Deoxynivalenol induces ectodomain shedding of TNF receptor 1 and thereby inhibits the TNF-α-induced NF-κB signaling pathway

European Journal of Pharmacology

Volumn 701, Issue 1-3, 2013, Pages 144-151

  Hirano, Seiya ^a   Kataoka, Takao ^a  

^a KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Deoxynivalenol; ERK; p38 MAP kinase; TNF receptor 1; TNF converting enzyme; Trichothecene mycotoxin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 3 ACETYLDEOXYNIVALENOL; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADAM PROTEIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYCOTOXIN; PROTEIN ADAM17; T 2 TOXIN; TAPI 2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; VERRUCARIN A; VOMITOXIN;

ARTICLE; CARCINOMA CELL; CELL LYSATE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1ALPHA; MYCOTOXINS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TRICHOTHECENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84873713291     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.01.019     Document Type: Article

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