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Volumn 8, Issue 1, 2013, Pages

IGFBP-3 Inhibits Cytokine-Induced Insulin Resistance and Early Manifestations of Atherosclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; C REACTIVE PROTEIN; CYTOKINE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84873857197     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055084     Document Type: Article
Times cited : (49)

References (52)
  • 1
    • 74549159752 scopus 로고    scopus 로고
    • Prevalence of high body mass index in US children and adolescents, 2007-2008
    • Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM, (2010) Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA 303: 242-249.
    • (2010) JAMA , vol.303 , pp. 242-249
    • Ogden, C.L.1    Carroll, M.D.2    Curtin, L.R.3    Lamb, M.M.4    Flegal, K.M.5
  • 2
    • 0017042247 scopus 로고
    • The development of obesity, hyperinsulinemia, and hyperglycemia in ob/ob mice
    • Dubuc PU, (1976) The development of obesity, hyperinsulinemia, and hyperglycemia in ob/ob mice. Metabolism 25: 1567-1574.
    • (1976) Metabolism , vol.25 , pp. 1567-1574
    • Dubuc, P.U.1
  • 3
    • 0037432152 scopus 로고    scopus 로고
    • Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue
    • Ouchi N, Kihara S, Funahashi T, Nakamura T, Nishida M, et al. (2003) Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 107: 671-674.
    • (2003) Circulation , vol.107 , pp. 671-674
    • Ouchi, N.1    Kihara, S.2    Funahashi, T.3    Nakamura, T.4    Nishida, M.5
  • 4
    • 31044447347 scopus 로고    scopus 로고
    • Inflamed fat: what starts the fire
    • Neels JG, Olefsky JM, (2006) Inflamed fat: what starts the fire? J Clin Invest 116: 33-35.
    • (2006) J Clin Invest , vol.116 , pp. 33-35
    • Neels, J.G.1    Olefsky, J.M.2
  • 5
    • 0033304507 scopus 로고    scopus 로고
    • The insulin-like growth factor-binding protein (IGFBP) superfamily
    • Hwa V, Oh Y, Rosenfeld RG, (1999) The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev 20: 761-787.
    • (1999) Endocr Rev , vol.20 , pp. 761-787
    • Hwa, V.1    Oh, Y.2    Rosenfeld, R.G.3
  • 6
    • 34147183436 scopus 로고    scopus 로고
    • Association of total insulin-like growth factor-I, insulin-like growth factor binding protein-1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke
    • Kaplan RC, McGinn AP, Pollak MN, Kuller LH, Strickler HD, et al. (2007) Association of total insulin-like growth factor-I, insulin-like growth factor binding protein-1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke. J Clin Endocrinol Metab 92: 1319-1325.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1319-1325
    • Kaplan, R.C.1    McGinn, A.P.2    Pollak, M.N.3    Kuller, L.H.4    Strickler, H.D.5
  • 7
    • 79958799370 scopus 로고    scopus 로고
    • Serum Insulin-like Growth Factor-I and its Binding Protein 3 in their Relation to Intima Media Thickness: Results of the Study of Health in Pomerania (SHIP)
    • Spilcke-Liss E, Friedrich N, Dorr M, Schminke U, Volzke H, et al. (2011) Serum Insulin-like Growth Factor-I and its Binding Protein 3 in their Relation to Intima Media Thickness: Results of the Study of Health in Pomerania (SHIP). Clin Endocrinol (Oxf).
    • (2011) Clin Endocrinol (Oxf)
    • Spilcke-Liss, E.1    Friedrich, N.2    Dorr, M.3    Schminke, U.4    Volzke, H.5
  • 8
    • 12144287840 scopus 로고    scopus 로고
    • The IGF-I system component concentrations that decrease with ageing are lower in obesity in relationship to body mass index and body fat
    • Gomez JM, Maravall FJ, Gomez N, Navarro MA, Casamitjana R, et al. (2004) The IGF-I system component concentrations that decrease with ageing are lower in obesity in relationship to body mass index and body fat. Growth Horm IGF Res 14: 91-96.
    • (2004) Growth Horm IGF Res , vol.14 , pp. 91-96
    • Gomez, J.M.1    Maravall, F.J.2    Gomez, N.3    Navarro, M.A.4    Casamitjana, R.5
  • 9
    • 79953672049 scopus 로고    scopus 로고
    • Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury
    • Kielczewski JL, Hu P, Shaw LC, Li Calzi S, Mames RN, et al. (2011) Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury. Am J Pathol 178: 1517-1528.
