwell devices for single-cell analyses. Biochim Biophys Acta 1810: 308-316.
23. Alvarez-Dolado M, Martinez-Losa M, (2011) Cell fusion and tissue regeneration. Adv Exp Med Biol 713: 161-175.
24. Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, Fike JR, Lee HO, et al. (2003) Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425: 968-973.
25. Alvarez-Dolado M, (2007) Cell fusion: biological perspectives and potential for regenerative medicine. Front Biosci 12: 1-12.
26. Nygren JM, Jovinge S, Breitbach M, Sawen P, Roll W, et al. (2004) Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med 10: 494-501.
27. Driesen RB, Dispersyn GD, Verheyen FK, van den Eijnde SM, Hofstra L, et al. (2005) Partial cell fusion: a newly recognized type of communication between dedifferentiation cardiomyocytes and fibroblasts. Cardiovasc Res 68: 37-46.
28. Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH, (2004) Nanotubular highways for intercellular organelle transport. Science 303: 1007-1010.
29. Gerdes HH, Bukoreshtliev NV, Barroso JF, (2007) Tunneling nanotubes: a new route for exchange of components between animal cells. FEBS Lett 581: 2194-2201.
30. Wang X, Gerdes HH, (2012) Long-distance electrical coupling via tunneling nanotubes. Biochim Biophys Acta 8: 2082-2086.
31. Wang X, Veruki ML, Bukoreshtliev NV, Hartveit E, Gerdes HH, (2010) Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels. Proc Natl Acad Sci U S A 107: 17194-17199.
32. Bereiter-Hahn J, (1990) Behavior of mitochondria in the living cell. Int Rev Cytol 122: 1-63.
33. Garbade J, Schubert A, Rastan AJ, Lenz D, Walther T, et al. (2005) Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model. Eur J Cardiothorac Surg 28: 685-691.
34. Kajstura J, Rota M, Whang B, Cascapera S, Hosoda T, et al. (2005) Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res 96: 127-137.
35. Zhang S, Wang D, Estrov Z, Raj S, Willerson JT, et al. (2004) Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo. Circulation 110: 3803-3807.
36. He XQ, Chen MS, Li SH, Liu SM, Zhong Y, et al. (2010) Co-culture with cardiomyocytes enhanced the myogenic conversion of mesenchymal stromal cells in a dose-dependent manner. Mol Cell Biochem 339: 89-98.
37. Prochiantz A, Joliot A, (2003) Can transcription factors function as cell-cell signaling molecules? Nat Rev Mol Cell Biol 4: 814-819.
38. Acquistapace A, Bru T, Lesault PF, Figeac F, Coudert AE, et al. (2011) Human mesenchymal stem cells reprogram adult cardiomyocytes toward a progenitor-like state through partial cell fusion and mitochondria transfer. Stem Cells 29: 812-824.
39. Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, et al. (2010) Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142: 375-86.
40. Qian L, Huang Y, Spencer IC, Foley A, Vedantham V, et al. (2012) In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 485: 593-8.
41. Onfelt B, Nedvetzki S, Benninger RK, Purbhoo MA, Sowinski S, et al. (2006) Structurally distinct membrane nanotube between human macrophages support long-distance vesicular traffic or surfing of bacteria. J Immunol 177: 8476-8483.
42. He K, Luo W, Zhang Y, Liu F, Liu D, et al. (2010) Intercellular transportation of quantum dots mediated by membrane nanotubes. ACS Nano 4: 3015-3022.
43. He K, Shi X, Zhang X, Dang S, Ma X, et al. (2011) Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes. Cardiovasc Res 92: 39-47.
44. Abel MP, Riese SR, Schlicker O, Bukoreshtliev NV, Gerdes HH, et al. (2011) Microstructured platforms to study nanotube-mediated long-distance cell-to-cell connections. Biointerphases 6: 22-31.
45. Biswas G, Adebanjo OA, Freedman BD, Anandatheerthavarada HK, Vijayasarathy C, et al. (1999) Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk. EMBO J 18: 522-533.
46. Amuthan G, Biswas G, Ananadatheerthavarada HK, Vijayasarathy C, Shephard HM, et al. (2002) Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 21: 7839-49.
47. Jopling C, Sleep E, Raya M, Marti M, Raya A, et al. (2010) Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464: 606-609.
48. Kieken F, Mutsaers N, Dolmatova E, Virgil K, Wit AL, et al. (2009) Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction. Circ Res 104: 1103-1112.