메뉴 건너뛰기




Volumn 65, Issue 1, 2013, Pages 132-138

Antiproliferative activity of the dietary isothiocyanate erucin, a bioactive compound from cruciferous vegetables, on human prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; ERUCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SULFORAPHANE;

EID: 84873726767     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2013.741747     Document Type: Article
Times cited : (42)

References (34)
  • 1
    • 76049128595 scopus 로고    scopus 로고
    • Estimates of cancer incidence and mortality in Europe in 2008
    • Ferlay J, Parkin DM, and Steliarova-Foucher E: Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 46, 765-781, 2010.
    • (2010) Eur J Cancer , vol.46 , pp. 765-781
    • Ferlay, J.1    Parkin, D.M.2    Steliarova-Foucher, E.3
  • 2
    • 49849087443 scopus 로고    scopus 로고
    • Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate
    • Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, et al.: Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS One 3, e2568, 2008
    • (2008) PLoS One , vol.3
    • Traka, M.1    Gasper, A.V.2    Melchini, A.3    Bacon, J.R.4    Needs, P.W.5
  • 3
    • 77954409309 scopus 로고    scopus 로고
    • The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer
    • Traka MH, Spinks CA, Doleman JF, Melchini A, Ball RY, et al.: The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer. Mol Cancer 13, 189, 2010.
    • (2010) Mol Cancer , vol.13 , pp. 189
    • Traka, M.H.1    Spinks, C.A.2    Doleman, J.F.3    Melchini, A.4    Ball, R.Y.5
  • 4
    • 70249140956 scopus 로고    scopus 로고
    • Dietary glucosinolate intake and risk of prostate cancer in the EPIC-Heidelberg cohort study
    • Steinbrecher A, Nimptsch K, Hüsing A, Rohrmann S, and Linseisen J: Dietary glucosinolate intake and risk of prostate cancer in the EPIC-Heidelberg cohort study. Int J Cancer 125, 2179-2186, 2009.
    • (2009) Int J Cancer , vol.125 , pp. 2179-2186
    • Steinbrecher, A.1    Nimptsch, K.2    Hüsing, A.3    Rohrmann, S.4    Linseisen, J.5
  • 5
    • 34247606510 scopus 로고    scopus 로고
    • Molecular basis for chemoprevention by sulforaphane: A comprehensive review
    • Juge N, Mithen RF, and Traka M: Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 64, 1105-1127, 2007.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 1105-1127
    • Juge, N.1    Mithen, R.F.2    Traka, M.3
  • 6
    • 79952079347 scopus 로고    scopus 로고
    • Biological profile of erucin: A new promising anticancer agent from cruciferous vegetables
    • Melchini A and Traka MH: Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables. Toxins 2, 593-612, 2010.
    • (2010) Toxins , vol.2 , pp. 593-612
    • Melchini, A.1    Traka, M.H.2
  • 7
    • 0014775920 scopus 로고
    • Isolation of 4-methylthiobutylglucosinolate (glucoerucin) from seeds of Eruca sativa Mill
    • Gmelin R and Schluter M: Isolation of 4-methylthiobutylglucosinolate (glucoerucin) from seeds of Eruca sativa Mill. Arch Pharm Ber Dtsch Pharm Ges 303, 330-334, 1970.
    • (1970) Arch Pharm Ber Dtsch Pharm Ges , vol.303 , pp. 330-334
    • Gmelin, R.1    Schluter, M.2
  • 8
    • 80054979844 scopus 로고    scopus 로고
    • Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design
    • Clarke JD, Hsu A, Riedl K, Bella D, Schwartz SJ, et al.: Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design. Pharmacol Res 64, 456-463, 2011.
    • (2011) Pharmacol Res , vol.64 , pp. 456-463
    • Clarke, J.D.1    Hsu, A.2    Riedl, K.3    Bella, D.4    Schwartz, S.J.5
  • 9
    • 0030781225 scopus 로고    scopus 로고
    • Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: Identification of phase i metabolites and glutathione conjugates
    • Kassahun K, Davis M, Hu P, Martin B, and Baillie T: Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates. Chem Res Toxicol 10, 1228-1233, 1997.
    • (1997) Chem Res Toxicol , vol.10 , pp. 1228-1233
    • Kassahun, K.1    Davis, M.2    Hu, P.3    Martin, B.4    Baillie, T.5
  • 10
    • 33746933154 scopus 로고    scopus 로고
    • Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids
    • Vermeulen M, van den Berg R, Freidig AP, van Bladeren PJ, and Vaes WH: Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids. J Agric Food Chem 54, 5350-5358, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 5350-5358
    • Vermeulen, M.1    Van Den Berg, R.2    Freidig, A.P.3    Van Bladeren, P.J.4    Vaes, W.H.5
  • 11
    • 67349224103 scopus 로고    scopus 로고
    • Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells
    • Melchini A, Costa C, Traka M, Miceli N, Mithen R, et al.: Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. Food Chem Toxicol 47, 1430-1436, 2009.
