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Volumn 8, Issue 1, 2013, Pages

Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin

Author keywords

[No Author keywords available]

Indexed keywords

DELTA LACTOFERRIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR; IRON BINDING PROTEIN; ISOPROTEIN; LACTOFERRIN; MITOGEN ACTIVATED PROTEIN KINASE P38; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 84873807144     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055338     Document Type: Article
Times cited : (11)

References (44)
  • 1
    • 28444462150 scopus 로고    scopus 로고
    • Lactoferrin: a modulator of immune and inflammatory responses
    • Legrand D, Elass E, Carpentier M, Mazurier J, (2005) Lactoferrin: a modulator of immune and inflammatory responses. Cell Mol Life Sci 62: 2549-2559.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2549-2559
    • Legrand, D.1    Elass, E.2    Carpentier, M.3    Mazurier, J.4
  • 4
    • 33748416650 scopus 로고    scopus 로고
    • Interactions of lactoferrin with cells involved in immune function
    • Legrand D, Elass E, Carpentier M, Mazurier J, (2006) Interactions of lactoferrin with cells involved in immune function. Biochem Cell Biol 84: 282-290.
    • (2006) Biochem Cell Biol , vol.84 , pp. 282-290
    • Legrand, D.1    Elass, E.2    Carpentier, M.3    Mazurier, J.4
  • 5
    • 0030946524 scopus 로고    scopus 로고
    • Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines
    • Siebert PD, Huang BC, (1997) Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines. Proc Natl Acad Sci U S A 94: 2198-2203.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2198-2203
    • Siebert, P.D.1    Huang, B.C.2
  • 6
    • 13244259275 scopus 로고    scopus 로고
    • Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer
    • Benaïssa M, Peyrat JP, Hornez L, Mariller C, Mazurier J, et al. (2005) Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer. Int J Cancer 114: 299-306.
    • (2005) Int J Cancer , vol.114 , pp. 299-306
    • Benaïssa, M.1    Peyrat, J.P.2    Hornez, L.3    Mariller, C.4    Mazurier, J.5
  • 7
    • 58149115086 scopus 로고    scopus 로고
    • Proteomic approach to the identification of novel delta-lactoferrin target genes: Characterization of DcpS, an mRNA scavenger decapping enzyme
    • Mariller C, Hardivillé S, Hoedt E, Benaïssa M, Mazurier J, et al. (2009) Proteomic approach to the identification of novel delta-lactoferrin target genes: Characterization of DcpS, an mRNA scavenger decapping enzyme. Biochimie 91: 109-122.
    • (2009) Biochimie , vol.91 , pp. 109-122
    • Mariller, C.1    Hardivillé, S.2    Hoedt, E.3    Benaïssa, M.4    Mazurier, J.5
  • 8
    • 9144245356 scopus 로고    scopus 로고
    • Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells
    • Legrand D, Vigie K, Said EA, Elass E, Masson M, et al. (2004) Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells. Eur J Biochem 271: 303-317.
    • (2004) Eur J Biochem , vol.271 , pp. 303-317
    • Legrand, D.1    Vigie, K.2    Said, E.A.3    Elass, E.4    Masson, M.5
  • 9
    • 34247116048 scopus 로고    scopus 로고
    • Human delta-lactoferrin is a transcription factor that enhances Skp1 (S-phase kinase-associated protein) gene expression
    • Mariller C, Benaïssa M, Hardivillé S, Breton M, Pradelle G, et al. (2007) Human delta-lactoferrin is a transcription factor that enhances Skp1 (S-phase kinase-associated protein) gene expression. FEBS J 274: 2038-2053.
    • (2007) FEBS J , vol.274 , pp. 2038-2053
    • Mariller, C.1    Benaïssa, M.2    Hardivillé, S.3    Breton, M.4    Pradelle, G.5
  • 10
    • 3342888949 scopus 로고    scopus 로고
    • Lactoferrin and host defence: an overview of its immuno-modulating and anti-inflammatory properties
    • Legrand D, Elass E, Pierce A, Mazurier J, (2004) Lactoferrin and host defence: an overview of its immuno-modulating and anti-inflammatory properties. Biometals 17: 225-229.