    • (2011) Am J Pathol , vol.178 , pp. 1517-1528
    • Kielczewski, J.L.1    Hu, P.2    Shaw, L.C.3    Li Calzi, S.4    Mames, R.N.5
  • 10
    • 0027199617 scopus 로고
    • Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition
    • Oh Y, Muller HL, Lamson G, Rosenfeld RG, (1993) Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition. J Biol Chem 268: 14964-14971.
    • (1993) J Biol Chem , vol.268 , pp. 14964-14971
    • Oh, Y.1    Muller, H.L.2    Lamson, G.3    Rosenfeld, R.G.4
  • 11
    • 79957653825 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-3 suppresses tumor growth via activation of caspase-dependent apoptosis and cross-talk with NF-kappaB signaling
    • Han J, Jogie-Brahim S, Harada A, Oh Y, (2011) Insulin-like growth factor-binding protein-3 suppresses tumor growth via activation of caspase-dependent apoptosis and cross-talk with NF-kappaB signaling. Cancer Lett 307: 200-210.
    • (2011) Cancer Lett , vol.307 , pp. 200-210
    • Han, J.1    Jogie-Brahim, S.2    Harada, A.3    Oh, Y.4
  • 12
    • 79955959814 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-3 (IGFBP-3) blocks the effects of asthma by negatively regulating NF-kappaB signaling through IGFBP-3R-mediated activation of caspases
    • Lee YC, Jogie-Brahim S, Lee DY, Han J, Harada A, et al. (2011) Insulin-like growth factor-binding protein-3 (IGFBP-3) blocks the effects of asthma by negatively regulating NF-kappaB signaling through IGFBP-3R-mediated activation of caspases. J Biol Chem 286: 17898-17909.
    • (2011) J Biol Chem , vol.286 , pp. 17898-17909
    • Lee, Y.C.1    Jogie-Brahim, S.2    Lee, D.Y.3    Han, J.4    Harada, A.5
  • 13
    • 77956939368 scopus 로고    scopus 로고
    • Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer
    • Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, et al. (2010) Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer. J Biol Chem 285: 30233-30246.
    • (2010) J Biol Chem , vol.285 , pp. 30233-30246
    • Ingermann, A.R.1    Yang, Y.F.2    Han, J.3    Mikami, A.4    Garza, A.E.5
  • 14
    • 0025074841 scopus 로고
    • Evidence of enzymatic degradation of insulin-like growth factor-binding proteins in the 150K complex during pregnancy
    • Hossenlopp P, Segovia B, Lassarre C, Roghani M, Bredon M, et al. (1990) Evidence of enzymatic degradation of insulin-like growth factor-binding proteins in the 150K complex during pregnancy. J Clin Endocrinol Metab 71: 797-805.
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 797-805
    • Hossenlopp, P.1    Segovia, B.2    Lassarre, C.3    Roghani, M.4    Bredon, M.5
  • 15
    • 35349013381 scopus 로고    scopus 로고
    • Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells
    • AM HZ
    • AM HZ, Collard TJ, Malik K, Hicks DJ, Paraskeva C, et al. (2006) Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells. Int J Oncol 29: 1279-1286.
    • (2006) Int J Oncol , vol.29 , pp. 1279-1286
    • Collard, T.J.1    Malik, K.2    Hicks, D.J.3    Paraskeva, C.4
  • 16
    • 68549126809 scopus 로고    scopus 로고
    • Unraveling insulin-like growth factor binding protein-3 actions in human disease
    • Jogie-Brahim S, Feldman D, Oh Y, (2009) Unraveling insulin-like growth factor binding protein-3 actions in human disease. Endocr Rev 30: 417-437.
    • (2009) Endocr Rev , vol.30 , pp. 417-437
    • Jogie-Brahim, S.1    Feldman, D.2    Oh, Y.3
  • 17
    • 0028211161 scopus 로고
    • Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- to 150-kDa ternary complex
    • Bang P, Brismar K, Rosenfeld RG, (1994) Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- to 150-kDa ternary complex. J Clin Endocrinol Metab 78: 1119-1127.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1119-1127
    • Bang, P.1    Brismar, K.2    Rosenfeld, R.G.3
  • 18
    • 65249085713 scopus 로고    scopus 로고
    • In vitro hyperresponsiveness to tumor necrosis factor-alpha contributes to adipokine dysregulation in omental adipocytes of obese subjects
    • Maury E, Noel L, Detry R, Brichard SM, (2009) In vitro hyperresponsiveness to tumor necrosis factor-alpha contributes to adipokine dysregulation in omental adipocytes of obese subjects. J Clin Endocrinol Metab 94: 1393-1400.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1393-1400
    • Maury, E.1    Noel, L.2    Detry, R.3    Brichard, S.M.4
  • 19
    • 0030206997 scopus 로고    scopus 로고
    • Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus
    • Skolnik EY, Marcusohn J, (1996) Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus. Cytokine Growth Factor Rev 7: 161-173.
