-
1
-
-
39449085063
-
DNA damage repair; The good, the bad, and the ugly
-
Hakem R: DNA damage repair; the good, the bad, and the ugly. EMBO J 27: 589-605, 2008.
-
(2008)
EMBO J
, vol.27
, pp. 589-605
-
-
Hakem, R.1
-
2
-
-
33344476097
-
DNA damage checkpoints in mammals
-
Niida H and Nakanishi M: DNA damage checkpoints in mammals. Mutagenesis 21: 3-9, 2006.
-
(2006)
Mutagenesis
, vol.21
, pp. 3-9
-
-
Niida, H.1
Nakanishi, M.2
-
3
-
-
34249780384
-
Lessons learned from DNA repair defective syndromes
-
Thoms KM, Kuschal C and Emmert S: Lessons learned from DNA repair defective syndromes. Exp Dermatol 16: 532-544, 2007.
-
(2007)
Exp Dermatol
, vol.16
, pp. 532-544
-
-
Thoms, K.M.1
Kuschal, C.2
Emmert, S.3
-
4
-
-
33749037701
-
Mechanism of homologous recombination: Mediators and helicases take on regulatory functions
-
Sung P and Klein H: Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nature Rev Mol Cell Biol 7: 739-750, 2006.
-
(2006)
Nature Rev Mol Cell Biol
, vol.7
, pp. 739-750
-
-
Sung, P.1
Klein, H.2
-
5
-
-
0037086702
-
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
-
Kang J, Bronson RT and Xu Y: Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J 21: 1447-1455, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 1447-1455
-
-
Kang, J.1
Bronson, R.T.2
Xu, Y.3
-
6
-
-
0242610857
-
Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation induced tumorigenesis
-
Dumon-Jones V, Frappart PO, Tong WM, et al: Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation induced tumorigenesis. Cancer Res 63: 7263-7269, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 7263-7269
-
-
Dumon-Jones, V.1
Frappart, P.O.2
Tong, W.M.3
-
7
-
-
18844394291
-
An essential function for NBS1 in the prevention of ataxia and cerebellar defects
-
Frappart PO, Tong WM, Demuth I, et al: An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nat Med 11: 538-544, 2005.
-
(2005)
Nat Med
, vol.11
, pp. 538-544
-
-
Frappart, P.O.1
Tong, W.M.2
Demuth, I.3
-
8
-
-
56649086648
-
Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer predisposing gene
-
Bartkova J, Tommiska J, Oplustilova L, et al: Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer predisposing gene. Mol Oncol 2: 296-316, 2008.
-
(2008)
Mol Oncol
, vol.2
, pp. 296-316
-
-
Bartkova, J.1
Tommiska, J.2
Oplustilova, L.3
-
9
-
-
38349052915
-
Nijmegen breakage syndrome mutations and risk of breast cancer
-
Bogdanova N, Feschchenko S, Schurmann P, et al: Nijmegen breakage syndrome mutations and risk of breast cancer. Int J Cancer 122: 802-806, 2008.
-
(2008)
Int J Cancer
, vol.122
, pp. 802-806
-
-
Bogdanova, N.1
Feschchenko, S.2
Schurmann, P.3
-
10
-
-
33750476354
-
Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women less than or equal to 55 years
-
Lu J, Wei Q, Bondy ML, et al: Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women less than or equal to 55 years. Carcinogenesis 27: 2209-2216, 2006.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2209-2216
-
-
Lu, J.1
Wei, Q.2
Bondy, M.L.3
-
11
-
-
35448952908
-
Breast cancer risk is associated with the genes encoding the DNA double strand break repair Mre11/Rad50/Nbs1 complex
-
Hsu HM, Wang HC, Chen ST, Hsu GC, Shen CY and Yu JC: Breast cancer risk is associated with the genes encoding the DNA double strand break repair Mre11/Rad50/Nbs1 complex. Cancer Epidemiol Biomarkers Prev 16: 2024-2032, 2007.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 2024-2032
-
-
Hsu, H.M.1
Wang, H.C.2
Chen, S.T.3
Hsu, G.C.4
Shen, C.Y.5
Yu, J.C.6
-
12
-
-
34247095553
-
Intact Mre11/Rad50/Nbs1 complex predicts good response to radiotherapy in early breast cancer
-
Soderlund K, Stal O, Skoog L, Rutqvist LE, Nordenskjold B and Askmalm MS: Intact Mre11/Rad50/Nbs1 complex predicts good response to radiotherapy in early breast cancer. Int J Rad Oncol Biol Physics 68: 50-58, 2007.
