Sodium nitroprusside decreased leukotriene C4 generation by inhibiting leukotriene C4 synthase expression and activity in hepatic ischemia-reperfusion injured rats

Biochemical Pharmacology

Volumn 73, Issue 5, 2007, Pages 724-735

  Yang, Shu Long ^a,b   Lou, Yi Jia ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b NANCHANG UNIVERSITY   (China)

Author keywords

Cysteinyl leukotrienes; Ischemia reperfusion injury; Leukotriene C4 synthase; Liver; Microsomal glutathione S transferase; Nitric oxide; Sodium nitroprusside

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE TRANSFERASE M2; GLUTATHIONE TRANSFERASE M3; INDUCIBLE NITRIC OXIDE SYNTHASE; LEUKOTRIENE C4; LEUKOTRIENE C4 SYNTHASE; MESSENGER RNA; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; IMMUNOBLOTTING; LIVER; LIVER ISCHEMIA; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE TRANSFERASE; LEUKOTRIENE C4; LIVER; LIVER DISEASES; MALE; NITRIC OXIDE DONORS; NITROPRUSSIDE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RNA, MESSENGER; TIME FACTORS;

EID: 33846531796     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.11.011     Document Type: Article

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