메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages

Neonatal Exendin-4 Reduces Growth, Fat Deposition and Glucose Tolerance during Treatment in the Intrauterine Growth-Restricted Lamb

Author keywords

[No Author keywords available]

Indexed keywords

EXENDIN 4;

EID: 84873704687     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056553     Document Type: Article
Times cited : (17)

References (85)
  • 1
    • 0038192201 scopus 로고    scopus 로고
    • Is birth weight related to later glucose and insulin metabolism?-a systematic review
    • Newsome CA, Shiell AW, Fall CHD, Phillips DIW, Shier R, et al. (2003) Is birth weight related to later glucose and insulin metabolism?-a systematic review. Diab Med 20: 339-348.
    • (2003) Diab Med , vol.20 , pp. 339-348
    • Newsome, C.A.1    Shiell, A.W.2    Fall, C.H.D.3    Phillips, D.I.W.4    Shier, R.5
  • 2
    • 58149234293 scopus 로고    scopus 로고
    • Birth weight and risk of type 2 diabetes: A systematic review
    • Whincup PH, Kaye SJ, Owen CG, Huxley R, Cook DG, et al. (2008) Birth weight and risk of type 2 diabetes: A systematic review. JAMA 300: 2886-2897.
    • (2008) JAMA , vol.300 , pp. 2886-2897
    • Whincup, P.H.1    Kaye, S.J.2    Owen, C.G.3    Huxley, R.4    Cook, D.G.5
  • 4
    • 1242295278 scopus 로고    scopus 로고
    • Birth weight and cardiovascular risk factors in a cohort followed until 80 years of age: the study of men born in 1913
    • Eriksson M, Wallander MA, Krakau I, Wedel H, Svardsudd K, (2004) Birth weight and cardiovascular risk factors in a cohort followed until 80 years of age: the study of men born in 1913. J Internal Med 255: 236-246.
    • (2004) J Internal Med , vol.255 , pp. 236-246
    • Eriksson, M.1    Wallander, M.A.2    Krakau, I.3    Wedel, H.4    Svardsudd, K.5
  • 5
    • 0036227764 scopus 로고    scopus 로고
    • Early differential defects of insulin secretion and action in 19-year-old Caucasian men who had low birth weight
    • Jensen CB, Storgaard H, Dela F, Holst JJ, Madsbad S, et al. (2002) Early differential defects of insulin secretion and action in 19-year-old Caucasian men who had low birth weight. Diabetes 51: 1271-1280.
    • (2002) Diabetes , vol.51 , pp. 1271-1280
    • Jensen, C.B.1    Storgaard, H.2    Dela, F.3    Holst, J.J.4    Madsbad, S.5
  • 6
    • 0038692038 scopus 로고    scopus 로고
    • β-cell capacity and insulin sensitivity in prepubertal children born small for gestational age: Influence of body size during childhood
    • Veening MA, van Weissenbruch MM, Heine RJ, Delemarre-van de Waal HA, (2003) β-cell capacity and insulin sensitivity in prepubertal children born small for gestational age: Influence of body size during childhood. Diabetes 52: 1756-1760.
    • (2003) Diabetes , vol.52 , pp. 1756-1760
    • Veening, M.A.1    van Weissenbruch, M.M.2    Heine, R.J.3    Delemarre-van de Waal, H.A.4
  • 7
    • 28444482424 scopus 로고    scopus 로고
    • Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children
    • Mericq V, Ong KK, Bazaes R, Peña V, Avila A, et al. (2005) Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children. Diabetologia 48: 2609-2614.
    • (2005) Diabetologia , vol.48 , pp. 2609-2614
    • Mericq, V.1    Ong, K.K.2    Bazaes, R.3    Peña, V.4    Avila, A.5
  • 8
    • 0001910201 scopus 로고    scopus 로고
    • Pathophysiology of intrauterine growth failure
    • In: Gluckman PD, Heymann MA, editors, 2 ed. London Arnold
    • Robinson JS, Owens JA (1996) Pathophysiology of intrauterine growth failure. In: Gluckman PD, Heymann MA, editors. Pediatrics and Perinatology The Scientific Basis. 2 ed. London Arnold.pp. 290-297.
    • (1996) Pediatrics and Perinatology The Scientific Basis , pp. 290-297
    • Robinson, J.S.1    Owens, J.A.2
  • 9
    • 33847069270 scopus 로고    scopus 로고
    • Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb
    • De Blasio MJ, Gatford KL, McMillen IC, Robinson JS, Owens JA, (2007) Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb. Endocrinology 148: 1350-1358.
