Melatonin treatment protects liver of Zucker rats after ischemia/reperfusion by diminishing oxidative stress and apoptosis

European Journal of Pharmacology

Volumn 701, Issue 1-3, 2013, Pages 185-193

  Kireev, Roman ^a   Bitoun, Samuel ^d   Cuesta, Sara ^a   Tejerina, Alejandro ^c   Ibarrola, Carolina ^b   Moreno, Enrique ^b   Vara, Elena ^a   Tresguerres, Jesus A F ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^c Tejerina Foundation   (Spain)

^d SORBONNE UNIVERSITÉ   (France)

Author keywords

(Zucker rat); Apoptosis; DNA fragmentation; Ischemia reperfusion; Melatonin; Oxidative stress; Steatotic liver

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ALKENE DERIVATIVE; ASPARTATE AMINOTRANSFERASE; CASPASE 9; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE TRANSFERASE; HYDROXYALKENE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MELATONIN; NITRIC OXIDE; PLACEBO; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; DNA FRAGMENTATION; DRUG RESPONSE; ENZYME ACTIVITY; EXPERIMENTAL RAT; FATTY LIVER; LIPID PEROXIDATION; LIVER FUNCTION; LIVER ISCHEMIA; LIVER PROTECTION; METABOLITE; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; REPERFUSION INJURY; SHAM PROCEDURE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 9; DNA FRAGMENTATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE DISULFIDE; LIPID PEROXIDATION; LIVER; MALE; MELATONIN; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; RATS; RATS, ZUCKER; REPERFUSION INJURY;

EID: 84873714923     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.11.038     Document Type: Article

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