    • (2004) Biometals , vol.17 , pp. 225-229
    • Legrand, D.1    Elass, E.2    Pierce, A.3    Mazurier, J.4
  • 11
    • 33749266896 scopus 로고    scopus 로고
    • Breast cancer markers
    • Giancotti V, (2006) Breast cancer markers. Cancer Lett 243: 145-159.
    • (2006) Cancer Lett , vol.243 , pp. 145-159
    • Giancotti, V.1
  • 12
    • 0026716209 scopus 로고
    • Regulation of cytokine release from mononuclear cells by the iron-binding protein lactoferrin
    • Crouch SP, Slater KJ, Fletcher J, (1992) Regulation of cytokine release from mononuclear cells by the iron-binding protein lactoferrin. Blood 80: 235-240.
    • (1992) Blood , vol.80 , pp. 235-240
    • Crouch, S.P.1    Slater, K.J.2    Fletcher, J.3
  • 13
    • 77951225235 scopus 로고    scopus 로고
    • Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling
    • Ando K, Hasegawa K, Shindo K, Furusawa T, Fujino T, et al. (2010) Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling. FEBS J 277: 2051-2066.
    • (2010) FEBS J , vol.277 , pp. 2051-2066
    • Ando, K.1    Hasegawa, K.2    Shindo, K.3    Furusawa, T.4    Fujino, T.5
  • 14
    • 69849092519 scopus 로고    scopus 로고
    • Iron-saturated lactoferrin stimulates cell cycle progression through PI3K/Akt pathway
    • Lee SH, Pyo CW, Hahm DH, Kim J, Choi SY, (2009) Iron-saturated lactoferrin stimulates cell cycle progression through PI3K/Akt pathway. Mol Cells 28: 37-42.
    • (2009) Mol Cells , vol.28 , pp. 37-42
    • Lee, S.H.1    Pyo, C.W.2    Hahm, D.H.3    Kim, J.4    Choi, S.Y.5
  • 16
    • 58149134848 scopus 로고    scopus 로고
    • Requirement of the JNK-associated Bcl-2 pathway for human lactoferrin-induced apoptosis in the Jurkat leukemia T cell line
    • Lee SH, Park SW, Pyo CW, Yoo NK, Kim J, et al. (2009) Requirement of the JNK-associated Bcl-2 pathway for human lactoferrin-induced apoptosis in the Jurkat leukemia T cell line. Biochimie 91: 102-108.
    • (2009) Biochimie , vol.91 , pp. 102-108
    • Lee, S.H.1    Park, S.W.2    Pyo, C.W.3    Yoo, N.K.4    Kim, J.5
  • 17
    • 25844474349 scopus 로고    scopus 로고
    • Human lactoferrin exerts bi-directional actions on PC12 cell survival via ERK1/2 pathway
    • Lin TY, Chiou SH, Chen M, Kuo CD, (2005) Human lactoferrin exerts bi-directional actions on PC12 cell survival via ERK1/2 pathway. Biochem Biophys Res Commun 337: 330-336.
    • (2005) Biochem Biophys Res Commun , vol.337 , pp. 330-336
    • Lin, T.Y.1    Chiou, S.H.2    Chen, M.3    Kuo, C.D.4
  • 18
    • 0032585082 scopus 로고    scopus 로고
    • Matrix attachment region sequences enhanced the expression frequency of a whey acidic protein/human lactoferrin fusion gene in the mammary gland of transgenic mice
    • Lee TH, Kim SJ, Han YM, Yu DY, Lee CS, et al. (1998) Matrix attachment region sequences enhanced the expression frequency of a whey acidic protein/human lactoferrin fusion gene in the mammary gland of transgenic mice. Mol Cells 8: 530-536.