    • (2007) Endocrinology , vol.148 , pp. 1350-1358
    • De Blasio, M.J.1    Gatford, K.L.2    McMillen, I.C.3    Robinson, J.S.4    Owens, J.A.5
  • 10
    • 33846781645 scopus 로고    scopus 로고
    • Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity, and adiposity in the young lamb
    • De Blasio MJ, Gatford KL, Robinson JS, Owens JA, (2007) Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity, and adiposity in the young lamb. Am J Physiol Regul Integr Comp Physiol 292: R875-886.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • De Blasio, M.J.1    Gatford, K.L.2    Robinson, J.S.3    Owens, J.A.4
  • 12
    • 53249129274 scopus 로고    scopus 로고
    • Impaired β-cell function and inadequate compensatory increases in β-cell mass after intrauterine growth restriction in sheep
    • Gatford KL, Mohammad SNB, Harland ML, De Blasio MJ, Fowden AL, et al. (2008) Impaired β-cell function and inadequate compensatory increases in β-cell mass after intrauterine growth restriction in sheep. Endocrinology 149: 5118-5127.
    • (2008) Endocrinology , vol.149 , pp. 5118-5127
    • Gatford, K.L.1    Mohammad, S.N.B.2    Harland, M.L.3    De Blasio, M.J.4    Fowden, A.L.5
  • 13
    • 0035489035 scopus 로고    scopus 로고
    • Intrauterine growth retardation leads to the development of type 2 diabetes in the rat
    • Simmons RA, Templeton LJ, Gertz SJ, (2001) Intrauterine growth retardation leads to the development of type 2 diabetes in the rat. Diabetes 50: 2279-2286.
    • (2001) Diabetes , vol.50 , pp. 2279-2286
    • Simmons, R.A.1    Templeton, L.J.2    Gertz, S.J.3
  • 14
    • 23344432499 scopus 로고    scopus 로고
    • Progressive accumulation of mitochondrial DNA mutations and decline in mitochondrial function lead to β-cell failure
    • Simmons RA, Suponitsky-Kroyter I, Selak MA, (2005) Progressive accumulation of mitochondrial DNA mutations and decline in mitochondrial function lead to β-cell failure. J Biol Chem 280: 28785-28791.
    • (2005) J Biol Chem , vol.280 , pp. 28785-28791
    • Simmons, R.A.1    Suponitsky-Kroyter, I.2    Selak, M.A.3
  • 15
    • 0037341252 scopus 로고    scopus 로고
    • Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat
    • Stoffers DA, Desai BM, DeLeon DD, Simmons RA, (2003) Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat. Diabetes 52: 734-740.
    • (2003) Diabetes , vol.52 , pp. 734-740
    • Stoffers, D.A.1    Desai, B.M.2    DeLeon, D.D.3    Simmons, R.A.4
  • 16
    • 80054098357 scopus 로고    scopus 로고
    • Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx-1 in the intrauterine growth retarded rat
    • Pinney S, Jaeckle Santos L, Han Y, Stoffers D, Simmons R, (2011) Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx-1 in the intrauterine growth retarded rat. Diabetologia 54: 2606-2614.
    • (2011) Diabetologia , vol.54 , pp. 2606-2614
    • Pinney, S.1    Jaeckle Santos, L.2    Han, Y.3    Stoffers, D.4    Simmons, R.5
  • 17
    • 15444373040 scopus 로고    scopus 로고
    • Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis
    • Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, et al. (2005) Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis. Am J Physiol Endocrinol Metab 288: E707-714.
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Brissova, M.1    Blaha, M.2    Spear, C.3    Nicholson, W.4    Radhika, A.5
  • 18
    • 9644268967 scopus 로고    scopus 로고
    • PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance
    • Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, et al. (2004) PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest 114: E828-836.
    • (2004) J Clin Invest , vol.114
    • Kulkarni, R.N.1    Jhala, U.S.2    Winnay, J.N.3    Krajewski, S.4    Montminy, M.5
  • 19
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park JH, Stoffers DA, Nicholls RD, Simmons RA, (2008) Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest 118: E2316-2324.
    • (2008) J Clin Invest , vol.118
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 20
    • 0023831257 scopus 로고
    • Ontogenic development of peptide hormones in the mammalian fetal pancreas
    • Reddy S, Elliott RB, (1988) Ontogenic development of peptide hormones in the mammalian fetal pancreas. Experientia 44: E1-9.
