Precipitation and stabilization of ultrafine particles of Fenofibrate in aqueous suspensions by RESOLV

Powder Technology

Volumn 236, Issue , 2013, Pages 75-84

  Dalvi, Sameer V ^a   Azad, Mohammad A ^a   Dave, Rajesh ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Fenofibrate; Precipitation; Rapid Expansion; Stabilization; Supercritical; Surfactants

Indexed keywords

AQUEOUS SUSPENSIONS; AVERAGE PARTICLE SIZE; ELECTROSTATIC STABILIZATION; FENOFIBRATE; HIGH DRUG LOADINGS; HYDROXYPROPYL METHYL CELLULOSE; PARTICLE CONCENTRATIONS; PARTICLE GROWTH; PARTICLE SIZE AND ITS DISTRIBUTION; PLURONIC F-68; POLY-LACTIDE-CO-GLYCOLIDE; POLYMERIC STABILIZERS; POORLY WATER-SOLUBLE DRUGS; RAPID EXPANSION; RAPID EXPANSION OF SUPERCRITICAL SOLUTIONS; STERIC STABILIZATION; SUPERCRITICAL; SUPERCRITICAL SOLUTION; SUSPENSION CONCENTRATIONS; SYNERGISTIC EFFECT; TWEEN 80; ULTRAFINE PARTICLE;

AGGLOMERATION; CARBON DIOXIDE; COPOLYMERS; HYDROGELS; LASERS; PARTICLE SIZE; PRECIPITATION (CHEMICAL); SODIUM ALGINATE; SODIUM DODECYL SULFATE; STABILIZATION; SURFACE ACTIVE AGENTS;

SUSPENSIONS (FLUIDS);

ALGINIC ACID; CARBON DIOXIDE; DODECYL SULFATE SODIUM; FENOFIBRATE; HYDROXYPROPYLMETHYLCELLULOSE; LIQUID SOLVENT; POLOXAMER; POLYGLACTIN; POLYSORBATE 80; SOLVENT; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); DRUG FORMULATION; DRUG STABILITY; DRUG STRUCTURE; GROWTH INHIBITION; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRECIPITATION; STATIC ELECTRICITY; SUPERCRITICAL FLUID; SUSPENSION;

EID: 84873715321     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.05.038     Document Type: Article

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