Therapeutic potential of B and T lymphocyte attenuator expressed on CD8+ T cells for contact hypersensitivity

Journal of Investigative Dermatology

Volumn 133, Issue 3, 2013, Pages 702-711

  Nakagomi, Daiki ^a   Suzuki, Kotaro ^a   Hosokawa, Junichi ^a   Kobayashi, Yoshihisa ^a   Suto, Akira ^a   Takatori, Hiroaki ^a   Watanabe, Norihiko ^a   Matsue, Hiroyuki ^a   Murphy, Theresa L ^b   Murphy, Kenneth M ^b   Shimada, Shinji ^c   Nakajima, Hiroshi ^a  

^a CHIBA UNIVERSITY   (Japan)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B AND T LYMPHOCYTE ATTENUATOR; CD28 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXOCYTOSIS; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SCID MOUSE; WILD TYPE;

EID: 84873743274     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.396     Document Type: Article

References (35)

1. Albring JC, Sandau MM, Rapaport AS et al. (2010) Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression. J Exp Med 207: 2551-9
2. Betts MR, Brenchley JM, Price DA et al. (2003) Sensitive and viable identification of antigen-specific CD8\+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 281: 65-78
3. Cai G, Freeman GJ (2009) The CD160, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation. Immunol Rev 229: 244-58
4. Cavani A (2008) T regulatory cells in contact hypersensitivity. Curr Opin Allergy Clin Immunol 8: 294-8
5. Chen L (2004) Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nat Rev Immunol 4: 336-47
6. Deppong C, Juehne TI, Hurchla M et al. (2006) B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation. J Immunol 176: 3909-13
7. Derré L, Rivals J-P, Jandus C et al. (2010) BTLA mediates inhibition of human tumor-specific CD8\+ T cells that can be partially reversed by vaccination. J Clin Invest 120: 157-67
8. Dubois B, Chapat L, Goubier A et al. (2003) Innate CD4\+ CD25\+ regulatory T cells are required for oral tolerance and inhibition of CD8\+ T cells mediating skin inflammation. Blood 102: 3295-301
9. Gomez de Agüero M, Vocanson M, Hacini-Rachinel F et al. (2012) Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(\+) T cells and activating Foxp3(\+) regulatory T cells. J Clin Invest 122: 1700-11
10. Greenwald RJ, Freeman GJ, Sharpe AH (2005) The B7 family revisited. Annu Rev Immunol 23: 515-48
11. Groom JR, Luster AD (2011) CXCR3 in T cell function. Exp Cell Res 317: 620-31
12. Kaplan DH, Igyarto BZ, Gaspari AA (2012) Early immune events in the induction of allergic contact dermatitis. Nat Rev Immunol 12: 114-24
13. Kaplan DH (2010) In vivo function of Langerhans cells and dermal dendritic cells. Trends Immunol 31: 446-51
14. Kehren J, Desvignes C, Krasteva M et al. (1999) Cytotoxicity is mandatory for CD8\+ T cell-mediated contact hypersensitivity. J Exp Med 189: 779-86
15. Kish DD, Li X, Fairchild RL (2009) CD8 T cells producing IL-17 and IFN-g initiate the innate immune response required for responses to antigen skin challenge. J Immunol 182: 5949-59
16. Krieg C, Boyman O, Fu YX et al. (2007) B and T lymphocyte attenuator regulates CD8\+ T cell-intrinsic homeostasis and memory cell generation. Nat Immunol 8: 162-71
17. Lepenies B, Pfeffer K, Hurchla MA et al. (2007) Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malaria. J Immunol 179: 4093-100
18. Liu X, Alexiou M, Martin-Orozco N et al. (2009) A critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction. J Immunol 182: 4516-20
19. Martin SF, Esser PR, Weber FC et al. (2011) Mechanisms of chemical-induced innate immunity in allergic contact dermatitis. Allergy 66: 1152-63
20. Martin SF (2004) T lymphocyte-mediated immune responses to chemical haptens and metal ions: implications for allergic and autoimmune disease. Int Arch Allergy Immunol 134: 186-98
21. Murphy KM, Nelson CA, Sedy JR (2006) Balancing co-stimulation and inhibition with BTLA and HVEM. Nat Rev Immunol 6: 671-81
22. Murphy TL, Murphy KM (2010) Slow down and survive: enigmatic immunoregulation by BTLA and HVEM. Annu Rev Immunol 28: 389-411
23. Nuriya S, Enomoto S, Azuma M (2001) The role of CTLA-4 in murine contact hypersensitivity. J Invest Dermatol 116: 764-8
24. Ring S, Schafer SC, Mahnke K et al. (2006) CD4\+ CD25\+ regulatory T cells suppress contact hypersensitivity reactions by blocking influx of effector T cells into inflamed tissue. Eur J Immunol 36: 2981-92
25. Serriari N-E, Gondois-Rey F, Guillaume Y et al. (2010) B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function. J Immunol 185: 3140-8
26. Suto A, Kashiwakuma D, Kagami S et al. (2008) Development and characterization of IL-21-producing CD4\+ T cells. J Exp Med 205: 1369-79
27. Tamachi T, Watanabe N, Oya Y et al. (2007) B and T lymphocyte attenuator inhibits antigen-induced eosinophil recruitment into the airways. Int Arch Allergy Immunol 143: s50-5
28. Tao R, Wang L, Han R et al. (2005) Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts. J Immunol 175: 5774-82
29. Tao R, Wang L, Murphy KM et al. (2008) Regulatory T cell expression of herpesvirus entry mediator suppresses the function of B and T lymphocyte attenuator-positive effector T cells. J Immunol 180: 6649-55
30. Tsushima F, Iwai H, Otsuki N et al. (2003) Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses. Eur J Immunol 33: 2773-82
31. Usatine RP, Riojas M (2010) Diagnosis and management of contact dermatitis. Am Fam Physician 82: 249-55
32. Vocanson M, Rozieres A, Hennino A et al. (2010) Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells. J Allergy Clin Immunol 126: 280-9
33. Vocanson M, Hennino A, Rozieres A et al. (2009) Effector and regulatory mechanisms in allergic contact dermatitis. Allergy 64: 1699-714
34. Watanabe N, Gavrieli M, Sedy JR et al. (2003) BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol 4: 670-9
35. Zhang N, Bevan MJ (2011) CD8\+ T cells: foot soldiers of immune system. Immunity 35: 161-8