    • (1998) Mol Cells , vol.8 , pp. 530-536
    • Lee, T.H.1    Kim, S.J.2    Han, Y.M.3    Yu, D.Y.4    Lee, C.S.5
  • 19
  • 21
    • 0031394781 scopus 로고    scopus 로고
    • Activation of macrophages by lactoferrin: secretion of TNF-alpha, IL-8 and NO
    • Sorimachi K, Akimoto K, Hattori Y, Ieiri T, Niwa A, (1997) Activation of macrophages by lactoferrin: secretion of TNF-alpha, IL-8 and NO. Biochem Mol Biol Int. 43: 79-87.
    • (1997) Biochem Mol Biol Int , vol.43 , pp. 79-87
    • Sorimachi, K.1    Akimoto, K.2    Hattori, Y.3    Ieiri, T.4    Niwa, A.5
  • 22
    • 77649271930 scopus 로고    scopus 로고
    • miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
    • Chiyomaru T, Enokida H, Tatarano S, Kawahara K, Uchida Y, et al. (2010) miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer 102: 883-891.
    • (2010) Br J Cancer , vol.102 , pp. 883-891
    • Chiyomaru, T.1    Enokida, H.2    Tatarano, S.3    Kawahara, K.4    Uchida, Y.5
  • 23
    • 35649018633 scopus 로고    scopus 로고
    • EWI-2/CD316 is an inducible receptor of HSPA8 on human dendritic cells
    • Kettner S, Kalthoff F, Graf P, Priller E, Kricek F, et al. (2007) EWI-2/CD316 is an inducible receptor of HSPA8 on human dendritic cells. Mol Cell Biol 27: 7718-7726.
    • (2007) Mol Cell Biol , vol.27 , pp. 7718-7726
    • Kettner, S.1    Kalthoff, F.2    Graf, P.3    Priller, E.4    Kricek, F.5
  • 24
    • 34047169674 scopus 로고    scopus 로고
    • Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future
    • de Jong J, Looijenga LH, (2006) Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future. Crit Rev Oncog 12: 171-203.
    • (2006) Crit Rev Oncog , vol.12 , pp. 171-203
    • de Jong, J.1    Looijenga, L.H.2
  • 25
    • 79960268598 scopus 로고    scopus 로고
    • Dissecting the role of SALL4, a newly identified stem cell factor, in chronic myelogenous leukemia
    • Lu J, Ma Y, Kong N, Alipio Z, Gao C, et al. (2011) Dissecting the role of SALL4, a newly identified stem cell factor, in chronic myelogenous leukemia. Leukemia 25: 1211-1213.
    • (2011) Leukemia , vol.25 , pp. 1211-1213
    • Lu, J.1    Ma, Y.2    Kong, N.3    Alipio, Z.4    Gao, C.5
  • 26
    • 29644443953 scopus 로고    scopus 로고
    • Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation
    • Jung CG, Kim HJ, Kawaguchi M, Khanna KK, Hida H, et al. (2005) Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development 132: 5137-5145.
    • (2005) Development , vol.132 , pp. 5137-5145
    • Jung, C.G.1    Kim, H.J.2    Kawaguchi, M.3    Khanna, K.K.4    Hida, H.5
  • 27
    • 77953021835 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 and MK2, MK3 and MK5: ménage à trois or ménage à quatre
    • Shiryaev A, Moens U, (2010) Mitogen-activated protein kinase p38 and MK2, MK3 and MK5: ménage à trois or ménage à quatre? Cell Signal 22: 1185-1192.
    • (2010) Cell Signal , vol.22 , pp. 1185-1192
    • Shiryaev, A.1    Moens, U.2
  • 28
    • 0035834720 scopus 로고    scopus 로고
    • Human neutrophil lactoferrin trans-activates the matrix metalloproteinase 1 gene through stress-activated MAPK signaling modules
    • Oh SM, Hahm DH, Kim IH, Choi SY, (2001) Human neutrophil lactoferrin trans-activates the matrix metalloproteinase 1 gene through stress-activated MAPK signaling modules. J Biol Chem 276: 42575-42579.
