Toll-like receptor agonists and febrile range hyperthermia synergize to induce heat shock protein 70 expression and extracellular release

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2756-2766

  Gupta, Aditi ^a   Cooper, Zachary A ^a   Tulapurkar, Mohan E ^a   Potla, Ratnakar ^a   Maity, Tapan ^a   Hasday, Jeffrey D ^a,b   Singh, Ishwar S ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL-FREE; CORE TEMPERATURE; EXTRACELLULAR; GENE MODIFICATION; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HISTONE H3; HSP70 EXPRESSION; INTRATRACHEAL; LUNG TISSUE; MAP KINASE; P38 MAPK; PATHWAY INHIBITORS; PRE-TREATMENT; RAW CELLS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

BIOLOGICAL ORGANS; GENETIC ENGINEERING; MAMMALS; PHOSPHORYLATION; TISSUE;

PROTEINS;

HEAT SHOCK PROTEIN 70; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; CORE TEMPERATURE; DISEASE SEVERITY; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FEBRILE RANGE HYPERTHERMIA; HUMAN; HUMAN CELL; HYPERTHERMIA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SEPSIS; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; FEVER; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; RNA, SMALL INTERFERING; SEPSIS; SHOCK; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 84873834308     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.427336     Document Type: Article

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