Additive value of blood neutrophil gelatinase-associated lipocalin to clinical judgement in acute kidney injury diagnosis and mortality prediction in patients hospitalized from the emergency department

Critical Care

Volumn 17, Issue 1, 2013, Pages

  Di Somma, Salvatore ^a   Magrini, Laura ^a   De Berardinis, Benedetta ^a   Marino, Rossella ^a   Ferri, Enrico ^a   Moscatelli, Paolo ^b   Ballarino, Paola ^b   Carpinteri, Giuseppe ^c   Noto, Paola ^c   Gliozzo, Biancamaria ^c   Paladino, Lorenzo ^d   Di Stasio, Enrico ^e  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF CATANIA   (Italy)

^d KINGS COUNTY HOSPITAL CENTER   (United States)

^e CATHOLIC UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CLINICAL DECISION MAKING; COHORT ANALYSIS; CREATININE BLOOD LEVEL; DIAGNOSTIC VALUE; DISEASE CLASSIFICATION; EMERGENCY WARD; FEMALE; GLOMERULUS FILTRATION RATE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEPHROLOGIST; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

EID: 84873700129     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc12510     Document Type: Article

References (45)

1. Xue J, Daniels F, Star RA, Kimmel PL, Eggers PW, Molitoris BA, Himmelfarb J, Collins AJ. Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001. JASN 2006, 17:1135-1142. 10.1681/ASN.2005060668, 16495381.
2. Coca SG, Yusuf B, Shlipak MG, Garg AX, Parikh CR. Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 2009, 53:961-973. 10.1053/j.ajkd.2008.11.034, 2726041, 19346042.
3. Joslin J, Ostermann M. Care of the critically ill emergency department patient with acute kidney injury. Emerg Med Int 2012, 760623.
4. Nickolas TL, Schmidt-Ott KM, Canetta P, Forster C, Singer E, Sise M, Elger A, Maarouf O, Sola-Del Valle DA, O'Rourke M, Sherman E, Lee P, Geara A, Imus P, Guddati A, Polland A, Rahman W, Elitok S, Malik N, Giglio J, El-Sayegh S, Devarajan P, Hebbar S, Saggi SJ, Hahn B, Kettritz R, Luft FC, Barasch J. Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage a multicenter prospective cohort study. J Am Coll Cardiol 2012, 59:246-255. 10.1016/j.jacc.2011.10.854, 3487165, 22240130.
5. Nickolas TL, O'Rourke MJ, Yang J, Sise ME, Canetta PA, Barasch N, Buchen C, Khan F, Mori K, Giglio J, Devarajan P, Barasch J. Sensitivity and specificity of a single Emergency Department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Inter Med 2008, 148:810-819.
6. Ostermann M, Chang R. Correlation between the AKI classification and outcome. Crit Care 2008, 12:R144. 10.1186/cc7123, 2646305, 19019254.
7. Chuasuwan A, Kellum JA. Acute kidney injury and its management. Contrib Nephrol 2011, 171:218-225.
8. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure, definition, outcome measures, animal models fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004, 8:R204-212. 10.1186/cc2872, 522841, 15312219.
9. Metha RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007, 11:R31. 10.1186/cc5713, 2206446, 17331245.
10. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2012, 2:1-138. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group.
11. Urbschat A, Obermüller N, Haferkamp A. Biomarkers of kidney injury. Biomarkers 2011, Suppl 1:22-30.
12. Ronco C, Kellum JA, Haase M. Subclinical AKI is still AKI. Crit Care 2012, 16:313. 10.1186/cc10920, 22721504.
13. Haase M, Devarajan P, Haase-Fielitz A, Bellomo R, Cruz DN, Wagener G, Krawczeski CD, Koyner JL, Murray P, Zappitelli M, Goldstein SL, Makris K, Ronco C, Martensson J, Martling CR, Venge P, Siew E, Ware LB, Ikizler TA, Mertens PR. The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury. J Am Coll Cardiol 2011, 57:1752-1761. 10.1016/j.jacc.2010.11.051, 21511111.
14. Shemin D, Dworkin LD. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for early acute kidney injury. Crit Care Clin 2011, 27:379-389. 10.1016/j.ccc.2010.12.003, 21440207.