    • (1988) Experientia , vol.44
    • Reddy, S.1    Elliott, R.B.2
  • 21
    • 0033853921 scopus 로고    scopus 로고
    • β-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy
    • Kassem SA, Ariel I, Thornton PS, Scheimberg I, Glaser B, (2000) β-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy. Diabetes 49: 1325-1333.
    • (2000) Diabetes , vol.49 , pp. 1325-1333
    • Kassem, S.A.1    Ariel, I.2    Thornton, P.S.3    Scheimberg, I.4    Glaser, B.5
  • 23
    • 17844371675 scopus 로고    scopus 로고
    • Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction
    • Limesand SW, Jensen J, Hutton JC, Hay WW Jr, (2005) Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol 288: R1297-1305.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Limesand, S.W.1    Jensen, J.2    Hutton, J.C.3    Hay Jr., W.W.4
  • 24
    • 0023872502 scopus 로고
    • Maturation of insulin response to glucose during human fetal and neonatal development. Studies with perifusion of pancreatic isletlike cell clusters
    • Otonkoski T, Andersson S, Knip M, O S, (1988) Maturation of insulin response to glucose during human fetal and neonatal development. Studies with perifusion of pancreatic isletlike cell clusters. Diabetes 37: 286-291.
    • (1988) Diabetes , vol.37 , pp. 286-291
    • Otonkoski, T.1    Andersson, S.2    Knip, M.3
  • 25
    • 0017612447 scopus 로고
    • Glucagon, insulin and glucose homeostasis in the fetal lamb
    • Bassett JM, (1977) Glucagon, insulin and glucose homeostasis in the fetal lamb. Ann Rech Vet 8: 362-373.
    • (1977) Ann Rech Vet , vol.8 , pp. 362-373
    • Bassett, J.M.1
  • 26
    • 0019206790 scopus 로고
    • Effects of arginine and glucose on the release of insulin in the sheep fetus
    • Fowden AL, (1980) Effects of arginine and glucose on the release of insulin in the sheep fetus. J Endocrinol 87: E293-301.
    • (1980) J Endocrinol , vol.87
    • Fowden, A.L.1
  • 27
    • 33745814724 scopus 로고    scopus 로고
    • Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect
    • Rozance PJ, Limesand SW, Hay WW, (2006) Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect. Am J Physiol Endocrinol Metab 291: E404-E411.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Rozance, P.J.1    Limesand, S.W.2    Hay, W.W.3
  • 28
    • 0030903840 scopus 로고    scopus 로고
    • Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat
    • Scaglia L, Cahill CJ, Finegood DT, Bonner-Weir S, (1997) Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 138: 1736-1741.
    • (1997) Endocrinology , vol.138 , pp. 1736-1741
    • Scaglia, L.1    Cahill, C.J.2    Finegood, D.T.3    Bonner-Weir, S.4
  • 29
    • 0031788728 scopus 로고    scopus 로고
    • Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor
    • Petrik J, Arany E, McDonald TJ, Hill DJ, (1998) Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor. Endocrinology 139: 2994-3004.
    • (1998) Endocrinology , vol.139 , pp. 2994-3004
    • Petrik, J.1    Arany, E.2    McDonald, T.J.3    Hill, D.J.4
  • 30
    • 0033305240 scopus 로고    scopus 로고
    • A low protein diet alters the balance of islet cell replication and apoptosis in the fetal and neonatal rat and is associated with a reduced pancreatic expression of insulin-like growth factor-II
    • Petrik J, Reusens B, Arany E, Remacle C, Coelho C, et al. (1999) A low protein diet alters the balance of islet cell replication and apoptosis in the fetal and neonatal rat and is associated with a reduced pancreatic expression of insulin-like growth factor-II. Endocrinology 140: 4861-4873.
    • (1999) Endocrinology , vol.140 , pp. 4861-4873
    • Petrik, J.1    Reusens, B.2    Arany, E.3    Remacle, C.4    Coelho, C.5
  • 31
    • 34047213601 scopus 로고    scopus 로고
    • Physiological development of insulin secretion, calcium channels, and GLUT2 expression of pancreatic rat β-cells
    • Navarro-Tableros V, Fiordelisio T, Hernández-Cruz A, Hiriart M, (2007) Physiological development of insulin secretion, calcium channels, and GLUT2 expression of pancreatic rat β-cells. Am J Physiol Endocrinol Metab 292: E1018-E1029.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Navarro-Tableros, V.1    Fiordelisio, T.2    Hernández-Cruz, A.3    Hiriart, M.4
  • 32
    • 0036787347 scopus 로고    scopus 로고
    • Role of NADH shuttles in glucose-induced insulin secretion from fetal β-cells
    • Tan C, Tuch BE, Tu J, Brown SA, (2002) Role of NADH shuttles in glucose-induced insulin secretion from fetal β-cells. Diabetes 51: 2989-2996.
