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Volumn 109, Issue SUPPL. 2, 2013, Pages

Gut immune system and oral tolerance

Author keywords

Mucosa associated lymphoid tissue; Mucosal immunity; Oral immunisation; Regulatory T cells

Indexed keywords

AUTOANTIGEN; LATENCY ASSOCIATED PEPTIDE; MONOCLONAL ANTIBODY CD3; TRANSFORMING GROWTH FACTOR BETA;

EID: 84873800448     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512005223     Document Type: Article
Times cited : (49)

References (53)
  • 1
    • 0026579998 scopus 로고
    • The mucosal immune system: From fundamental concepts to vaccine development
    • McGhee JR, Mestecky J, Dertzbaugh MT, et al. (1992) The mucosal immune system: from fundamental concepts to vaccine development. Vaccine 10, 75-88.
    • (1992) Vaccine , vol.10 , pp. 75-88
    • McGhee, J.R.1    Mestecky, J.2    Dertzbaugh, M.T.3
  • 2
    • 24144450331 scopus 로고    scopus 로고
    • Mucosal epithelium in health and disease
    • Ponda PP & Mayer L (2005) Mucosal epithelium in health and disease. Curr Mol Med 5, 549-556.
    • (2005) Curr Mol Med , vol.5 , pp. 549-556
    • Ponda, P.P.1    Mayer, L.2
  • 4
    • 83055184684 scopus 로고    scopus 로고
    • Epithelial barrier biology: Good fences make good neighbours
    • Moens E & Veldhoen M (2012) Epithelial barrier biology: good fences make good neighbours. Immunology 135, 1-8.
    • (2012) Immunology , vol.135 , pp. 1-8
    • Moens, E.1    Veldhoen, M.2
  • 5
    • 4043088519 scopus 로고    scopus 로고
    • Anatomical and cellular basis of immunity and tolerance in the intestine
    • Mowat AM, Millington OR & Chirdo FG (2004) Anatomical and cellular basis of immunity and tolerance in the intestine. J Pediatr Gastroenterol Nutr 39, Suppl. 3, S723-S724.
    • (2004) J Pediatr Gastroenterol Nutr , vol.39 , Issue.SUPPL. 3
    • Mowat, A.M.1    Millington, O.R.2    Chirdo, F.G.3
  • 6
    • 77958505148 scopus 로고    scopus 로고
    • GALT: Organization and dynamics leading to IgA synthesis
    • Suzuki K, Kawamoto S, Maruya M, et al. (2010) GALT: organization and dynamics leading to IgA synthesis. Adv Immunol 107, 153-185.
    • (2010) Adv Immunol , vol.107 , pp. 153-185
    • Suzuki, K.1    Kawamoto, S.2    Maruya, M.3
  • 7
    • 0038316325 scopus 로고    scopus 로고
    • Anatomical basis of tolerance and immunity to intestinal antigens
    • Mowat AM (2003) Anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol 3, 331-341.
    • (2003) Nat Rev Immunol , vol.3 , pp. 331-341
    • Mowat, A.M.1
  • 8
    • 80054963764 scopus 로고    scopus 로고
    • Regulation of the polymeric immunoglobulin receptor and IgA transport: New advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity
    • Johansen FE & Kaetzel CS (2011) Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity. Mucosal Immunol 4, 598-602.
    • (2011) Mucosal Immunol , vol.4 , pp. 598-602
    • Johansen, F.E.1    Kaetzel, C.S.2
  • 9
    • 80054882496 scopus 로고    scopus 로고
    • Mucosal macrophages in intestinal homeostasis and inflammation
    • Mowat AM & Bain CC (2011) Mucosal macrophages in intestinal homeostasis and inflammation. J Innate Immun 3, 550-564.
    • (2011) J Innate Immun , vol.3 , pp. 550-564
    • Mowat, A.M.1    Bain, C.C.2
  • 10
    • 79959664629 scopus 로고    scopus 로고
    • The light and dark sides of intestinal intraepithelial lymphocytes
    • Cheroutre H, Lambolez F & Mucida D (2011) The light and dark sides of intestinal intraepithelial lymphocytes. Nat Rev Immunol 11, 445-456.