15. Haase M, Haase-Fielitz A. NGAL-From discovery to a new era of "Acute Renal Disease" diagnosis?. Clin Biochem 2011, 44:499-500. 10.1016/j.clinbiochem.2011.02.023, 22036346.
16. Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J. Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol 2007, 18:407-413. 10.1681/ASN.2006080882, 17229907.
17. Haase M, Bellomo R, Devarajan P, Schlattmann P, Haase-Fielitz A. NGAL Meta-analysis Investigator Group. Am J Kidney Dis 2009, 54:1012-1024. 10.1053/j.ajkd.2009.07.020, 19850388.
18. Dent CL, Ma Q, Dastrala S, Bennett M, Mitsnefes MM, Barasch J, Devarajan P. Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care 2007, 11:R127. 10.1186/cc6192, 2246223, 18070344.
19. Doi K, Negishi K, Ishizu T, Katagiri D, Fujita T, Matsubara T, Yahagi N, Sugaya T, Noiri E. Evaluation of new acute kidney injury biomarkers in a mixed intensive care unit. Crit Care Med 2011, 39:2464-2469. 10.1097/CCM.0b013e318225761a, 21705884.
20. Cruz DN, de Cal M, Garzotto F, Perazella MA, Lentini P, Corradi V, Piccinni P, Ronco C. Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population. Intensive Care Med 2010, 36:444-451. 10.1007/s00134-009-1711-1, 2820221, 19956925.
21. de Geus HRH, Bakker J, Lesaffre EMEH, leNoble JLML. Neutrophil gelatinase-associated lipocalin at ICU admission predict for acute kidney injury in adult patients. Am J Resp Crit Care Med 2011, 183:907-914. 10.1164/rccm.200908-1214OC, 20935115.
22. Shapiro NI, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson K, Milzman D, Gaieski DF, Goyal M, Cairns CB, Kupfer K, Lee SW, Rivers EP. The diagnostic accuracy of plasma neutrophil gelatinase-associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis. Ann Emerg Med 2010, 56:52-59. 10.1016/j.annemergmed.2010.02.010, 20363526.
23. Oussana MNK. Guidelines for the prevention management and care of diabetes mellitus. World Health Organization 2006,
24. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Struijker Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina1 R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, et al. Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007, 28:1462-1536.
25. McCord J, Nowak RM, Jacobsen G, Sallach JA, Wu AH, Perez A, Omland T, Knudsen CW, Westheim A, Duc P, Steg PG, Hollander JE, Herrmann HC, Storrow AB, Abraham WT, Lamba S, McCullough PA, Maisel A. B-type natriuretic peptide and clinical judgment in emergency diagnosis of heart failure: analysis from Breathing Not Properly (BNP) Multinational Study. Circulation 2002, 106:416-422. 10.1161/01.CIR.0000025242.79963.4C, 12135939.
26. Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 2005, 365:1231-1238. 10.1016/S0140-6736(05)74811-X, 15811456.
27. Levey AS, Stevens LA, Schmid CH, , et al. for the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) A new equation to estimate glomerular filtration rate. Ann Intern Med 2009, 150:604-612. 2763564, 19414839, for the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration).
28. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976, 16:31-41. 10.1159/000180580, 1244564.
29. Endre ZH. Renal ischemic preconditioning: finally some good news for prevention of acute kidney injury. Kidney Int 2011, 80:796-798. 10.1038/ki.2011.193, 21960167.
30. Siew ED, Ware LB, Gebretsadik T, Shintani A, Moons KG, Wickersham N, Bossert F, Ikizler TA. Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol 2009, 20:1823-1832. 10.1681/ASN.2008070673, 2723988, 19628673.
31. Kümpers P, Hafer C, Lukasz A, Lichtinghagen R, Brand K, Fliser D, Faulhaber-Walter R, Kielstein JT. Serum neutrophil gelatinase-associated lipocalin at inception of renal replacement therapy predicts survival in critically ill patients with acute kidney injury. Crit Care 2010, 14:R9. 10.1186/cc8861, 2875521, 20122150.