    • (2002) Diabetes , vol.51 , pp. 2989-2996
    • Tan, C.1    Tuch, B.E.2    Tu, J.3    Brown, S.A.4
  • 33
    • 27844580511 scopus 로고    scopus 로고
    • National Health and Medical Research Council of Australia, 7th edition. Canberra: Australian Government Publishing Service
    • National Health and Medical Research Council of Australia (2004) Australian code of practice for the care and use of animals for scientific purposes, 7th edition. Canberra: Australian Government Publishing Service. 82 p.
    • (2004) Australian code of practice for the care and use of animals for scientific purposes , pp. 82
  • 34
    • 0020789459 scopus 로고
    • The intake of milk by suckled, newborn lambs and the effects of twinning and cold exposure
    • Thompson GE, (1983) The intake of milk by suckled, newborn lambs and the effects of twinning and cold exposure. British J Nutr 50: 151-156.
    • (1983) British J Nutr , vol.50 , pp. 151-156
    • Thompson, G.E.1
  • 36
    • 32644433563 scopus 로고    scopus 로고
    • Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction
    • Limesand SW, Rozance PJ, Zerbe GO, Hutton JC, Hay WW Jr, (2006) Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. Endocrinology 147: 1488-1497.
    • (2006) Endocrinology , vol.147 , pp. 1488-1497
    • Limesand, S.W.1    Rozance, P.J.2    Zerbe, G.O.3    Hutton, J.C.4    Hay Jr., W.W.5
  • 37
    • 57649192347 scopus 로고    scopus 로고
    • Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity
    • Cabou C, Campistron G, Marsollier N, Leloup C, Cruciani-Guglielmacci C, et al. (2008) Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity. Diabetes 57: 2577-2587.
    • (2008) Diabetes , vol.57 , pp. 2577-2587
    • Cabou, C.1    Campistron, G.2    Marsollier, N.3    Leloup, C.4    Cruciani-Guglielmacci, C.5
  • 38
    • 80052903104 scopus 로고    scopus 로고
    • Brain GLP-1 signaling regulates femoral artery blood flow and insulin sensitivity through hypothalamic PKC-δ
    • Cabou C, Vachoux C, Campistron G, Drucker DJ, Burcelin R, (2011) Brain GLP-1 signaling regulates femoral artery blood flow and insulin sensitivity through hypothalamic PKC-δ. Diabetes 60: 2245-2256.
    • (2011) Diabetes , vol.60 , pp. 2245-2256
    • Cabou, C.1    Vachoux, C.2    Campistron, G.3    Drucker, D.J.4    Burcelin, R.5
  • 40
    • 33847069270 scopus 로고    scopus 로고
    • Placental restriction of fetal growth increases insulin action, growth and adiposity in the young lamb
    • De Blasio MJ, Gatford KL, McMillen IC, Robinson JS, Owens JA, (2007) Placental restriction of fetal growth increases insulin action, growth and adiposity in the young lamb. Endocrinology 148: 1350-1358.
    • (2007) Endocrinology , vol.148 , pp. 1350-1358
    • De Blasio, M.J.1    Gatford, K.L.2    McMillen, I.C.3    Robinson, J.S.4    Owens, J.A.5
  • 41
    • 0034620969 scopus 로고    scopus 로고
    • Association between postnatal catch-up growth and obesity in childhood: prospective cohort study
    • Ong KKL, Ahmed ML, Emmett PM, Preece MA, Dunger DB, (2000) Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. British Medical Journal 320: 967-971.
    • (2000) British Medical Journal , vol.320 , pp. 967-971
    • Ong, K.K.L.1    Ahmed, M.L.2    Emmett, P.M.3    Preece, M.A.4    Dunger, D.B.5
  • 42
    • 45549108351 scopus 로고    scopus 로고
    • Placental restriction of fetal growth decreases IGF1 and leptin mRNA expression in the perirenal adipose tissue of late gestation fetal sheep
    • Duffield JA, Vuocolo T, Tellam R, Yuen BS, Muhlhausler BS, et al. (2008) Placental restriction of fetal growth decreases IGF1 and leptin mRNA expression in the perirenal adipose tissue of late gestation fetal sheep. American Journal of Physiology 294: R1413-R1419.