    • (2011) Nat Rev Immunol , vol.11 , pp. 445-456
    • Cheroutre, H.1    Lambolez, F.2    Mucida, D.3
  • 11
    • 78650060920 scopus 로고    scopus 로고
    • Flow cytometry of intestinal intraepithelial lymphocytes in celiac disease
    • Leon F (2011) Flow cytometry of intestinal intraepithelial lymphocytes in celiac disease. J Immunol Methods 363, 177-186.
    • (2011) J Immunol Methods , vol.363 , pp. 177-186
    • Leon, F.1
  • 12
    • 70450064812 scopus 로고    scopus 로고
    • Mucosal immunity: Induction, dissemination, and effector functions
    • Brandtzaeg P (2009) Mucosal immunity: induction, dissemination, and effector functions. Scand J Immunol 70, 505-515.
    • (2009) Scand J Immunol , vol.70 , pp. 505-515
    • Brandtzaeg, P.1
  • 13
    • 33846781580 scopus 로고    scopus 로고
    • The extrathymic T-cell differentiation in the murine gut
    • Rocha B (2007) The extrathymic T-cell differentiation in the murine gut. Immunol Rev 215, 166-177.
    • (2007) Immunol Rev , vol.215 , pp. 166-177
    • Rocha, B.1
  • 15
    • 0032403527 scopus 로고    scopus 로고
    • Extrathymic T cell differentiation in the human intestine early in life
    • Howie D, Spencer J, DeLord D, et al. (1998) Extrathymic T cell differentiation in the human intestine early in life. J Immunol 161, 5862-5872.
    • (1998) J Immunol , vol.161 , pp. 5862-5872
    • Howie, D.1    Spencer, J.2    Delord, D.3
  • 16
    • 77958157901 scopus 로고    scopus 로고
    • Sampling of the intestinal microbiota by epithelial M cells
    • Pickard JM & Chervonsky AV (2010) Sampling of the intestinal microbiota by epithelial M cells. Curr Gastroenterol Rep 12, 331-339.
    • (2010) Curr Gastroenterol Rep , vol.12 , pp. 331-339
    • Pickard, J.M.1    Chervonsky, A.V.2
  • 18
    • 0033564584 scopus 로고    scopus 로고
    • Antigen presentation by intestinal epithelial cells
    • Blumberg RS, Lencer WI, Zhu X, et al. (1999) Antigen presentation by intestinal epithelial cells. Immunol Lett 69, 7-11.
    • (1999) Immunol Lett , vol.69 , pp. 7-11
    • Blumberg, R.S.1    Lencer, W.I.2    Zhu, X.3
  • 19
    • 77958475318 scopus 로고    scopus 로고
    • Intestinal dendritic cells
    • Rescigno M (2010) Intestinal dendritic cells. Adv Immunol 107, 109-138.
    • (2010) Adv Immunol , vol.107 , pp. 109-138
    • Rescigno, M.1
  • 20
    • 0035321325 scopus 로고    scopus 로고
    • Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
    • Rescigno M, Urbano M, Valzasina B, et al. (2001) Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat Immunol 2, 361-367.
    • (2001) Nat Immunol , vol.2 , pp. 361-367
    • Rescigno, M.1    Urbano, M.2    Valzasina, B.3
  • 21
    • 0035316302 scopus 로고    scopus 로고
    • Periscope, up! Monitoring microbes in the intestine
    • Gewirtz AT & Madara JL (2001) Periscope, up! Monitoring microbes in the intestine. Nat Immunol 2, 288-290.
    • (2001) Nat Immunol , vol.2 , pp. 288-290
    • Gewirtz, A.T.1    Madara, J.L.2
  • 22
    • 58449109276 scopus 로고    scopus 로고
    • Structure and function of the gut mucosal immune system
    • Pabst R & Rothkotter HJ (2006) Structure and function of the gut mucosal immune system. Adv Exp Med Biol 579, 1-14.
