Multistage histopathological image segmentation of Iba1-stained murine microglias in a focal ischemia model: Methodological workflow and expert validation

Journal of Neuroscience Methods

Volumn 213, Issue 2, 2013, Pages 250-262

  Valous, Nektarios A ^a   Lahrmann, Bernd ^a   Zhou, Wei ^b   Veltkamp, Roland ^b   Grabe, Niels ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Brightfield microscopy; Cerebral ischemia; Digital neuropathology; Image segmentation; Microglia

Indexed keywords

ADAPTOR PROTEIN; IBA1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN ISCHEMIA; BRAIN TISSUE; CELL ACTIVATION; CELL COUNT; CONTROLLED STUDY; FILTRATION; HISTOGRAM; HISTOPATHOLOGY; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; METHODOLOGY; MICROGLIA; MOUSE; NONHUMAN; PATHOLOGIST; PRIORITY JOURNAL; VALIDATION STUDY; WORKFLOW;

ANIMALS; BRAIN ISCHEMIA; CELL COUNT; DISEASE MODELS, ANIMAL; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICROGLIA; STAINING AND LABELING; WORKFLOW;

EID: 84873865004     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2012.12.017     Document Type: Article

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