    • (2008) American Journal of Physiology , vol.294
    • Duffield, J.A.1    Vuocolo, T.2    Tellam, R.3    Yuen, B.S.4    Muhlhausler, B.S.5
  • 43
    • 70149124598 scopus 로고    scopus 로고
    • Intrauterine growth restriction and the sex specific programming of leptin and peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA expression in visceral fat in the lamb
    • Duffield JA, Vuocolo T, Tellam R, McFarlane JR, Kauter KG, et al. (2009) Intrauterine growth restriction and the sex specific programming of leptin and peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA expression in visceral fat in the lamb. Pediatric Research 66: 59-65.
    • (2009) Pediatric Research , vol.66 , pp. 59-65
    • Duffield, J.A.1    Vuocolo, T.2    Tellam, R.3    McFarlane, J.R.4    Kauter, K.G.5
  • 44
  • 45
    • 28444482424 scopus 로고    scopus 로고
    • Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children
    • Mericq V, Ong KK, Bazaes R, Pena V, Avila A, et al. (2005) Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children. Diabetologia 48: 2609-2614.
    • (2005) Diabetologia , vol.48 , pp. 2609-2614
    • Mericq, V.1    Ong, K.K.2    Bazaes, R.3    Pena, V.4    Avila, A.5
  • 46
    • 69949085890 scopus 로고    scopus 로고
    • The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle
    • Muhlhausler BS, Duffield JA, Ozanne SE, Pilgrim C, Turner N, et al. (2009) The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle. The Journal of Physiology 587: 4199-4211.
    • (2009) The Journal of Physiology , vol.587 , pp. 4199-4211
    • Muhlhausler, B.S.1    Duffield, J.A.2    Ozanne, S.E.3    Pilgrim, C.4    Turner, N.5
  • 47
    • 84860341404 scopus 로고    scopus 로고
    • Placental restriction reduces insulin sensitivity and expression of insulin signaling and glucose transporter genes in skeletal muscle, but not liver, in young sheep
    • De Blasio MJ, Gatford KL, Harland ML, Robinson JS, Owens JA, (2012) Placental restriction reduces insulin sensitivity and expression of insulin signaling and glucose transporter genes in skeletal muscle, but not liver, in young sheep. Endocrinology 153: 2142-2151.
    • (2012) Endocrinology , vol.153 , pp. 2142-2151
    • De Blasio, M.J.1    Gatford, K.L.2    Harland, M.L.3    Robinson, J.S.4    Owens, J.A.5
  • 48
    • 76749120289 scopus 로고    scopus 로고
    • Restriction of placental and fetal growth reduces expression of insulin signalling and glucose transporter genes in skeletal muscle of young lambs
    • Owens JA, Harland ML, De Blasio MJ, Gatford KL, Robinson JS, (2007) Restriction of placental and fetal growth reduces expression of insulin signalling and glucose transporter genes in skeletal muscle of young lambs. Early Human Development 83: S134 (abstract).
    • (2007) Early Human Development , vol.83
    • Owens, J.A.1    Harland, M.L.2    De Blasio, M.J.3    Gatford, K.L.4    Robinson, J.S.5
  • 49
    • 0037341252 scopus 로고    scopus 로고
    • Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat
    • Stoffers DA, Desai BM, De Leon DD, Simmons RA, (2003) Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat. Diabetes 52: 734-740.
    • (2003) Diabetes , vol.52 , pp. 734-740
    • Stoffers, D.A.1    Desai, B.M.2    De Leon, D.D.3    Simmons, R.A.4
  • 51
    • 79959803070 scopus 로고    scopus 로고
    • Incretin effects on β-cell function, replication, and mass: the human perspective
    • Garber AJ, (2011) Incretin effects on β-cell function, replication, and mass: the human perspective. Diabetes Care pp. S258+.
    • (2011) Diabetes Care
    • Garber, A.J.1
  • 52
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, Zhang B, Mac SM, et al. (2006) Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes. Diabetes Obesity Metab 8: 436-447.
    • (2006) Diabetes Obesity Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3    Zhang, B.4    Mac, S.M.5
  • 53
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, Kim DD, Fineman MS, et al. (2004) Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 27: 2628-2635.
