Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase

Phytomedicine

Volumn 20, Issue 3-4, 2013, Pages 270-274

  Bero, J ^a   Beaufay, C ^a   Hannaert, V ^a   Herent M F ^a   Michels, P A ^a   Quetin Leclercq, J ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Essential oil; Glyceraldehyde 3 phosphate dehydrogenase; Keetia leucantha; Trypanosoma brucei

Indexed keywords

ALPHA IONONE; ANTITRYPANOSOMAL AGENT; BETA IONONE; BETULIC ACID; CARYOPHYLLENE; DICHLOROMETHANE; ESSENTIAL OIL; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; ISOPHYTOL; KEETIA LEUCANTHA PLANT EXTRACT; MYRISTIC ACID; OLEANOLIC ACID; OLEIC ACID; PALMITIC ACID; PLANT EXTRACT; SURAMIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; KEETIA LEUCANTHA; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI;

GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; OILS, VOLATILE; PARASITIC SENSITIVITY TESTS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; RUBIACEAE; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

KEETIA; LEISHMANIA MEXICANA MEXICANA; PLASMODIUM FALCIPARUM; TRYPANOSOMA BRUCEI; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84873744991     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.10.010     Document Type: Article

References (29)

1. F. Abe, T. Yamauchi, T. Nagao, J. Kinjo, H. Okabe, H. Higo, and H. Akahane Ursolic acid as a trypanocidal constituent in rosemary Biological and Pharmaceutical Bulletin 25 2002 1485 1487
2. A.M. Aronov, S. Suresh, F.S. Buckner, W.C. Van Voorhis, C.L. Verlinde, F.R. Opperdoes, W.G. Hol, and M.H. Gelb Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase Proceedings of the National Academic Science of the United States of America 96 1999 4273 4278
3. B.M. Bakker, P.A. Michels, F.R. Opperdoes, and H.V. Westerhoff What controls glycolysis in bloodstream form Trypanosoma brucei? Journal of Biological Chemistry 274 1999 14551 14559
4. J. Bero, H. Ganfon, M.C. Jonville, M. Frederich, F. Gbaguidi, P. Demol, M. Moudachirou, and J. Quetin-Leclercq In vitro antiplasmodial activity of plants used in Benin in traditional medicine to treat malaria Journal of Ethnopharmacology 122 2009 439 444
5. J. Bero, V. Hannaert, G. Chataigne, M.-F. Herent, and J. Quetin-Leclercq In vitro antitrypanosomal and antileishmanial activity of plants used in Benin in traditional medicine and bio-guided fractionation of the most active extract Journal of Ethnopharmacology 137 2011 998 1002
6. D.F. Bisaggio, L. Campanati, R.C. Pinto, and T. Souto-Padron Effect of suramin on trypomastigote forms of Trypanosoma cruzi: changes on cell motility and on the ultrastructure of the flagellum-cell body attachment region Acta Tropica 98 2006 162 175
7. R. Brun, and Z.R. Lun Drug-sensitivity of Chinese Trypanosoma-evansi and Trypanosoma-equiperdum isolates Veterinary Parasitology 52 1994 37 46
8. G.-Y. Chen, X.-X. Luo, C.-R. Han, Z.-L. Jiang, and Z.-R. Mo GC-MS analysis of essential oils from the leaves of Canthium horridum Hebei Daxue Xuebao, Ziran Kexueban 27 2007 486 488
9. S. Claustre, C. Denier, F. Lakhdar-Ghazal, A. Lougare, C. Lopez, N. Chevalier, P.A. Michels, J. Perie, and M. Willson Exploring the active site of Trypanosoma brucei phosphofructokinase by inhibition studies: specific irreversible inhibition Biochemistry 41 2002 10183 10193
10. R. Denayer, and B. Tilquin Détermination des indices de rétention de composants d'huiles essentielles Rivista Italiana Eppos 30 1994 7 12
11. Drugs for Neglected Diseases initiative, 2011. Human African Trypanosomiasis. http://www.dndi.org/diseases/hat.html.
12. A.H. Fairlamb, F.R. Opperdoes, and P. Borst New approach to screening drugs for activity against African trypanosomes Nature 265 1977 270 271