    • (2009) Food Chem Toxicol , vol.47 , pp. 1430-1436
    • Melchini, A.1    Costa, C.2    Traka, M.3    Miceli, N.4    Mithen, R.5
  • 12
    • 57649184041 scopus 로고    scopus 로고
    • Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane
    • Hanlon N, Coldham N, Sauer MJ, and Ioannides C: Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane. Chem Biol Interact 177, 115-120, 2009.
    • (2009) Chem Biol Interact , vol.177 , pp. 115-120
    • Hanlon, N.1    Coldham, N.2    Sauer, M.J.3    Ioannides, C.4
  • 13
    • 14644436340 scopus 로고    scopus 로고
    • Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells
    • Wang W, Wang S, Howie AF, Beckett GJ, Mithen R, et al.: Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells. J Agric Food Chem 53, 1417-1421, 2005.
    • (2005) J Agric Food Chem , vol.53 , pp. 1417-1421
    • Wang, W.1    Wang, S.2    Howie, A.F.3    Beckett, G.J.4    Mithen, R.5
  • 14
    • 19344367171 scopus 로고    scopus 로고
    • Role of PI3K/AKT and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells
    • Jakubikova J, Sedlak J, Mithen R, and Bao Y: Role of PI3K/AKT and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochem Pharmacol 69, 1543-1552, 2005.
    • (2005) Biochem Pharmacol , vol.69 , pp. 1543-1552
    • Jakubikova, J.1    Sedlak, J.2    Mithen, R.3    Bao, Y.4
  • 15
    • 10744222218 scopus 로고    scopus 로고
    • The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cellcycle progression and apoptosis induction of human leukemia cells
    • Fimognari C, Nusse M, Iori R, Cantelli-Forti G, and Hrelia P: The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cellcycle progression and apoptosis induction of human leukemia cells. Invest New Drugs 22, 119-129, 2004.
    • (2004) Invest New Drugs , vol.22 , pp. 119-129
    • Fimognari, C.1    Nusse, M.2    Iori, R.3    Cantelli-Forti, G.4    Hrelia, P.5
  • 16
    • 46549087553 scopus 로고    scopus 로고
    • Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (Hep G2) cells towards benzo(a)pyrene and their mode of action
    • Lamy E, Schröder J, Paulus S, Brenk P, Stahl T, et al.: Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (Hep G2) cells towards benzo(a)pyrene and their mode of action. Food Chem Toxicol 46, 2415-2421, 2008.
    • (2008) Food Chem Toxicol , vol.46 , pp. 2415-2421
    • Lamy, E.1    Schröder, J.2    Paulus, S.3    Brenk, P.4    Stahl, T.5
  • 17
    • 39849092746 scopus 로고    scopus 로고
    • Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines
    • Harris KE and Jeffery EH: Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines. J Nutr Biochem 19, 246-254, 2008.
    • (2008) J Nutr Biochem , vol.19 , pp. 246-254
    • Harris, K.E.1    Jeffery, E.H.2
  • 18
    • 30344459982 scopus 로고    scopus 로고
    • Dietary agents in the chemoprevention of prostate cancer
    • Shukla S and Gupta S: Dietary agents in the chemoprevention of prostate cancer. Nutr Cancer 53, 18-32, 2005.
    • (2005) Nutr Cancer , vol.53 , pp. 18-32
    • Shukla, S.1    Gupta, S.2
  • 19
    • 67650218497 scopus 로고    scopus 로고
    • Chemoprevention by isothiocyanates: Molecular basis of apoptosis induction
    • Nakamura Y: Chemoprevention by isothiocyanates: molecular basis of apoptosis induction. Forum Nutr 61, 170-181, 2009.
    • (2009) Forum Nutr , vol.61 , pp. 170-181
    • Nakamura, Y.1
  • 20
    • 77956544792 scopus 로고    scopus 로고
    • Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review)
    • Wang LG and Chiao JW: Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review). Int J Oncol 37, 533-539, 2010.
    • (2010) Int J Oncol , vol.37 , pp. 533-539
    • Wang, L.G.1    Chiao, J.W.2
  • 21
    • 48749118821 scopus 로고    scopus 로고
    • De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc
    • Wang LG, Liu XM, Fang Y, Dai W, Chiao FB, et al.: De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc. Int J Oncol 33, 375-380, 2008.
    • (2008) Int J Oncol , vol.33 , pp. 375-380
    • Wang, L.G.1    Liu, X.M.2    Fang, Y.3    Dai, W.4    Chiao, F.B.5
  • 22
    • 69449098702 scopus 로고    scopus 로고
    • Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure
    • Chambers KF, Bacon JR, Kemsley EK, Mills RD, Ball RY, et al.: Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure. Prostate 69, 1411-1421, 2009.
