-
1
-
-
76049128595
-
Estimates of cancer incidence and mortality in Europe in 2008
-
Ferlay J, Parkin DM, and Steliarova-Foucher E: Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 46, 765-781, 2010.
-
(2010)
Eur J Cancer
, vol.46
, pp. 765-781
-
-
Ferlay, J.1
Parkin, D.M.2
Steliarova-Foucher, E.3
-
2
-
-
49849087443
-
Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate
-
Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, et al.: Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS One 3, e2568, 2008
-
(2008)
PLoS One
, vol.3
-
-
Traka, M.1
Gasper, A.V.2
Melchini, A.3
Bacon, J.R.4
Needs, P.W.5
-
3
-
-
77954409309
-
The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer
-
Traka MH, Spinks CA, Doleman JF, Melchini A, Ball RY, et al.: The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer. Mol Cancer 13, 189, 2010.
-
(2010)
Mol Cancer
, vol.13
, pp. 189
-
-
Traka, M.H.1
Spinks, C.A.2
Doleman, J.F.3
Melchini, A.4
Ball, R.Y.5
-
4
-
-
70249140956
-
Dietary glucosinolate intake and risk of prostate cancer in the EPIC-Heidelberg cohort study
-
Steinbrecher A, Nimptsch K, Hüsing A, Rohrmann S, and Linseisen J: Dietary glucosinolate intake and risk of prostate cancer in the EPIC-Heidelberg cohort study. Int J Cancer 125, 2179-2186, 2009.
-
(2009)
Int J Cancer
, vol.125
, pp. 2179-2186
-
-
Steinbrecher, A.1
Nimptsch, K.2
Hüsing, A.3
Rohrmann, S.4
Linseisen, J.5
-
5
-
-
34247606510
-
Molecular basis for chemoprevention by sulforaphane: A comprehensive review
-
Juge N, Mithen RF, and Traka M: Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 64, 1105-1127, 2007.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1105-1127
-
-
Juge, N.1
Mithen, R.F.2
Traka, M.3
-
6
-
-
79952079347
-
Biological profile of erucin: A new promising anticancer agent from cruciferous vegetables
-
Melchini A and Traka MH: Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables. Toxins 2, 593-612, 2010.
-
(2010)
Toxins
, vol.2
, pp. 593-612
-
-
Melchini, A.1
Traka, M.H.2
-
7
-
-
0014775920
-
Isolation of 4-methylthiobutylglucosinolate (glucoerucin) from seeds of Eruca sativa Mill
-
Gmelin R and Schluter M: Isolation of 4-methylthiobutylglucosinolate (glucoerucin) from seeds of Eruca sativa Mill. Arch Pharm Ber Dtsch Pharm Ges 303, 330-334, 1970.
-
(1970)
Arch Pharm Ber Dtsch Pharm Ges
, vol.303
, pp. 330-334
-
-
Gmelin, R.1
Schluter, M.2
-
8
-
-
80054979844
-
Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design
-
Clarke JD, Hsu A, Riedl K, Bella D, Schwartz SJ, et al.: Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design. Pharmacol Res 64, 456-463, 2011.
-
(2011)
Pharmacol Res
, vol.64
, pp. 456-463
-
-
Clarke, J.D.1
Hsu, A.2
Riedl, K.3
Bella, D.4
Schwartz, S.J.5
-
9
-
-
0030781225
-
Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: Identification of phase i metabolites and glutathione conjugates
-
Kassahun K, Davis M, Hu P, Martin B, and Baillie T: Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates. Chem Res Toxicol 10, 1228-1233, 1997.
-
(1997)
Chem Res Toxicol
, vol.10
, pp. 1228-1233
-
-
Kassahun, K.1
Davis, M.2
Hu, P.3
Martin, B.4
Baillie, T.5
-
10
-
-
33746933154
-
Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids
-
Vermeulen M, van den Berg R, Freidig AP, van Bladeren PJ, and Vaes WH: Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids. J Agric Food Chem 54, 5350-5358, 2006.
-
(2006)
J Agric Food Chem
, vol.54
, pp. 5350-5358
-
-
Vermeulen, M.1
Van Den Berg, R.2
Freidig, A.P.3
Van Bladeren, P.J.4
Vaes, W.H.5
-
11
-
-
67349224103
-
Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells
-
Melchini A, Costa C, Traka M, Miceli N, Mithen R, et al.: Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. Food Chem Toxicol 47, 1430-1436, 2009.