    • (2006) Adv Exp Med Biol , vol.579 , pp. 1-14
    • Pabst, R.1    Rothkotter, H.J.2
  • 23
    • 71449090908 scopus 로고    scopus 로고
    • Gut microbiota and probiotics in modulation of epithelium and gut-associated lymphoid tissue function
    • Sanz Y & De Palma G (2009) Gut microbiota and probiotics in modulation of epithelium and gut-associated lymphoid tissue function. Int Rev Immunol 28, 397-413.
    • (2009) Int Rev Immunol , vol.28 , pp. 397-413
    • Sanz, Y.1    De Palma, G.2
  • 24
    • 17444448063 scopus 로고    scopus 로고
    • Lens culinaris, Phaseolus vulgaris and vicia faba lectins specifically trigger IL-8 production by the human colon carcinoma cell line CACO-2
    • Rodriguez-Juan C, Perez-Blas M, Suarez-Garcia E, et al. (2000) Lens culinaris, Phaseolus vulgaris and vicia faba lectins specifically trigger IL-8 production by the human colon carcinoma cell line CACO-2. Cytokine 12, 1284-1287.
    • (2000) Cytokine , vol.12 , pp. 1284-1287
    • Rodriguez-Juan, C.1    Perez-Blas, M.2    Suarez-Garcia, E.3
  • 25
    • 0035673410 scopus 로고    scopus 로고
    • Cell surface phenotype and cytokine secretion in Caco-2 cell cultures: Increased RANTES production and IL-2 transcription upon stimulation with IL-1beta
    • Rodriguez-Juan C, Perez-Blas M, Valeri AP, et al. (2001) Cell surface phenotype and cytokine secretion in Caco-2 cell cultures: increased RANTES production and IL-2 transcription upon stimulation with IL-1beta. Tissue Cell 33, 570-579.
    • (2001) Tissue Cell , vol.33 , pp. 570-579
    • Rodriguez-Juan, C.1    Perez-Blas, M.2    Valeri, A.P.3
  • 26
    • 0031467722 scopus 로고    scopus 로고
    • Cell surface phenotype and ultramicroscopic analysis of purified human enterocytes: A possible antigen-presenting cell in the intestine
    • Martin-Villa JM, Ferre-Lopez S, Lopez-Suarez JC, et al. (1997) Cell surface phenotype and ultramicroscopic analysis of purified human enterocytes: a possible antigen-presenting cell in the intestine. Tissue Antigens 50, 586-592.
    • (1997) Tissue Antigens , vol.50 , pp. 586-592
    • Martin-Villa, J.M.1    Ferre-Lopez, S.2    Lopez-Suarez, J.C.3
  • 27
    • 79953057255 scopus 로고    scopus 로고
    • Integration of genetic and immunological insights into a model of celiac disease pathogenesis
    • Abadie V, Sollid LM, Barreiro LB, et al. (2011) Integration of genetic and immunological insights into a model of celiac disease pathogenesis. Annu Rev Immunol 29, 493-525.
    • (2011) Annu Rev Immunol , vol.29 , pp. 493-525
    • Abadie, V.1    Sollid, L.M.2    Barreiro, L.B.3
  • 28
    • 0037782141 scopus 로고    scopus 로고
    • Immunobiology of epithelial chemokines in the intestinal mucosa
    • Dwinell MB, Johanesen PA & Smith JM (2003) Immunobiology of epithelial chemokines in the intestinal mucosa. Surgery 133, 601-607.
    • (2003) Surgery , vol.133 , pp. 601-607
    • Dwinell, M.B.1    Johanesen, P.A.2    Smith, J.M.3
  • 29
    • 84856368530 scopus 로고    scopus 로고
    • Enterocytes: Active cells in tolerance to food and microbial antigens in the gut
    • Miron N & Cristea V (2012) Enterocytes: active cells in tolerance to food and microbial antigens in the gut. Clin Exp Immunol 167, 405-412.
    • (2012) Clin Exp Immunol , vol.167 , pp. 405-412
    • Miron, N.1    Cristea, V.2
  • 31
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4\+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S (2004) Naturally arising CD4\+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22, 531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 32
    • 33845662118 scopus 로고    scopus 로고
    • Oral tolerance: Therapeutic implications for autoimmune diseases
    • Faria AM & Weiner HL (2006) Oral tolerance: therapeutic implications for autoimmune diseases. Clin Dev Immunol 13, 143-157.