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5
  • 54
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • DeFronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, et al. (2005) Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 28: 1092-1100.
    • (2005) Diabetes Care , vol.28 , pp. 1092-1100
    • DeFronzo, R.A.1    Ratner, R.E.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5
  • 55
    • 0036381989 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
    • Wang QW, Brubaker PLB, (2002) Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice. Diabetologia 45: 1263-1273.
    • (2002) Diabetologia , vol.45 , pp. 1263-1273
    • Wang, Q.W.1    Brubaker, P.L.B.2
  • 56
    • 33644803761 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
    • Ding X, Saxena NK, Lin S, Gupta N, Anania FA, (2006) Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology 43: 173-181.
    • (2006) Hepatology , vol.43 , pp. 173-181
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Gupta, N.4    Anania, F.A.5
  • 57
    • 0038497464 scopus 로고    scopus 로고
    • Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
    • Kolterman OG, Buse JB, Fineman MS, Gaines E, Heintz S, et al. (2003) Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 88: 3082-3089.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3082-3089
    • Kolterman, O.G.1    Buse, J.B.2    Fineman, M.S.3    Gaines, E.4    Heintz, S.5
  • 58
    • 0027391607 scopus 로고
    • Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
    • Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, et al. (1993) Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 91: 301-307.
    • (1993) J Clin Invest , vol.91 , pp. 301-307
    • Nauck, M.A.1    Heimesaat, M.M.2    Orskov, C.3    Holst, J.J.4    Ebert, R.5
  • 59
    • 27744541052 scopus 로고    scopus 로고
    • Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
    • Fehse F, Trautmann M, Holst JJ, Halseth AE, Nanayakkara N, et al. (2005) Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 90: 5991-5997.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5991-5997
    • Fehse, F.1    Trautmann, M.2    Holst, J.J.3    Halseth, A.E.4    Nanayakkara, N.5
  • 60
    • 74849108033 scopus 로고    scopus 로고
    • Exendin-4 potentiates insulinotropic action partly via increasing β-cell proliferation and neogenesis and decreasing apoptosis in association with the attenuation of endoplasmic reticulum stress in islets of diabetic rats
    • Kwon DY, Kim YS, Ahn IS, Kim DS, Kang S, et al. (2009) Exendin-4 potentiates insulinotropic action partly via increasing β-cell proliferation and neogenesis and decreasing apoptosis in association with the attenuation of endoplasmic reticulum stress in islets of diabetic rats. J Pharmacol Sci 111: 361-371.
    • (2009) J Pharmacol Sci , vol.111 , pp. 361-371
    • Kwon, D.Y.1    Kim, Y.S.2    Ahn, I.S.3    Kim, D.S.4    Kang, S.5
  • 61
    • 0021088185 scopus 로고
    • Enhanced synthesis, storage, and secretion of insulin in pancreatic islets derived from obese subjects
    • Jahr H, Ratzmann KP, Beckert R, Besch W, Hahn HJ, (1983) Enhanced synthesis, storage, and secretion of insulin in pancreatic islets derived from obese subjects. Metabolism 32: 1101-1106.
    • (1983) Metabolism , vol.32 , pp. 1101-1106
    • Jahr, H.1    Ratzmann, K.P.2    Beckert, R.3    Besch, W.4    Hahn, H.J.5
  • 62
    • 0025182175 scopus 로고
    • Beta-cell hyperresponsiveness: earliest event in development of diabetes in monkeys
    • Hansen BC, Bodkin NL, (1990) Beta-cell hyperresponsiveness: earliest event in development of diabetes in monkeys. Am J Physiol Regul Integr Comp Physiol 259: R612-R617.
    • (1990) Am J Physiol Regul Integr Comp Physiol , vol.259
    • Hansen, B.C.1    Bodkin, N.L.2
  • 63
    • 23644433355 scopus 로고    scopus 로고
    • Mechanisms of compensatory β-cell growth in insulin-resistant rats
    • Jetton TL, Lausier J, LaRock K, Trotman WE, Larmie B, et al. (2005) Mechanisms of compensatory β-cell growth in insulin-resistant rats. Diabetes 54: 2294-2304.
    • (2005) Diabetes , vol.54 , pp. 2294-2304
    • Jetton, T.L.1    Lausier, J.2    LaRock, K.3    Trotman, W.E.4    Larmie, B.5
  • 64
    • 84856242456 scopus 로고    scopus 로고
    • Exenatide as a weight-loss therapy in extreme pediatric obesity: A randomized, controlled pilot study
    • Kelly AS, Metzig AM, Rudser KD, Fitch AK, Fox CK, et al. (2012) Exenatide as a weight-loss therapy in extreme pediatric obesity: A randomized, controlled pilot study. Obesity 20: 364-370.