    • (2001) J Biol Chem , vol.276 , pp. 42575-42579
    • Oh, S.M.1    Hahm, D.H.2    Kim, I.H.3    Choi, S.Y.4
  • 29
    • 75549090255 scopus 로고    scopus 로고
    • Mammalian Rif1 contributes to replication stress survival and homology-directed repair
    • Buonomo SB, Wu Y, Ferguson D, de Lange T, (2009) Mammalian Rif1 contributes to replication stress survival and homology-directed repair. J Cell Biol 187: 385-398.
    • (2009) J Cell Biol , vol.187 , pp. 385-398
    • Buonomo, S.B.1    Wu, Y.2    Ferguson, D.3    de Lange, T.4
  • 30
    • 7744231642 scopus 로고    scopus 로고
    • Suppressive effects of milk-derived lactoferrin on psychological stress in adult rats
    • Kamemori N, Takeuchi T, Hayashida K, Harada E, (2004) Suppressive effects of milk-derived lactoferrin on psychological stress in adult rats. Brain Res 1029: 34-40.
    • (2004) Brain Res , vol.1029 , pp. 34-40
    • Kamemori, N.1    Takeuchi, T.2    Hayashida, K.3    Harada, E.4
  • 31
    • 0033575702 scopus 로고    scopus 로고
    • Purification and characterization of human RNPS1: a general activator of pre-mRNA splicing
    • Mayeda A, Badolato J, Kobayashi R, Zhang MQ, Gardiner EM, et al. (1999) Purification and characterization of human RNPS1: a general activator of pre-mRNA splicing. EMBO J 18: 4560-4570.
    • (1999) EMBO J , vol.18 , pp. 4560-4570
    • Mayeda, A.1    Badolato, J.2    Kobayashi, R.3    Zhang, M.Q.4    Gardiner, E.M.5
  • 32
    • 1642540255 scopus 로고    scopus 로고
    • Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo
    • Sakashita E, Tatsumi S, Werner D, Endo H, Mayeda A, (2004) Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo. Mol Cell Biol 24: 1174-1187.
    • (2004) Mol Cell Biol , vol.24 , pp. 1174-1187
    • Sakashita, E.1    Tatsumi, S.2    Werner, D.3    Endo, H.4    Mayeda, A.5
  • 33
    • 0036154096 scopus 로고    scopus 로고
    • Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons
    • Rossoll W, Kroning AK, Ohndorf UM, Steegborn C, Jablonka S, et al. (2002) Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Hum Mol Genet 11: 93-105.
    • (2002) Hum Mol Genet , vol.11 , pp. 93-105
    • Rossoll, W.1    Kroning, A.K.2    Ohndorf, U.M.3    Steegborn, C.4    Jablonka, S.5
  • 34
    • 78650446117 scopus 로고    scopus 로고
    • DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps
    • Tseng CK, Liu HL, Cheng SC, (2011) DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps. RNA 17: 145-154.
    • (2011) RNA , vol.17 , pp. 145-154
    • Tseng, C.K.1    Liu, H.L.2    Cheng, S.C.3
  • 35
    • 70349558633 scopus 로고    scopus 로고
    • Lactoferrin modulation of BCG-infected dendritic cell functions
    • Hwang SA, Actor JK, (2009) Lactoferrin modulation of BCG-infected dendritic cell functions. Int Immunol 21: 1185-1197.
    • (2009) Int Immunol , vol.21 , pp. 1185-1197
    • Hwang, S.A.1    Actor, J.K.2
  • 36
    • 28344453346 scopus 로고    scopus 로고
    • Mammalian lactoferrin receptors: structure and function
    • Suzuki YA, Lopez V, Lönnerdal B, (2005) Mammalian lactoferrin receptors: structure and function. Cell Mol Life Sci 62: 2560-2575.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2560-2575
    • Suzuki, Y.A.1    Lopez, V.2    Lönnerdal, B.3
  • 37
    • 78651434044 scopus 로고    scopus 로고
    • Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: the constitutively active orphan GPCR GPR18 as novel drug target
    • Qin Y, Verdegaal EM, Siderius M, Bebelman JP, Smit MJ, et al. (2011) Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: the constitutively active orphan GPCR GPR18 as novel drug target. Pigment Cell Melanoma Res 24: 207-218.