    • (2006) Clin Dev Immunol , vol.13 , pp. 143-157
    • Faria, A.M.1    Weiner, H.L.2
  • 33
    • 84856759921 scopus 로고    scopus 로고
    • Disarming suppressor cells to improve immunotherapy
    • Whiteside TL (2012) Disarming suppressor cells to improve immunotherapy. Cancer Immunol Immunother 61, 283-288.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 283-288
    • Whiteside, T.L.1
  • 34
    • 76349096767 scopus 로고    scopus 로고
    • Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8\+ Treg cells are associated with immunological remission of lupus
    • Zhang L, Bertucci AM, Ramsey-Goldman R, et al. (2009) Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8\+ Treg cells are associated with immunological remission of lupus. J Immunol 183, 6346-6358.
    • (2009) J Immunol , vol.183 , pp. 6346-6358
    • Zhang, L.1    Bertucci, A.M.2    Ramsey-Goldman, R.3
  • 35
    • 73249148836 scopus 로고    scopus 로고
    • Novel CD8\+ Treg suppress EAE by TGF-beta-and IFN-gamma-dependent mechanisms
    • Chen ML, Yan BS, Kozoriz D, et al. (2009) Novel CD8\+ Treg suppress EAE by TGF-beta-and IFN-gamma-dependent mechanisms. Eur J Immunol 39, 3423-3435.
    • (2009) Eur J Immunol , vol.39 , pp. 3423-3435
    • Chen, M.L.1    Yan, B.S.2    Kozoriz, D.3
  • 37
    • 3042838388 scopus 로고    scopus 로고
    • Latent TGF-beta binding proteins: Extracellular matrix association and roles in TGF-beta activation
    • Hyytiainen M, Penttinen C & Keski-Oja J (2004) Latent TGF-beta binding proteins: extracellular matrix association and roles in TGF-beta activation. Crit Rev Clin Lab Sci 41, 233-264.
    • (2004) Crit Rev Clin Lab Sci , vol.41 , pp. 233-264
    • Hyytiainen, M.1    Penttinen, C.2    Keski-Oja, J.3
  • 38
    • 34249678653 scopus 로고    scopus 로고
    • TGFbeta signalling in control of T-cell-mediated self-reactivity
    • Rubtsov YP & Rudensky AY (2007) TGFbeta signalling in control of T-cell-mediated self-reactivity. Nat Rev Immunol 7, 443-453.
    • (2007) Nat Rev Immunol , vol.7 , pp. 443-453
    • Rubtsov, Y.P.1    Rudensky, A.Y.2
  • 39
    • 17044425656 scopus 로고    scopus 로고
    • Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4\+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis
    • Kohm AP, Williams JS, Bickford AL, et al. (2005) Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4\+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis. J Immunol 174, 4525-4534.
    • (2005) J Immunol , vol.174 , pp. 4525-4534
    • Kohm, A.P.1    Williams, J.S.2    Bickford, A.L.3
  • 40
    • 79954459142 scopus 로고    scopus 로고
    • Murine CD4 T cells produce a new form of TGF-beta as measured by a newly developed TGF-beta bioassay
    • Oida T & Weiner HL (2011) Murine CD4 T cells produce a new form of TGF-beta as measured by a newly developed TGF-beta bioassay. PLoS One 6, e18365.
    • (2011) PLoS One , vol.6
    • Oida, T.1    Weiner, H.L.2
  • 41
    • 34248592104 scopus 로고    scopus 로고
    • T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1-and Th17-cell differentiation
    • Li MO, Wan YY & Flavell RA (2007) T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1-and Th17-cell differentiation. Immunity 26, 579-591.
    • (2007) Immunity , vol.26 , pp. 579-591
    • Li, M.O.1    Wan, Y.Y.2    Flavell, R.A.3
  • 42
    • 0035801335 scopus 로고    scopus 로고
    • Cell contactdependent immunosuppression by CD4(\+)CD25(\+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K, Kitani A & Strober W (2001) Cell contactdependent immunosuppression by CD4(\+)CD25(\+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 194, 629-644.
