Inhibition of monoamine oxidase by phthalide analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1269-1273

  Strydom, Belinda ^a   Bergh, Jacobus J ^a   Petzer, Jacobus P ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

Author keywords

2 Benzofuran 1(3H) one; MAO B; Monoamine oxidase; Phthalide; Reversible inhibition; Structure activity relationship

Indexed keywords

6 BENZYLOXYPHTHALIDE; [2 BENZOFURAN 1(3H) ONE]; AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; ISATIN; MONOAMINE OXIDASE INHIBITOR; PHENYL GROUP; PHTHALIDE DERIVATIVE; PHTHALIMIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

BENZOFURANS; BINDING SITES; HUMANS; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873725851     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.01.003     Document Type: Article

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