    • (1996) Cytokine Growth Factor Rev , vol.7 , pp. 161-173
    • Skolnik, E.Y.1    Marcusohn, J.2
  • 20
    • 0029849743 scopus 로고    scopus 로고
    • Structure, function, and regulation of the mammalian facilitative glucose transporter gene family
    • Olson AL, Pessin JE, (1996) Structure, function, and regulation of the mammalian facilitative glucose transporter gene family. Annu Rev Nutr 16: 235-256.
    • (1996) Annu Rev Nutr , vol.16 , pp. 235-256
    • Olson, A.L.1    Pessin, J.E.2
  • 21
    • 77953508725 scopus 로고    scopus 로고
    • Adiponectin: a key player in obesity related disorders
    • Matsuzawa Y, (2010) Adiponectin: a key player in obesity related disorders. Curr Pharm Des 16: 1896-1901.
    • (2010) Curr Pharm Des , vol.16 , pp. 1896-1901
    • Matsuzawa, Y.1
  • 22
    • 0034748889 scopus 로고    scopus 로고
    • Mutation of three critical amino acids of the N-terminal domain of IGF-binding protein-3 essential for high affinity IGF binding
    • Buckway CK, Wilson EM, Ahlsen M, Bang P, Oh Y, et al. (2001) Mutation of three critical amino acids of the N-terminal domain of IGF-binding protein-3 essential for high affinity IGF binding. J Clin Endocrinol Metab 86: 4943-4950.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4943-4950
    • Buckway, C.K.1    Wilson, E.M.2    Ahlsen, M.3    Bang, P.4    Oh, Y.5
  • 23
    • 78149358733 scopus 로고    scopus 로고
    • The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease
    • Ouwens DM, Sell H, Greulich S, Eckel J, (2010) The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease. J Cell Mol Med 14: 2223-2234.
    • (2010) J Cell Mol Med , vol.14 , pp. 2223-2234
    • Ouwens, D.M.1    Sell, H.2    Greulich, S.3    Eckel, J.4
  • 24
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, et al. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112: 1796-1808.
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3    Rosenbaum, M.4    Leibel, R.L.5
  • 25
    • 79751496064 scopus 로고    scopus 로고
    • Alternative macrophage activation and metabolism
    • Odegaard JI, Chawla A, (2011) Alternative macrophage activation and metabolism. Annu Rev Pathol 6: 275-297.
    • (2011) Annu Rev Pathol , vol.6 , pp. 275-297
    • Odegaard, J.I.1    Chawla, A.2
  • 26
    • 79959783758 scopus 로고    scopus 로고
    • Defining macrophage phenotype and function in adipose tissue
    • Dalmas E, Clement K, Guerre-Millo M, (2011) Defining macrophage phenotype and function in adipose tissue. Trends Immunol 32: 307-314.
    • (2011) Trends Immunol , vol.32 , pp. 307-314
    • Dalmas, E.1    Clement, K.2    Guerre-Millo, M.3
  • 27
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A, (2006) Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 177: 7303-7311.
    • (2006) J Immunol , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 29
    • 0025185678 scopus 로고
    • Close correlation of intra-abdominal fat accumulation to hypertension in obese women
    • Kanai H, Matsuzawa Y, Kotani K, Keno Y, Kobatake T, et al. (1990) Close correlation of intra-abdominal fat accumulation to hypertension in obese women. Hypertension 16: 484-490.
    • (1990) Hypertension , vol.16 , pp. 484-490
    • Kanai, H.1    Matsuzawa, Y.2    Kotani, K.3    Keno, Y.4    Kobatake, T.5
  • 30
    • 0028363169 scopus 로고
    • Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men
    • Nakamura T, Tokunaga K, Shimomura I, Nishida M, Yoshida S, et al. (1994) Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men. Atherosclerosis 107: 239-246.