    • (2012) Obesity , vol.20 , pp. 364-370
    • Kelly, A.S.1    Metzig, A.M.2    Rudser, K.D.3    Fitch, A.K.4    Fox, C.K.5
  • 65
    • 0037045845 scopus 로고    scopus 로고
    • Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study
    • Zander M, Madsbad S, Madsen JL, Holst JJ, (2002) Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study. Lancet 359: 824-830.
    • (2002) Lancet , vol.359 , pp. 824-830
    • Zander, M.1    Madsbad, S.2    Madsen, J.L.3    Holst, J.J.4
  • 66
    • 15444380712 scopus 로고    scopus 로고
    • Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight
    • Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, et al. (2005) Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight. Endocrinology 146: 2069-2076.
    • (2005) Endocrinology , vol.146 , pp. 2069-2076
    • Gedulin, B.R.1    Nikoulina, S.E.2    Smith, P.A.3    Gedulin, G.4    Nielsen, L.L.5
  • 67
    • 52449129375 scopus 로고    scopus 로고
    • Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels
    • Li L, Yang G, Li Q, Tan X, Liu H, et al. (2008) Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels. Diabetes Obesity Metab 10: 921-930.
    • (2008) Diabetes Obesity Metab , vol.10 , pp. 921-930
    • Li, L.1    Yang, G.2    Li, Q.3    Tan, X.4    Liu, H.5
  • 68
    • 70449699592 scopus 로고    scopus 로고
    • Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents
    • Arakawa M, Ebato C, Mita T, Hirose T, Kawamori R, et al. (2009) Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. Biochem Biophys Res Comm 390: 809-814.
    • (2009) Biochem Biophys Res Comm , vol.390 , pp. 809-814
    • Arakawa, M.1    Ebato, C.2    Mita, T.3    Hirose, T.4    Kawamori, R.5
  • 70
    • 55549136417 scopus 로고    scopus 로고
    • Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study
    • DeFronzo RA, Okerson T, Viswanathan P, Guan X, Holcombe JH, et al. (2008) Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr Med Res Opin 24: 2943-2952.
    • (2008) Curr Med Res Opin , vol.24 , pp. 2943-2952
    • DeFronzo, R.A.1    Okerson, T.2    Viswanathan, P.3    Guan, X.4    Holcombe, J.H.5
  • 71
    • 56549107405 scopus 로고    scopus 로고
    • Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes
    • DOI:10.1016/j.regpep.2008.07.003
    • Linnebjerg H, Park S, Kothare PA, Trautmann ME, Mace K, et al. (2008) Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes. Regulatory Peptides DOI:10.1016/j.regpep.2008.07.003.
    • (2008) Regulatory Peptides
    • Linnebjerg, H.1    Park, S.2    Kothare, P.A.3    Trautmann, M.E.4    Mace, K.5
  • 72
    • 0033194372 scopus 로고    scopus 로고
    • Effects of feed restriction and cold exposure on glucose metabolism in response to feeding and insulin in sheep
    • Sano H, Takebayashi A, Kodama Y, Nakamura K, Ito H, et al. (1999) Effects of feed restriction and cold exposure on glucose metabolism in response to feeding and insulin in sheep. J Anim Sci 77: 2564-2573.
    • (1999) J Anim Sci , vol.77 , pp. 2564-2573
    • Sano, H.1    Takebayashi, A.2    Kodama, Y.3    Nakamura, K.4    Ito, H.5
  • 73
    • 0032807653 scopus 로고    scopus 로고
    • Suboptimal energy balance selectively up-regulates muscle GLUT gene expression but reduces insulin-dependent glucose uptake during postnatal development
    • Katsumata M, Burton KA, Li J, Dauncey MJ, (1999) Suboptimal energy balance selectively up-regulates muscle GLUT gene expression but reduces insulin-dependent glucose uptake during postnatal development. FASEB J 13: 1405-1413.
    • (1999) FASEB J , vol.13 , pp. 1405-1413
    • Katsumata, M.1    Burton, K.A.2    Li, J.3    Dauncey, M.J.4
  • 74
    • 0037349072 scopus 로고    scopus 로고
    • Entry of exendin-4 into brain is rapid but may be limited at high doses
    • Kastin AJ, Akerstrom V, (2003) Entry of exendin-4 into brain is rapid but may be limited at high doses. Int J Obesity Rel Metab Disorders 27: 313.
