Carbon tetrachloride-induced hepatic injury through formation of oxidized diacylglycerol and activation of the PKC/NF-κB pathway

Laboratory Investigation

Volumn 93, Issue 2, 2013, Pages 218-229

  Toriumi, Kentaro ^a   Horikoshi, Yosuke ^a   Yoshiyuki Osamura, R ^a   Yamamoto, Yorihiro ^b   Nakamura, Naoya ^a   Takekoshi, Susumu ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

hepatic injury; oxidative stress; oxidized diacylglycerol; protein kinase C

Indexed keywords

ALPHA TOCOPHEROL; CARBON TETRACHLORIDE; DIACYLGLYCEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETAI; PROTEIN KINASE C BETAII; PROTEIN KINASE C DELTA; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIPID PEROXIDATION; LIVER INJURY; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT;

ACUTE LUNG INJURY; ANIMALS; CARBON TETRACHLORIDE; CELL FRACTIONATION; DIGLYCERIDES; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NF-KAPPA B; PEROXIDES; PROTEIN ISOFORMS; PROTEIN KINASE C; RATS; SIGNAL TRANSDUCTION;

EID: 84873836056     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2012.145     Document Type: Article

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