32. Srisawat N, Murugan R, Lee M, Kong L, Carter M, Angus DC, Kellum JA, Genetic and Inflammatory Markers of Sepsis (GenIMS) Study Investigators Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int 2011, 80:545-552. 10.1038/ki.2011.160, 3257035, 21677634, Genetic and Inflammatory Markers of Sepsis (GenIMS) Study Investigators.
33. Haase M, Haase-Fielitz A. Can novel biomarkers complement best possible clinical assessment for early acute kidney injury diagnosis?. J Am Coll Cardiol 2011, 58:2310-2312. 10.1016/j.jacc.2011.08.014, 22093508.
34. James MT, Tonelli M, Alberta Kidney Disease Network Financial aspects of renal replacement therapy in acute kidney injury. emin Dial 2011, 24:215-219. Alberta Kidney Disease Network.
35. Breidthardt T, Christ-Crain M, Stolz D, Bingisser R, Drexler B, Klima T, Balmelli C, Schuetz P, Haaf P, Schärer M, Tamm M, Müller B, Müller C. A combined cardiorenal assessment by the prediction of acute kidney injury in lower respiratory tract infections. Am J Med 2012, 125:168-175. 10.1016/j.amjmed.2011.07.010, 22269620.
36. Maisel AS, Mueller C, Fitzgerald R, Brikhan R, Hiestand BC, Iqbal N, Clopton P, van Veldhuisen DJ. Prognostic utility of plasma neutrophil gelatinase-associated lipocalin in patients with acute heart failure: the NGAL EvaLuation Along with B-type NaTriuretic Peptide in acutely decompensated heart failure (GALLANT) trial. Eur J Heart Fail 2011, 13:846-851. 10.1093/eurjhf/hfr087, 3143832, 21791540.
37. Bennett M, Dent CL, Ma Q, Dastrala S, Grenier F, Workman R, Syed H, Ali S, Barasch J, Devarajan P. Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol 2008, 3:665-673. 10.2215/CJN.04010907, 2386703, 18337554.
38. Singer E, Elger A, Elitok S, Kettritz R, Nickolas TL, Barasch J, Luft FC, Schmidt-Ott KM. Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes. Kidney Int 2011, 80:405-414. 10.1038/ki.2011.41, 21412214.
39. Mårtensson J, Bell M, Oldner A, Xu S, Venge P, Martling CR. Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury. Intensive Care Med 2010, 36:1333-1340. 10.1007/s00134-010-1887-4, 20397003.
40. Doi K, Noiri E, Maeda-Mamiya R, Ishii T, Negishi K, Hamasaki Y, Fujita T, Yahagi N, Koide H, Sugaya T, Nakamura T. Urinary L-type fatty acid-binding protein as a new biomarker of sepsis complicated with acute kidney injury. Crit Care Med 2010, 38:2037-2042.
41. Bagshaw SM, Bennett M, Haase M, Haase-Fielitz A, Egi M, Morimatsu H, D'amico G, Goldsmith D, Devarajan P, Bellomo R. Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness. Intensive Care Med 2010, 36:452-461. 10.1007/s00134-009-1724-9, 19956924.
42. Di Somma S, Gori CS, Salvatori E. How to manage cardiorenal syndromes in the emergency room. Contrib Nephrol 2010, 165:93-100.
43. Alvelos M, Pimentel R, Pinho E, Gomes A, Lourenço P, Teles MJ, Almeida P, Guimarães JT, Bettencourt P. Neutrophil gelatinase-associated lipocalin in the diagnosis of type 1 cardio-renal syndrome in the general ward. Clin J Am Soc Nephrol 2011, 6:476-481. 10.2215/CJN.06140710, 3082403, 21115620.
44. Hawkins R. New biomarkers of acute kidney injury and the cardio-renal syndrome. Korean J Lab Med 2011, 31:72-80. 10.3343/kjlm.2011.31.2.72, 3116003, 21474979.
45. Maisel A, Mueller C, Adams K, Anker SD, Aspromonte N, Cleland JG, Cohen-Solal A, Dahlstrom U, DeMaria A, DiSomma S, Filippatos GS, Fonarow GC, Jourdain P, Komajda M, Liu PP, McDonagh T, McDonald K, Mebazaa A, Nieminen MS, Peacock WF, Tubaro M, Valle R, Vanderhyden M, Yancy CW, Zannad F, Braunwald E. State of the art: using natriuretic peptide levels in clinical practice. Eur J Heart Fail 2008, 10:824-839. 10.1016/j.ejheart.2008.07.014, 18760965.