    • (2003) Int J Obesity Rel Metab Disorders , vol.27 , pp. 313
    • Kastin, A.J.1    Akerstrom, V.2
  • 75
    • 74849108033 scopus 로고    scopus 로고
    • Exendin-4 potentiates insulinotropic action partly via increasing β-cell proliferation and neogenesis and decreasing apoptosis in association with the attenuation of endoplasmic reticulum stress in islets of diabetic rats
    • Kwon DY, Kim YS, Ahn IS, Kim DS, Kang S, et al. (2009) Exendin-4 potentiates insulinotropic action partly via increasing β-cell proliferation and neogenesis and decreasing apoptosis in association with the attenuation of endoplasmic reticulum stress in islets of diabetic rats. Journal of Pharmacological Sciences 111: 361-371.
    • (2009) Journal of Pharmacological Sciences , vol.111 , pp. 361-371
    • Kwon, D.Y.1    Kim, Y.S.2    Ahn, I.S.3    Kim, D.S.4    Kang, S.5
  • 76
    • 27744541052 scopus 로고    scopus 로고
    • Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
    • Fehse F, Trautmann M, Holst JJ, Halseth AE, Nanayakkara N, et al. (2005) Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism 90: 5991-5997.
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , pp. 5991-5997
    • Fehse, F.1    Trautmann, M.2    Holst, J.J.3    Halseth, A.E.4    Nanayakkara, N.5
  • 77
    • 0032908654 scopus 로고    scopus 로고
    • Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)
    • Young AA, Gedulin BR, Bhavsar S, Bodkin N, Jodka C, et al. (1999) Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta). Diabetes 48: 1026-1034.
    • (1999) Diabetes , vol.48 , pp. 1026-1034
    • Young, A.A.1    Gedulin, B.R.2    Bhavsar, S.3    Bodkin, N.4    Jodka, C.5
  • 78
    • 15444380712 scopus 로고    scopus 로고
    • Exenatide (Exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight
    • Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, et al. (2005) Exenatide (Exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight. Endocrinology 146: 2069-2076.
    • (2005) Endocrinology , vol.146 , pp. 2069-2076
    • Gedulin, B.R.1    Nikoulina, S.E.2    Smith, P.A.3    Gedulin, G.4    Nielsen, L.L.5
  • 80
    • 0032191009 scopus 로고    scopus 로고
    • Insulin resistance in obesity: Metabolic mechanisms and measurement methods
    • Belfiore F, Iannello S, (1998) Insulin resistance in obesity: Metabolic mechanisms and measurement methods. Mol Genetics Metab 65: 121-128.
    • (1998) Mol Genetics Metab , vol.65 , pp. 121-128
    • Belfiore, F.1    Iannello, S.2
  • 81
    • 70349634594 scopus 로고    scopus 로고
    • Adipose tissue plasticity during catch-up fat driven by thrifty metabolism
    • Summermatter S, Marcelino H, Arsenijevic D, Buchala A, Aprikian O, et al. (2009) Adipose tissue plasticity during catch-up fat driven by thrifty metabolism. Diabetes 58: 2228-2237.
    • (2009) Diabetes , vol.58 , pp. 2228-2237
    • Summermatter, S.1    Marcelino, H.2    Arsenijevic, D.3    Buchala, A.4    Aprikian, O.5
  • 83
    • 0034620969 scopus 로고    scopus 로고
    • Association between postnatal catch-up growth and obesity in childhood: prospective cohort study
    • Ong KKL, Ahmed ML, Emmett PM, Preece MA, Dunger DB, (2000) Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. BMJ 320: 967-971.
    • (2000) BMJ , vol.320 , pp. 967-971
    • Ong, K.K.L.1    Ahmed, M.L.2    Emmett, P.M.3    Preece, M.A.4    Dunger, D.B.5
  • 85
    • 33846781645 scopus 로고    scopus 로고
    • Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity and adiposity in the young lamb
    • De Blasio MJ, Gatford KL, Robinson JS, Owens JA, (2007) Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity and adiposity in the young lamb. American Journal of Physiology 292: R875-R886.
    • (2007) American Journal of Physiology , vol.292
    • De Blasio, M.J.1    Gatford, K.L.2    Robinson, J.S.3    Owens, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.