Hyperin extracted from manchurian rhododendron leaf induces apoptosis in human endometrial cancer cells through a mitochondrial pathway

Asian Pacific Journal of Cancer Prevention

Volumn 13, Issue 8, 2012, Pages 3653-3656

  Li, Fu Rong ^a   Yu, Feng Xiu ^a   Yao, Shu Tong ^a   Si, Yan Hong ^a   Zhang, Wei ^a   Gao, Lin Lin ^a  

^a TAISHAN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Endometrial cancer cells; Hyperin

Indexed keywords

EID: 84873902253     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.8.3653     Document Type: Article

References (23)

1. Bustamante J, Caldas Lopes E, Garcia M, et al. (2004). Disruption of mitochondrial membrane potential during apoptosis induced by PSC 833 and CsA in multidrugresistant lymphoid leukemia. Toxicol Appl Pharmacol, 199, 44-51.
2. Choi DW (1995). Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci, 18, 58-60.
3. Desagher S, Martinou JC (2000). Mitochondria as the central control point of apoptosis. Trends Cell Biol, 10, 369-77.
4. El-Refael MF, Sarkar NH (2009). Snake venom inhibits the growth of mouse mammary tumor cells in vitro and in vivo. Toxicon, 54, 33-41.
5. Gao LL, Feng L, Yao Shu T, et al. (2011). Molecular mechanisms of celery seed extract induced apoptosis via s phase cell cycle arrest in the BGC-823 human stomach cancer cell line. Asian Pac J Cancer Prev, 12, 2601-6.
6. Han J, Goldstein LA, Gastman BR, et al.(2006).Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis. J Biol Chem, 281, 10153-63.
7. 2+ and voltage during anoxia/reoxygenation. Am J Physiol Cell Physiol, 280, 517-26.
8. Kruman I, Guo Q, Mattson MP (1998).Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells. J Neurosci Res, 51, 293-308.
9. Kaufmann SH (2001). Hengartner, Programmed cell death: alive and well in the new millennium. Trends Cell Biol, 11, 526-34.
10. Martikainen P, Kyprianou N, Tucker RW, et al. (1991). Programmed death of nonproliferating androgen-independent prostatic cancer cells. Cancer Res, 51, 4693-700.
11. Middleton EJ, Kandaswami C, Theoharides TC (2000). The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev, 52, 673-751.
12. Narendra H, Ray S, Rao L, et al. (2010). Malignant extrarenal rhabdoid tumor of the vulva in an adult. J Cancer Res Ther, 6, 82-5.
13. Nicholson, DW, Thornberry, NA (1997). Caspases: killer proteases. Trends Bio Chem Sci, 22, 299-306.
14. Nijveldt RJ, van Nood E, van Hoorn DE, et al. (2001). Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr, 74, 418-25.
15. Park, HJ, Kim, MJ, Ha E, et al. (2008). Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells, SNU-C4. Phytomedicine, 15, 147-51.
16. Rasmussen HE, Blobaum KR, Park YK, et al. (2008). Lipid extract of Nostoc commune var. sphaeroides Kutzing, a bluegreen alga, inhibits the activation of sterol regulatory element binding proteins in HepG2 cells. J Nutr, 138, 476-81.
17. Salvesen GS, Dixit VM (1997). Caspases: intracellular signaling by proteolysis. Cell, 91, 443-6.
18. Sara Leo, Katiuscia Bianchi, Marisa Brini et al. (2005). Mitochondrial calcium signalling in cell death. FEBS J, 272, 4013-22.
19. 2+]i in individual cells undergoing apoptosis. Cell Calcium, 25, 19-28.
20. Wang IK, Lin-Shiau SY, Lin JK, et al. (1999). Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. European Journal of Cancer, 35, 1517-25.
21. Yang J, Liu X, Bhalla K, et al. (1997). Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science, 275, 1129-32.
22. 2+]i in avian cochlear nucleus neurons: roles of protein kinases A and C and relation to cell death. J Neurophysiol, 79, 2288-302.
23. Zu Y, Liu X, Fu Y, et al. (2009). Cytotoxic activity of isoliquiritigenin towards CCRF-CEM leukemia cells and its effect on DNA damage. Planta Med, 75, 1134-40.