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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1519-1521

Synthesis and biological evaluation of 5-nitropyrimidine analogs with azabicyclic substituents as GPR119 agonists

(5) Yang, Zunhua a,b Fang, Yuanying a Pham, Tuan Anh N a Lee, Jongkook a Park, Haeil a

a Kangwon National University (South Korea)

b JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (China)

Author keywords

5 Nitropyrimidines; Azabicyclic alcohols; Azabicyclic amines; GPR119 agonist; Type 2 diabetes

Indexed keywords

APD 668; APS 668; AR 231453; GUANIDINE DERIVATIVE; PSN 632408; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS;

AZABICYCLO COMPOUNDS; DIABETES MELLITUS, TYPE 2; HUMANS; MOLECULAR CONFORMATION; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873723761 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.12.011 Document Type: Article

Times cited : (23)

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