Circulating sICAM-1 and sE-Selectin as biomarker of infection and prognosis in patients with systemic inflammatory response syndrome

European Journal of Internal Medicine

Volumn 24, Issue 2, 2013, Pages 132-138

  De Pablo, Raúl ^a,b   Monserrat, Jorge ^b   Reyes, Eduardo ^b   Díaz, David ^b   Rodríguez Zapata, Manuel ^b,c   De La Hera, Antonio ^b   Prieto, Alfredo ^b   Álvarez Mon, Melchor ^b,c  

^a HOSPITAL UNIVERSITARIO PRÍNCIPE DE ASTURIAS   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

^c HOSPITAL UNIVERSITARIO DE GUADALAJARA   (Spain)

Author keywords

Fatal outcome; Sepsis; Soluble adhesion molecules; Systemic inflammatory response syndrome (SIRS); Vascular endothelium

Indexed keywords

BIOLOGICAL MARKER; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 2; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROGNOSIS; PROSPECTIVE STUDY; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

BIOLOGICAL MARKERS; DIAGNOSIS, DIFFERENTIAL; E-SELECTIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INCIDENCE; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; ROC CURVE; SEVERITY OF ILLNESS INDEX; SPAIN; SURVIVAL RATE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84873734800     PISSN: 09536205     EISSN: 18790828     Source Type: Journal    
DOI: 10.1016/j.ejim.2012.10.009     Document Type: Article

References (50)