    • (1994) Atherosclerosis , vol.107 , pp. 239-246
    • Nakamura, T.1    Tokunaga, K.2    Shimomura, I.3    Nishida, M.4    Yoshida, S.5
  • 31
    • 33846263404 scopus 로고    scopus 로고
    • Adipocytokines - novel link between inflammation and vascular function
    • Guzik TJ, Mangalat D, Korbut R, (2006) Adipocytokines- novel link between inflammation and vascular function? J Physiol Pharmacol 57: 505-528.
    • (2006) J Physiol Pharmacol , vol.57 , pp. 505-528
    • Guzik, T.J.1    Mangalat, D.2    Korbut, R.3
  • 32
    • 33846436784 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo
    • Kim HS, Ali O, Shim M, Lee KW, Vuguin P, et al. (2007) Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo. Pediatr Res 61: 159-164.
    • (2007) Pediatr Res , vol.61 , pp. 159-164
    • Kim, H.S.1    Ali, O.2    Shim, M.3    Lee, K.W.4    Vuguin, P.5
  • 33
    • 33845488341 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB
    • AM HZ
    • Williams AC, Smartt H, AM HZ, Macfarlane M, Paraskeva C, et al. (2007) Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB. Cell Death Differ 14: 137-145.
    • (2007) Cell Death Differ , vol.14 , pp. 137-145
    • Williams, A.C.1    Smartt, H.2    Macfarlane, M.3    Paraskeva, C.4
  • 34
    • 0036838455 scopus 로고    scopus 로고
    • Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice
    • Silha JV, Gui Y, Murphy LJ, (2002) Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice. Am J Physiol Endocrinol Metab 283: E937-945.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Silha, J.V.1    Gui, Y.2    Murphy, L.J.3
  • 35
    • 0030032795 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes
    • Moses AC, Young SC, Morrow LA, O'Brien M, Clemmons DR, (1996) Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes 45: 91-100.
    • (1996) Diabetes , vol.45 , pp. 91-100
    • Moses, A.C.1    Young, S.C.2    Morrow, L.A.3    O'Brien, M.4    Clemmons, D.R.5
  • 36
    • 84455191521 scopus 로고    scopus 로고
    • Role of IGFBP-3 in the regulation of beta-cell mass during obesity: adipose tissue/beta-cell cross talk
    • Palau N, Rebuffat SA, Altirriba J, Piquer S, Hanzu FA, et al. (2012) Role of IGFBP-3 in the regulation of beta-cell mass during obesity: adipose tissue/beta-cell cross talk. Endocrinology 153: 177-187.
    • (2012) Endocrinology , vol.153 , pp. 177-187
    • Palau, N.1    Rebuffat, S.A.2    Altirriba, J.3    Piquer, S.4    Hanzu, F.A.5
  • 37
    • 78249289434 scopus 로고    scopus 로고
    • The role of IGF-1 resistance in obesity and type 2 diabetes-mellitus-related insulin resistance and vascular disease
    • Gatenby VK, Kearney MT, (2010) The role of IGF-1 resistance in obesity and type 2 diabetes-mellitus-related insulin resistance and vascular disease. Expert Opin Ther Targets 14: 1333-1342.
    • (2010) Expert Opin Ther Targets , vol.14 , pp. 1333-1342
    • Gatenby, V.K.1    Kearney, M.T.2
  • 38
    • 0242495440 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-3 is associated with the presence and extent of coronary arteriosclerosis
    • Schuler-Luttmann S, Monnig G, Enbergs A, Schulte H, Breithardt G, et al. (2000) Insulin-like growth factor-binding protein-3 is associated with the presence and extent of coronary arteriosclerosis. Arterioscler Thromb Vasc Biol 20: E10-15.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20
    • Schuler-Luttmann, S.1    Monnig, G.2    Enbergs, A.3    Schulte, H.4    Breithardt, G.5
  • 39
    • 0033136406 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein (IGFBP) proteolysis: occurrence, identification, role and regulation
    • Maile LA, Holly JM, (1999) Insulin-like growth factor binding protein (IGFBP) proteolysis: occurrence, identification, role and regulation. Growth Horm IGF Res 9: 85-95.
    • (1999) Growth Horm IGF Res , vol.9 , pp. 85-95
    • Maile, L.A.1    Holly, J.M.2
  • 40
    • 0038070060 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein proteolysis
    • Bunn RC, Fowlkes JL, (2003) Insulin-like growth factor binding protein proteolysis. Trends Endocrinol Metab 14: 176-181.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 176-181
    • Bunn, R.C.1    Fowlkes, J.L.2
  • 41
    • 0030755476 scopus 로고    scopus 로고
    • Human pregnancy serum contains at least two distinct proteolytic activities with the ability to degrade insulin-like growth factor binding protein-3
    • Bang P, Fielder PJ, (1997) Human pregnancy serum contains at least two distinct proteolytic activities with the ability to degrade insulin-like growth factor binding protein-3. Endocrinology 138: 3912-3917.
