P-Rex1 Cooperates with PDGFRβ to Drive Cellular Migration in 3D Microenvironments

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Campbell, Andrew D ^a   Lawn, Samuel ^a,c   McGarry, Lynn C ^a   Welch, Heidi C ^b   Ozanne, Bradford W ^a   Norman, Jim C ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE DEPENDENT RAC EXCHANGER 1; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN TIAM1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER INVASION; CELL IMMORTALIZATION; CELL INVASION; CELL MIGRATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FETUS; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MELANOMA CELL; MICROENVIRONMENT; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; THREE DIMENSIONAL MICROENVIRONMENT;

CELL LINE, TUMOR; CELL MOVEMENT; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MACROMOLECULAR SUBSTANCES; MELANOMA; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, SMALL INTERFERING; TUMOR MICROENVIRONMENT;

EID: 84873835397     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053982     Document Type: Article

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