LC/MS/MS evaluation of cocaine and its metabolites in different brain areas, peripheral organs and plasma in cocaine self-administering rats

Pharmacological Reports

Volumn 64, Issue 6, 2012, Pages 1337-1349

  Bystrowska, Beata ^a   Adamczyk, Przemysław ^b   Moniczewski, Andrzej ^a   Zaniewska, Magdalena ^b   Fuxe, Kjell ^c   Filip, Małgorzata ^a,b  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Benzoylecgonine; Brain structures; Cocaine; Kinetic; LC MS MS; Metabolism; Norcocaine

Indexed keywords

BENZOYLECGONINE; COCAINE; DRUG METABOLITE; NORCOCAINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD LEVEL; BRAIN LEVEL; CEREBELLUM; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; COCAINE DEPENDENCE; CORPUS STRIATUM; FRONTAL CORTEX; HALF LIFE TIME; HEART; HIPPOCAMPUS; KIDNEY; KIDNEY CLEARANCE; LIQUID CHROMATOGRAPHY; LIVER; LIVER CLEARANCE; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; RAT; REINFORCEMENT; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION STUDY; WITHDRAWAL SYNDROME;

EID: 84873701859     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/s1734-1140(12)70931-3     Document Type: Article

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