1. J.M. Harlan, and R.K. Winn Leukocyte-endothelial interactions: clinical trials of anti-adhesion therapy Crit Care Med 30 2002 S214 S219
2. W.A. Muller Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response Trends Immunol 24 2003 327 334
3. W.A. Muller Leukocyte-endothelial cell interactions in the inflammatory response Lab Invest 82 2002 521 533
4. R. Pigott, L.P. Dillon, I.H. Hemingway, and A.J. Gearing Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells Biochem Biophys Res Commun 187 1992 584 589
5. J.C. Giddings Soluble adhesion molecules in inflammatory and vascular diseases Biochem Soc Trans 33 2005 406 408
6. R.C. Bone, R.A. Balk, F.B. Cerra, R.P. Dellinger, A.M. Fein, and W.A. Knaus Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine Chest 101 1992 1644 1655
7. K. Peters, R.E. Unger, J. Brunner, and C.J. Kirkpatrick Molecular basis of endothelial dysfunction in sepsis Cardiovasc Res 60 2003 49 57
8. S. Gando, T. Kameue, N. Matsuda, M. Hayakawa, T. Ishitani, and Y. Morimoto Combined activation of coagulation and inflammation has an important role in multiple organ dysfunction and poor outcome after severe trauma Thromb Haemost 88 2002 943 949
9. A. Geppert, G. Zorn, G.D. Karth, M. Haumer, M. Gwechenberger, and J. Koller-Strametz Soluble selectins and the systemic inflammatory response syndrome after successful cardiopulmonary resuscitation Crit Care Med 28 2000 2360 2365
10. C.N. Sessler, A.C. Windsor, M. Schwartz, L. Watson, B.J. Fisher, and H.J. Sugerman Circulating ICAM-1 is increased in septic shock Am J Respir Crit Care Med 151 1995 1420 1427
11. H.C. Cowley, D. Heney, A.J. Gearing, I. Hemingway, and N.R. Webster Increased circulating adhesion molecule concentrations in patients with the systemic inflammatory response syndrome: a prospective cohort study Crit Care Med 22 1994 651 657
12. C.J. Cummings, C.N. Sessler, L.D. Beall, B.J. Fisher, A.M. Best, and A.A. Fowler III Soluble E-selectin levels in sepsis and critical illness. Correlation with infection and hemodynamic dysfunction Am J Respir Crit Care Med 156 1997 431 437
13. M. Hynninen, M. Valtonen, H. Markkanen, M. Vaara, P. Kuusela, and I. Jousela Interleukin 1 receptor antagonist and E-selectin concentrations: a comparison in patients with severe acute pancreatitis and severe sepsis J Crit Care 14 1999 63 68
14. P. Schuetz, A.E. Jones, W.C. Aird, and N.I. Shapiro Endothelial cell activation in emergency department patients with sepsis-related and non-sepsis-related hypotension Shock 36 2011 104 108
15. T. Gatheral, D.M. Reed, L. Moreno, P.J. Gough, B.J. Votta, and C.A. Sehon A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses PLoS One 7 2012 e42386
16. W. Wang, M. Deng, X. Liu, W. Ai, Q. Tang, and J. Hu TLR4 activation induces nontolerant inflammatory response in endothelial cells Inflammation 34 2011 509 518
17. E. Faure, L. Thomas, H. Xu, A. Medvedev, O. Equils, and M. Arditi Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation J Immunol 166 2001 2018 2024
18. I. Herzum, and H. Renz Inflammatory markers in SIRS, sepsis and septic shock Curr Med Chem 15 2008 581 587
19. T. Takakuwa, S. Endo, K. Inada, T. Kasai, Y. Yamada, and M. Ogawa Assessment of inflammatory cytokines, nitrate/nitrite, type II phospholipase A2, and soluble adhesion molecules in systemic inflammatory response syndrome Res Commun Mol Pathol Pharmacol 98 1997 43 52
20. J. Boldt, M. Muller, D. Kuhn, L.C. Linke, and G. Hempelmann Circulating adhesion molecules in the critically ill: a comparison between trauma and sepsis patients Intensive Care Med 22 1996 122 128
21. Y.Q. Hou, P. Xu, M. Zhang, D. Han, L. Peng, and D.Y. Liang Serum decoy receptor 3, a potential new biomarker for sepsis Clin Chim Acta 413 2012 744 748
22. C. Fitting, M. Parlato, M. dib-Conquy, N. Memain, F. Philippart, and B. Misset DNAemia detection by multiplex PCR and biomarkers for infection in systemic inflammatory response syndrome patients PLoS One 7 2012 e38916
23. S. Gando, T. Kameue, N. Matsuda, M. Hayakawa, H. Hoshino, and H. Kato Serial changes in neutrophil-endothelial activation markers during the course of sepsis associated with disseminated intravascular coagulation Thromb Res 116 2005 91 100
24. S. Kayal, J.P. Jais, N. Aguini, J. Chaudiere, and J. Labrousse Elevated circulating E-selectin, intercellular adhesion molecule 1, and von Willebrand factor in patients with severe infection Am J Respir Crit Care Med 157 1998 776 784
25. S. Knapp, F. Thalhammer, G.J. Locker, K. Laczika, U. Hollenstein, and M. Frass Prognostic value of MIP-1 alpha, TGF-beta 2, sELAM-1, and sVCAM-1 in patients with gram-positive sepsis Clin Immunol Immunopathol 87 1998 139 144