13. E.O. Fukushima, H. Seki, K. Ohyama, E. Ono, N. Umemoto, M. Mizutani, K. Saito, and T. Muranaka CYP716A Subfamily members are multifunctional oxidases in triterpenoid biosynthesis Plant and Cell Physiology 52 2011 2050 2061
14. J.L. Gelpi, J.J. Aviles, M. Busquets, S. Imperial, A. Mazo, A. Cortes, D.J. Halsall, and J.J. Holbrook A theoretical approach to the discrimination and characterization of the different classes of reversible inhibitors Journal of Chemical Education 70 1993 805
15. V. Hannaert, M. Callens, F.R. Opperdoes, and P.A. Michels Purification and characterization of the native and the recombinant Leishmania mexicana glycosomal glyceraldehyde-3-phosphate dehydrogenase European Journal of Biochemistry 225 1994 143 149
16. V. Hannaert, F.R. Opperdoes, and P.A. Michels Glycosomal glyceraldehyde-3-phosphate dehydrogenase of Trypanosoma brucei and Trypanosoma cruzi: expression in Escherichia coli, purification, and characterization of the enzymes Protein Expression and Purification 6 1995 244 250
17. M.-F. Herent, V. De Bie, and B. Tilquin Determination of new retention indices for quick identification of essential oils compounds Journal of Pharmaceutical and Biomedical Analysis 43 2007 886 892
18. S. Hoet, F. Opperdoes, R. Brun, V. Adjakidje, and J. Quetin-Leclercq In vitro antitrypanosomal activity of ethnopharmacologically selected Beninese plants Journal of Ethnopharmacology 91 2004 37 42
19. S. Hoet, L. Pieters, G.G. Muccioli, J.L. Habib-Jiwan, F.R. Opperdoes, and J. Quetin-Leclercq Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds Journal of Natural Products 70 2007 1360 1363
20. S. Hoet, C. Stevigny, S. Block, F. Opperdoes, P. Colson, B. Baldeyrou, A. Lansiaux, C. Bailly, and J. Quetin-Leclercq Alkaloids from Cassytha filiformis and related aporphines: Antitrypanosomal activity, cytotoxicity, and interaction with DNA and topoisomerases Planta Medica 70 2004 407 413
21. S. Hoet, C. Stevigny, M.-F. Herent, and J. Quetin-Leclercq Antitrypanosomal compounds from the leaf essential oil of Strychnos spinosa Planta Medica 72 2006 480 482
22. S. Jager, H. Trojan, T. Kopp, M.N. Laszczyk, and A. Scheffler Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts Molecules 14 2009 2016 2031
23. I. Kohler, K. Jenett-Siems, C. Kraft, K. Siems, D. Abbiw, U. Bienzle, and E. Eich Herbal remedies traditionally used against malaria in Ghana: bioassay-guided fractionation of Microglossa pyrifolia (Asteraceae) Zeitschrift fur Naturforschung C 57 2002 1022 1027
24. B. Nyasse, J.J. Nono, Y. Nganso, I. Ngantchou, and B. Schneider Uapaca genus (Euphorbiaceae), a good source of betulinic acid Fitoterapia 80 2009 32 34
25. A.T.C. Taketa, S.C.B. Gnoatto, G. Gosmann, V.S. Pires, E.P. Schenkel, and D. Guillaume Triterpenoids from Brazilian Ilex species and their in vitro antitrypanosomal activity Journal of Natural Products 67 2004 1697 1700
26. C.L. Verlinde, V. Hannaert, C. Blonski, M. Willson, J.J. Perie, L.A. Fothergill-Gilmore, F.R. Opperdoes, M.H. Gelb, W.G. Hol, and P.A. Michels Glycolysis as a target for the design of new anti-trypanosome drugs Drug Resistance Updates 4 2001 50 65
27. H. Wagner Synergy research: approaching a new generation of phytopharmaceuticals Fitoterapia 82 2011 34 37
28. M. Willson, N. Lauth, J. Perie, M. Callens, and F.R. Opperdoes Inhibition of glyceraldehyde-3-phosphate dehydrogenase by phosphorylated epoxides and alpha-enones Biochemistry 33 1994 214 220
29. World Health Organisation (WHO), 2012. African trypanosomiasis (sleeping sickness). http://www.who.int/mediacentre/factsheets/fs259/en/.