    • (2011) Pigment Cell Melanoma Res , vol.24 , pp. 207-218
    • Qin, Y.1    Verdegaal, E.M.2    Siderius, M.3    Bebelman, J.P.4    Smit, M.J.5
  • 38
    • 79955761342 scopus 로고    scopus 로고
    • GPR54 is a target for suppression of metastasis in endometrial cancer
    • Kang HS, Baba T, Mandai M, Matsumura N, Hamanishi J, et al. (2011) GPR54 is a target for suppression of metastasis in endometrial cancer. Mol Cancer Ther 10: 580-590.
    • (2011) Mol Cancer Ther , vol.10 , pp. 580-590
    • Kang, H.S.1    Baba, T.2    Mandai, M.3    Matsumura, N.4    Hamanishi, J.5
  • 39
    • 79959610178 scopus 로고    scopus 로고
    • GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness
    • Zajac M, Law J, Cvetkovic DD, Pampillo M, McColl L, et al. (2011) GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness. PLoS One 6: e21599.
    • (2011) PLoS One , vol.6
    • Zajac, M.1    Law, J.2    Cvetkovic, D.D.3    Pampillo, M.4    McColl, L.5
  • 40
    • 69449100367 scopus 로고    scopus 로고
    • Human RIF1 encodes an anti-apoptotic factor required for DNA repair
    • Wang H, Zhao A, Chen L, Zhong X, Liao J, et al. (2009) Human RIF1 encodes an anti-apoptotic factor required for DNA repair. Carcinogenesis 30: 1314-1319.
    • (2009) Carcinogenesis , vol.30 , pp. 1314-1319
    • Wang, H.1    Zhao, A.2    Chen, L.3    Zhong, X.4    Liao, J.5
  • 41
    • 34547838641 scopus 로고    scopus 로고
    • The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway
    • Viegas MH, Gehring NH, Breit S, Hentze MW, Kulozik AE, (2007) The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway. Nucleic Acids Res 35: 4542-4551.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4542-4551
    • Viegas, M.H.1    Gehring, N.H.2    Breit, S.3    Hentze, M.W.4    Kulozik, A.E.5
  • 42
    • 84861363011 scopus 로고    scopus 로고
    • Delta-lactoferrin, an intracellular lactoferrin isoform that acts as a transcription factor
    • Mariller C, Hardiville S, Hoedt E, Huvent I, Pina-Canseco S, et al. (2012) Delta-lactoferrin, an intracellular lactoferrin isoform that acts as a transcription factor. Biochem Cell Biol 90: 307-319.
    • (2012) Biochem Cell Biol , vol.90 , pp. 307-319
    • Mariller, C.1    Hardiville, S.2    Hoedt, E.3    Huvent, I.4    Pina-Canseco, S.5
  • 43
    • 79952338489 scopus 로고    scopus 로고
    • SALL4 is essential for cancer cell proliferation and is overexpressed at early clinical stages in breast cancer
    • Kobayashi D, Kuribayshi K, Tanaka M, Watanabe N, (2011) SALL4 is essential for cancer cell proliferation and is overexpressed at early clinical stages in breast cancer. Int J Oncol 38: 933-939.
    • (2011) Int J Oncol , vol.38 , pp. 933-939
    • Kobayashi, D.1    Kuribayshi, K.2    Tanaka, M.3    Watanabe, N.4
  • 44
    • 79960831107 scopus 로고    scopus 로고
    • Overexpression of SALL4 in lung cancer and its importance in cell proliferation
    • Kobayashi D, Kuribayashi K, Tanaka M, Watanabe N, (2011) Overexpression of SALL4 in lung cancer and its importance in cell proliferation. Oncol Rep 26: 965-970.
    • (2011) Oncol Rep , vol.26 , pp. 965-970
    • Kobayashi, D.1    Kuribayashi, K.2    Tanaka, M.3    Watanabe, N.4


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