Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis

Journal of Infectious Diseases

Volumn 207, Issue 5, 2013, Pages 778-785

  Pinto, Rachel ^a,b   Leotta, Lisa ^a,b   Shanahan, Erin R ^a   West, Nicholas P ^a   Leyh, Thomas S ^c   Britton, Warwick ^a,b   Triccas, James A ^a,b  

^a Centenary Institute   (United States)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

ATP sulfurylase; human immune response; sulfate metabolism; tuberculosis; vaccine

Indexed keywords

ADENOSINE 5' TRIPHOSPHATE SULFURYLASE DNA VACCINE; BCG VACCINE; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; DNA VACCINE; GUANOSINE TRIPHOSPHATASE PLUS ADENYLYLSULFATE KINASE DNA VACCINE; MESSENGER RNA; PHOSPHORYL LIPID A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL LOAD; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL VIRULENCE; BCG VACCINATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; FEMALE; HOST CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; SULFATE ASSIMILATION PATHWAY; T LYMPHOCYTE;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; SULFATES; T-LYMPHOCYTES; TUBERCULOSIS; TUBERCULOSIS VACCINES; UP-REGULATION; VACCINES, SUBUNIT;

EID: 84873679251     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis751     Document Type: Article

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