    • (1997) Endocrinology , vol.138 , pp. 3912-3917
    • Bang, P.1    Fielder, P.J.2
  • 42
    • 0029433606 scopus 로고
    • The role of glycosylation in the action of IGFBP-3
    • Firth SM, Baxter RC, (1995) The role of glycosylation in the action of IGFBP-3. Prog Growth Factor Res 6: 223-229.
    • (1995) Prog Growth Factor Res , vol.6 , pp. 223-229
    • Firth, S.M.1    Baxter, R.C.2
  • 43
    • 3142690729 scopus 로고    scopus 로고
    • Differential impact of simple childhood obesity on the components of the growth hormone-insulin-like growth factor (IGF)-IGF binding proteins axis
    • Ballerini MG, Ropelato MG, Domene HM, Pennisi P, Heinrich JJ, et al. (2004) Differential impact of simple childhood obesity on the components of the growth hormone-insulin-like growth factor (IGF)-IGF binding proteins axis. J Pediatr Endocrinol Metab 17: 749-757.
    • (2004) J Pediatr Endocrinol Metab , vol.17 , pp. 749-757
    • Ballerini, M.G.1    Ropelato, M.G.2    Domene, H.M.3    Pennisi, P.4    Heinrich, J.J.5
  • 44
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5
  • 45
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR, (2007) Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes 56: 16-23.
    • (2007) Diabetes , vol.56 , pp. 16-23
    • Lumeng, C.N.1    Deyoung, S.M.2    Bodzin, J.L.3    Saltiel, A.R.4
  • 46
    • 44349161098 scopus 로고    scopus 로고
    • Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance
    • Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, et al. (2008) Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab 7: 496-507.
    • (2008) Cell Metab , vol.7 , pp. 496-507
    • Odegaard, J.I.1    Ricardo-Gonzalez, R.R.2    Red Eagle, A.3    Vats, D.4    Morel, C.R.5
  • 47
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
    • Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, et al. (2008) Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab 7: 485-495.
    • (2008) Cell Metab , vol.7 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3    Gangl, M.R.4    Fitzgerald, K.5
  • 48
    • 13344261982 scopus 로고    scopus 로고
    • Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion
    • Brand K, Page S, Rogler G, Bartsch A, Brandl R, et al. (1996) Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest 97: 1715-1722.
    • (1996) J Clin Invest , vol.97 , pp. 1715-1722
    • Brand, K.1    Page, S.2    Rogler, G.3    Bartsch, A.4    Brandl, R.5
  • 49
    • 0033991177 scopus 로고    scopus 로고
    • Activated nuclear factor-kappaB is present in the coronary vasculature in experimental hypercholesterolemia
    • Wilson SH, Caplice NM, Simari RD, Holmes DR Jr, Carlson PJ, et al. (2000) Activated nuclear factor-kappaB is present in the coronary vasculature in experimental hypercholesterolemia. Atherosclerosis 148: 23-30.
    • (2000) Atherosclerosis , vol.148 , pp. 23-30
    • Wilson, S.H.1    Caplice, N.M.2    Simari, R.D.3    Holmes Jr., D.R.4    Carlson, P.J.5
  • 51
    • 45449114246 scopus 로고    scopus 로고
    • Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules
    • Tikellis C, Jandeleit-Dahm KA, Sheehy K, Murphy A, Chin-Dusting J, et al. (2008) Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules. Atherosclerosis 199: 55-64.
    • (2008) Atherosclerosis , vol.199 , pp. 55-64
    • Tikellis, C.1    Jandeleit-Dahm, K.A.2    Sheehy, K.3    Murphy, A.4    Chin-Dusting, J.5
  • 52
    • 0035757218 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis: the value of the high-sensitivity C-reactive protein assay as a risk marker
    • Jialal I, Devaraj S, (2001) Inflammation and atherosclerosis: the value of the high-sensitivity C-reactive protein assay as a risk marker. Am J Clin Pathol 116 (Suppl):: S108-115.
    • (2001) Am J Clin Pathol , vol.116 , Issue.SUPPL.
    • Jialal, I.1    Devaraj, S.2


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