-
(2009)
Food Chem Toxicol
, vol.47
, pp. 1430-1436
-
-
Melchini, A.1
Costa, C.2
Traka, M.3
Miceli, N.4
Mithen, R.5
-
12
-
-
57649184041
-
Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane
-
Hanlon N, Coldham N, Sauer MJ, and Ioannides C: Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane. Chem Biol Interact 177, 115-120, 2009.
-
(2009)
Chem Biol Interact
, vol.177
, pp. 115-120
-
-
Hanlon, N.1
Coldham, N.2
Sauer, M.J.3
Ioannides, C.4
-
13
-
-
14644436340
-
Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells
-
Wang W, Wang S, Howie AF, Beckett GJ, Mithen R, et al.: Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells. J Agric Food Chem 53, 1417-1421, 2005.
-
(2005)
J Agric Food Chem
, vol.53
, pp. 1417-1421
-
-
Wang, W.1
Wang, S.2
Howie, A.F.3
Beckett, G.J.4
Mithen, R.5
-
14
-
-
19344367171
-
Role of PI3K/AKT and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells
-
Jakubikova J, Sedlak J, Mithen R, and Bao Y: Role of PI3K/AKT and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochem Pharmacol 69, 1543-1552, 2005.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1543-1552
-
-
Jakubikova, J.1
Sedlak, J.2
Mithen, R.3
Bao, Y.4
-
15
-
-
10744222218
-
The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cellcycle progression and apoptosis induction of human leukemia cells
-
Fimognari C, Nusse M, Iori R, Cantelli-Forti G, and Hrelia P: The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cellcycle progression and apoptosis induction of human leukemia cells. Invest New Drugs 22, 119-129, 2004.
-
(2004)
Invest New Drugs
, vol.22
, pp. 119-129
-
-
Fimognari, C.1
Nusse, M.2
Iori, R.3
Cantelli-Forti, G.4
Hrelia, P.5
-
16
-
-
46549087553
-
Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (Hep G2) cells towards benzo(a)pyrene and their mode of action
-
Lamy E, Schröder J, Paulus S, Brenk P, Stahl T, et al.: Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (Hep G2) cells towards benzo(a)pyrene and their mode of action. Food Chem Toxicol 46, 2415-2421, 2008.
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 2415-2421
-
-
Lamy, E.1
Schröder, J.2
Paulus, S.3
Brenk, P.4
Stahl, T.5
-
17
-
-
39849092746
-
Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines
-
Harris KE and Jeffery EH: Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines. J Nutr Biochem 19, 246-254, 2008.
-
(2008)
J Nutr Biochem
, vol.19
, pp. 246-254
-
-
Harris, K.E.1
Jeffery, E.H.2
-
18
-
-
30344459982
-
Dietary agents in the chemoprevention of prostate cancer
-
Shukla S and Gupta S: Dietary agents in the chemoprevention of prostate cancer. Nutr Cancer 53, 18-32, 2005.
-
(2005)
Nutr Cancer
, vol.53
, pp. 18-32
-
-
Shukla, S.1
Gupta, S.2
-
19
-
-
67650218497
-
Chemoprevention by isothiocyanates: Molecular basis of apoptosis induction
-
Nakamura Y: Chemoprevention by isothiocyanates: molecular basis of apoptosis induction. Forum Nutr 61, 170-181, 2009.
-
(2009)
Forum Nutr
, vol.61
, pp. 170-181
-
-
Nakamura, Y.1
-
20
-
-
77956544792
-
Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review)
-
Wang LG and Chiao JW: Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review). Int J Oncol 37, 533-539, 2010.
-
(2010)
Int J Oncol
, vol.37
, pp. 533-539
-
-
Wang, L.G.1
Chiao, J.W.2
-
21
-
-
48749118821
-
De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc
-
Wang LG, Liu XM, Fang Y, Dai W, Chiao FB, et al.: De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc. Int J Oncol 33, 375-380, 2008.
-
(2008)
Int J Oncol
, vol.33
, pp. 375-380
-
-
Wang, L.G.1
Liu, X.M.2
Fang, Y.3
Dai, W.4
Chiao, F.B.5
-
22
-
-
69449098702
-
Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure
-
Chambers KF, Bacon JR, Kemsley EK, Mills RD, Ball RY, et al.: Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure. Prostate 69, 1411-1421, 2009.
-
(2009)
Prostate
, vol.69
, pp. 1411-1421
-
-
Chambers, K.F.1
Bacon, J.R.2
Kemsley, E.K.3
Mills, R.D.4
Ball, R.Y.5
-
23
-
-
58149161379
-
Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21 (waf1/cip1)
-
Traka MH, Chambers KF, Lund EK, Goodlad RA, Johnson IT, et al.: Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21 (waf1/cip1). Nutr Cancer 61, 137-145, 2009.