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 43
    • 78649650472 scopus 로고    scopus 로고
    • TGF-beta induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction
    • Oida T & Weiner HL (2010) TGF-beta induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction. PLoS One 5, e15523.
    • (2010) PLoS One , vol.5
    • Oida, T.1    Weiner, H.L.2
  • 44
    • 0026046280 scopus 로고
    • Antigen-driven bystander suppression after oral administration of antigens
    • Miller A, Lider O & Weiner HL (1991) Antigen-driven bystander suppression after oral administration of antigens. J Exp Med 174, 791-798.
    • (1991) J Exp Med , vol.174 , pp. 791-798
    • Miller, A.1    Lider, O.2    Weiner, H.L.3
  • 45
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang J, Markovic-Plese S, Lacet B, et al. (1994) Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J Exp Med 179, 973-984.
    • (1994) J Exp Med , vol.179 , pp. 973-984
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3
  • 46
    • 72349096793 scopus 로고    scopus 로고
    • Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit
    • Sun JB, Czerkinsky C & Holmgren J (2010) Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit. Scand J Immunol 71, 1-11.
    • (2010) Scand J Immunol , vol.71 , pp. 1-11
    • Sun, J.B.1    Czerkinsky, C.2    Holmgren, J.3
  • 47
    • 84863174201 scopus 로고    scopus 로고
    • B lymphocytes treated in vitro with antigen coupled to cholera toxin B subunit induce antigen-specific Foxp3(\+) regulatory T cells and protect against experimental autoimmune encephalomyelitis
    • Sun JB, Czerkinsky C & Holmgren J (2012) B lymphocytes treated in vitro with antigen coupled to cholera toxin B subunit induce antigen-specific Foxp3(\+) regulatory T cells and protect against experimental autoimmune encephalomyelitis. J Immunol 188, 1686-1697.
    • (2012) J Immunol , vol.188 , pp. 1686-1697
    • Sun, J.B.1    Czerkinsky, C.2    Holmgren, J.3
  • 48
    • 0034873558 scopus 로고    scopus 로고
    • Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells
    • George-Chandy A, Eriksson K, Lebens M, et al. (2001) Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells. Infect Immun 69, 5716-5725.
    • (2001) Infect Immun , vol.69 , pp. 5716-5725
    • George-Chandy, A.1    Eriksson, K.2    Lebens, M.3
  • 49
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin e expression in the brain
    • Khoury SJ, Hancock WW & Weiner HL (1992) Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain. J Exp Med 176, 1355-1364.
    • (1992) J Exp Med , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 50
    • 0034991196 scopus 로고    scopus 로고
    • Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes
    • Slavin AJ, Maron R & Weiner HL (2001) Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes. Int Immunol 13, 825-833.
    • (2001) Int Immunol , vol.13 , pp. 825-833
    • Slavin, A.J.1    Maron, R.2    Weiner, H.L.3
  • 51
    • 0141796312 scopus 로고    scopus 로고
    • TGF-betadependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • Belghith M, Bluestone JA, Barriot S, et al. (2003) TGF-betadependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9, 1202-1208.
    • (2003) Nat Med , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3
  • 52
    • 53049110126 scopus 로고    scopus 로고
    • New immunosuppressive approaches: Oral administration of CD3-specific antibody to treat autoimmunity
    • Ochi H, Abraham M, Ishikawa H, et al. (2008) New immunosuppressive approaches: oral administration of CD3-specific antibody to treat autoimmunity. J Neurol Sci 274, 9-12.
    • (2008) J Neurol Sci , vol.274 , pp. 9-12
    • Ochi, H.1    Abraham, M.2    Ishikawa, H.3
  • 53
    • 20444371569 scopus 로고    scopus 로고
    • Neuroprotection by IL-10-producing MOG CD4\+ T cells following ischemic stroke
    • Frenkel D, Huang Z, Maron R, et al. (2005) Neuroprotection by IL-10-producing MOG CD4\+ T cells following ischemic stroke. J Neurol Sci 233, 125-132.
    • (2005) J Neurol Sci , vol.233 , pp. 125-132
    • Frenkel, D.1    Huang, Z.2    Maron, R.3


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