26. W. Newman, L.D. Beall, C.W. Carson, G.G. Hunder, N. Graben, and Z.I. Randhawa Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock J Immunol 150 1993 644 654
27. M.A. Weigand, H. Schmidt, M. Pourmahmoud, Q. Zhao, E. Martin, and H.J. Bardenheuer Circulating intercellular adhesion molecule-1 as an early predictor of hepatic failure in patients with septic shock Crit Care Med 27 1999 2656 2661
28. B.T. Qi, P. Wang, J. Li, H.X. Ren, and M. Xie Levels of soluble vascular cell adhesion molecule-1 and soluble intercellular adhesion molecule-2 in plasma of patients with hemorrhagic fever with renal syndrome, and significance of the changes in level Viral Immunol 19 2006 565 569
29. M.P. Bevilacqua, and R.M. Nelson Selectins J Clin Invest 91 1993 379 387
30. B. Jilma, A. Blann, T. Pernerstorfer, P. Stohlawetz, H.G. Eichler, and B. Vondrovec Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin Am J Respir Crit Care Med 159 1999 857 863
31. M. Leone, F. Garcin, W. Chaabane, B. Boutiere-Albanese, J. Albanese, and F. Dignat-Georges Activation of adhesion molecules in patients with septic shock Ann Fr Anesth Reanim 22 2003 721 729
32. S. Endo, K. Inada, T. Kasai, T. Takakuwa, Y. Yamada, and S. Koike Levels of soluble adhesion molecules and cytokines in patients with septic multiple organ failure J Inflamm 46 1995 212 219
33. B. Megarbane, P. Marchal, A. Marfaing-Koka, O. Belliard, F. Jacobs, and I. Chary Increased diffusion of soluble adhesion molecules in meningitis, severe sepsis and systemic inflammatory response without neurological infection is associated with intrathecal shedding in cases of meningitis Intensive Care Med 2004
34. B. Stoiser, S. Knapp, F. Thalhammer, G.J. Locker, J. Kofler, and U. Hollenstein Time course of immunological markers in patients with the systemic inflammatory response syndrome: evaluation of sCD14, sVCAM-1, sELAM-1, MIP-1 alpha and TGF-beta 2 Eur J Clin Invest 28 1998 672 678
35. J. Schroder, V. Kahlke, and K.H. Staubach Gender differences in human sepsis Arch Surg 133 1998 1200 1205
36. M.W. Wichmann, D. Inthorn, H.J. Andress, and F.W. Schildberg Incidence and mortality of severe sepsis in surgical intensive care patients: the influence of patient gender on disease process and outcome Intensive Care Med 26 2000 167 172
37. D. Andaluz-Ojeda, F. Bobillo, and V. Iglesias A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis Cytokine 57 2012 332 336
38. M. Rodriguez-Gaspar, F. Santolaria, and A. Jarque-Lopez Prognostic value of cytokines in SIRS general medical patients Cytokine 15 2001 232 236
39. R. De Pablo, J. Monserrat, and E. Reyes Mortality in patients with septic shock correlates with anti-inflammatory but not proinflammatory immunomodulatory molecules J Intensive Care Med 26 2011 125 132
40. C.E. Ventetuolo, and M.M. Levy Biomarkers: diagnosis and risk assessment in sepsis Clin Chest Med 29 2008 591 603
41. B.M. Tang, G.D. Eslick, J.C. Craig, and A.S. McLean Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis Lancet Infect Dis 7 2007 210 217
42. A.E. Jones, J.F. Fiechtl, M.D. Brown, J.J. Ballew, and J.A. Kline Procalcitonin test in the diagnosis of bacteremia: a meta-analysis Ann Emerg Med 50 2007 34 41
43. B. Uzzan, R. Cohen, P. Nicolas, M. Cucherat, and G.Y. Perret Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis Crit Care Med 34 2006 1996 2003
44. L. Simon, F. Gauvin, D.K. Amre, P. Saint-Louis, and J. Lacroix Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis Clin Infect Dis 39 2004 206 217
45. F. Stucker, F. Herrmann, J.D. Graf, J.P. Michel, K.H. Krause, and G. Gavazzi Procalcitonin and infection in elderly patients J Am Geriatr Soc 53 2005 1392 1395
46. T. Dwolatzky, K. Olshtain-Pops, A.M. Yinnon, D. Raveh, O. Rogowski, and I. Shapira Procalcitonin in the elderly: normal plasma concentrations and response to bacterial infections Eur J Clin Microbiol Infect Dis 24 2005 763 765
47. C. Pierrakos, and J.L. Vincent Sepsis biomarkers: a review Crit Care 14 2010 R15-
48. E. Presterl, A. Lassnigg, P. Mueller-Uri, C. Wenisch, I. El-Menyawi, and W. Graninger High serum laminin concentrations in patients with Candida sepsis Eur J Clin Invest 29 1999 992 996
49. A. Scherpereel, F. Depontieu, B. Grigoriu, B. Cavestri, A. Tsicopoulos, and T. Gentina Endocan, a new endothelial marker in human sepsis Crit Care Med 34 2006 532 537
50. G. Friedman, S. Jankowski, M. Shahla, M. Goldman, R.M. Rose, and R.J. Kahn Administration of an antibody to E-selectin in patients with septic shock Crit Care Med 24 1996 229 233