-
(2009)
Nutr Cancer
, vol.61
, pp. 137-145
-
-
Traka, M.H.1
Chambers, K.F.2
Lund, E.K.3
Goodlad, R.A.4
Johnson, I.T.5
-
24
-
-
0034674712
-
The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
-
Zhang W, Geiman DE, Shields JM, Dang DT, Mahatan CS, et al.: The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J Biol Chem 275, 18391-18398, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 18391-18398
-
-
Zhang, W.1
Geiman, D.E.2
Shields, J.M.3
Dang, D.T.4
Mahatan, C.S.5
-
25
-
-
23244450241
-
Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane
-
Traka M, Gasper AV, Smith JA, Hawkey CJ, Bao Y, et al.: Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J Nutr 135, 1865-1872, 2005.
-
(2005)
J Nutr
, vol.135
, pp. 1865-1872
-
-
Traka, M.1
Gasper, A.V.2
Smith, J.A.3
Hawkey, C.J.4
Bao, Y.5
-
26
-
-
70349499022
-
The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors
-
Jain L, Vargo CA, Danesi R, Sissung TM, Price DK, et al.: The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors. Mol Cancer Ther 8, 2496-2508, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2496-2508
-
-
Jain, L.1
Vargo, C.A.2
Danesi, R.3
Sissung, T.M.4
Price, D.K.5
-
27
-
-
74949130915
-
TGF-beta signalling and immunity in prostate tumourigenesis
-
Diener KR, Need EF, Buchanan G, and Hayball JD: TGF-beta signalling and immunity in prostate tumourigenesis. Expert Opin Ther Targets 14, 179-192, 2010.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 179-192
-
-
Diener, K.R.1
Need, E.F.2
Buchanan, G.3
Hayball, J.D.4
-
28
-
-
65949119310
-
How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
-
Mebratu Y and Tesfaigzi Y: How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle 8, 1168-1175, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 1168-1175
-
-
Mebratu, Y.1
Tesfaigzi, Y.2
-
29
-
-
84934434788
-
Modulatory actions of neuropeptide y on prostate cancer growth: Role of MAP kinase/ERK 1/2 activation
-
Ruscica M, Dozio E, Motta M, and Magni P: Modulatory actions of neuropeptide Y on prostate cancer growth: role of MAP kinase/ERK 1/2 activation. Adv Exp Med Biol 604, 96-100, 2007.
-
(2007)
Adv Exp Med Biol
, vol.604
, pp. 96-100
-
-
Ruscica, M.1
Dozio, E.2
Motta, M.3
Magni, P.4
-
30
-
-
36048936602
-
Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2
-
Moro L, Arbini AA, Marra E, and Greco M: Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2. Int J Oncol 30, 217-224, 2007.
-
(2007)
Int J Oncol
, vol.30
, pp. 217-224
-
-
Moro, L.1
Arbini, A.A.2
Marra, E.3
Greco, M.4
-
31
-
-
77955072957
-
Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappa B signal pathways
-
Yang MD, Lai KC, Lai TY, Hsu SC, Kuo CL, et al.: Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappa B signal pathways. Anticancer Res 30, 2135-2143, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 2135-2143
-
-
Yang, M.D.1
Lai, K.C.2
Lai, T.Y.3
Hsu, S.C.4
Kuo, C.L.5
-
32
-
-
33748358379
-
Mechanism of action of isothiocyanates: The induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2
-
Xu C, Yuan X, Pan Z, Shen G, Kim JH, et al.: Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2. Mol Cancer Ther 5, 1918-1926, 2006.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1918-1926
-
-
Xu, C.1
Yuan, X.2
Pan, Z.3
Shen, G.4
Kim, J.H.5
-
33
-
-
33644865443
-
ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells
-
Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, et al.: ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells. Carcinogenesis 27, 437-445, 2006.
-
(2006)
Carcinogenesis
, vol.27
, pp. 437-445
-
-
Xu, C.1
Shen, G.2
Yuan, X.3
Kim, J.H.4
Gopalkrishnan, A.5
-
34
-
-
63049122191
-
MTBITC mediates cell cycle arrest and apoptosis induction in human Hep G2 cells despite its rapid degradation kinetics in the in vitro model
-
Lamy E and Mersch-Sundermann V: MTBITC mediates cell cycle arrest and apoptosis induction in human Hep G2 cells despite its rapid degradation kinetics in the in vitro model. Environ Mol Mutagen 50, 190-200, 2009.
-
(2009)
Environ Mol Mutagen
, vol.50
, pp. 190-200
-
-
Lamy, E.1
Mersch-Sundermann, V.2
|