    • (2009) Prostate , vol.69 , pp. 1411-1421
    • Chambers, K.F.1    Bacon, J.R.2    Kemsley, E.K.3    Mills, R.D.4    Ball, R.Y.5
  • 23
    • 58149161379 scopus 로고    scopus 로고
    • Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21 (waf1/cip1)
    • Traka MH, Chambers KF, Lund EK, Goodlad RA, Johnson IT, et al.: Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21 (waf1/cip1). Nutr Cancer 61, 137-145, 2009.
    • (2009) Nutr Cancer , vol.61 , pp. 137-145
    • Traka, M.H.1    Chambers, K.F.2    Lund, E.K.3    Goodlad, R.A.4    Johnson, I.T.5
  • 24
    • 0034674712 scopus 로고    scopus 로고
    • The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
    • Zhang W, Geiman DE, Shields JM, Dang DT, Mahatan CS, et al.: The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J Biol Chem 275, 18391-18398, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 18391-18398
    • Zhang, W.1    Geiman, D.E.2    Shields, J.M.3    Dang, D.T.4    Mahatan, C.S.5
  • 25
    • 23244450241 scopus 로고    scopus 로고
    • Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane
    • Traka M, Gasper AV, Smith JA, Hawkey CJ, Bao Y, et al.: Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J Nutr 135, 1865-1872, 2005.
    • (2005) J Nutr , vol.135 , pp. 1865-1872
    • Traka, M.1    Gasper, A.V.2    Smith, J.A.3    Hawkey, C.J.4    Bao, Y.5
  • 26
    • 70349499022 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors
    • Jain L, Vargo CA, Danesi R, Sissung TM, Price DK, et al.: The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors. Mol Cancer Ther 8, 2496-2508, 2009.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2496-2508
    • Jain, L.1    Vargo, C.A.2    Danesi, R.3    Sissung, T.M.4    Price, D.K.5
  • 28
    • 65949119310 scopus 로고    scopus 로고
    • How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
    • Mebratu Y and Tesfaigzi Y: How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle 8, 1168-1175, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 1168-1175
    • Mebratu, Y.1    Tesfaigzi, Y.2
  • 29
    • 84934434788 scopus 로고    scopus 로고
    • Modulatory actions of neuropeptide y on prostate cancer growth: Role of MAP kinase/ERK 1/2 activation
    • Ruscica M, Dozio E, Motta M, and Magni P: Modulatory actions of neuropeptide Y on prostate cancer growth: role of MAP kinase/ERK 1/2 activation. Adv Exp Med Biol 604, 96-100, 2007.
    • (2007) Adv Exp Med Biol , vol.604 , pp. 96-100
    • Ruscica, M.1    Dozio, E.2    Motta, M.3    Magni, P.4
  • 30
    • 36048936602 scopus 로고    scopus 로고
    • Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2
    • Moro L, Arbini AA, Marra E, and Greco M: Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2. Int J Oncol 30, 217-224, 2007.
    • (2007) Int J Oncol , vol.30 , pp. 217-224
    • Moro, L.1    Arbini, A.A.2    Marra, E.3    Greco, M.4
  • 31
    • 77955072957 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappa B signal pathways
    • Yang MD, Lai KC, Lai TY, Hsu SC, Kuo CL, et al.: Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappa B signal pathways. Anticancer Res 30, 2135-2143, 2010.
    • (2010) Anticancer Res , vol.30 , pp. 2135-2143
    • Yang, M.D.1    Lai, K.C.2    Lai, T.Y.3    Hsu, S.C.4    Kuo, C.L.5
  • 32
    • 33748358379 scopus 로고    scopus 로고
    • Mechanism of action of isothiocyanates: The induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2
    • Xu C, Yuan X, Pan Z, Shen G, Kim JH, et al.: Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2. Mol Cancer Ther 5, 1918-1926, 2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1918-1926
    • Xu, C.1    Yuan, X.2    Pan, Z.3    Shen, G.4    Kim, J.H.5
  • 33
    • 33644865443 scopus 로고    scopus 로고
    • ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells
    • Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, et al.: ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells. Carcinogenesis 27, 437-445, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 437-445
    • Xu, C.1    Shen, G.2    Yuan, X.3    Kim, J.H.4    Gopalkrishnan, A.5
  • 34
    • 63049122191 scopus 로고    scopus 로고
    • MTBITC mediates cell cycle arrest and apoptosis induction in human Hep G2 cells despite its rapid degradation kinetics in the in vitro model
    • Lamy E and Mersch-Sundermann V: MTBITC mediates cell cycle arrest and apoptosis induction in human Hep G2 cells despite its rapid degradation kinetics in the in vitro model. Environ Mol Mutagen 50, 190-200, 2009.
    • (2009) Environ Mol Mutagen , vol.50 , pp. 190-200
    • Lamy, E.1    Mersch-Sundermann, V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.