-
(2007)
Int J Rad Oncol Biol Physics
, vol.68
, pp. 50-58
-
-
Soderlund, K.1
Stal, O.2
Skoog, L.3
Rutqvist, L.E.4
Nordenskjold, B.5
Askmalm, M.S.6
-
13
-
-
33749171533
-
Association of ionizing radiation induced foci of NBS1 with chromosomal instability and breast cancer susceptibility
-
Someya M, Sakata K, Tauchi H, Matsumoto Y, Nakamura A, Komatsu K and Hareyama M: Association of ionizing radiation induced foci of NBS1 with chromosomal instability and breast cancer susceptibility. Rad Res 166: 575-582, 2006.
-
(2006)
Rad Res
, vol.166
, pp. 575-582
-
-
Someya, M.1
Sakata, K.2
Tauchi, H.3
Matsumoto, Y.4
Nakamura, A.5
Komatsu, K.6
Hareyama, M.7
-
14
-
-
0031597895
-
Role of hormones in cancer initiation and progression
-
Russo IH and Russo J: Role of hormones in cancer initiation and progression. J Mammary Gland Biol Neoplasia 3: 49-61, 1998.
-
(1998)
J Mammary Gland Biol Neoplasia
, vol.3
, pp. 49-61
-
-
Russo, I.H.1
Russo, J.2
-
15
-
-
0034234237
-
CBP/p300 in cell growth, transformation, and development
-
Goodman RH and Smolik S: CBP/p300 in cell growth, transformation, and development. Genes Dev 14: 1553-1577, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 1553-1577
-
-
Goodman, R.H.1
Smolik, S.2
-
16
-
-
33750487170
-
New role for nuclear hormone receptors and coactivators in regulation of BRCA1 mediated DNA repair in breast cancer cell lines
-
Crowe DL and Lee MK: New role for nuclear hormone receptors and coactivators in regulation of BRCA1 mediated DNA repair in breast cancer cell lines. Breast Cancer Res 8: 1-12, 2006.
-
(2006)
Breast Cancer Res
, vol.8
, pp. 1-12
-
-
Crowe, D.L.1
Lee, M.K.2
-
17
-
-
2942585693
-
A sensitive and rapid assay for homologous recombination in mosquito cells: Impact of vector topology and implications for gene targeting
-
Eggleston P and Zhao Y: A sensitive and rapid assay for homologous recombination in mosquito cells: impact of vector topology and implications for gene targeting. BMC Genet 2: 21-29, 2001.
-
(2001)
BMC Genet
, vol.2
, pp. 21-29
-
-
Eggleston, P.1
Zhao, Y.2
-
18
-
-
34248579748
-
The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex
-
Stracker TH, Morales M, Couto SS, Hussein H and Petrini JHJ: The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex. Nature 447: 218-222, 2007.
-
(2007)
Nature
, vol.447
, pp. 218-222
-
-
Stracker, T.H.1
Morales, M.2
Couto, S.S.3
Hussein, H.4
Petrini, J.H.J.5
-
19
-
-
33847280981
-
Estrogens decrease gamma ray induced senescence and maintain cell cycle progression in breast cancer cells independently of p53
-
Toillon RA, Magne N, Laios I, et al: Estrogens decrease gamma ray induced senescence and maintain cell cycle progression in breast cancer cells independently of p53. Int J Rad Oncol Biol Physics 67: 1187-1200, 2007.
-
(2007)
Int J Rad Oncol Biol Physics
, vol.67
, pp. 1187-1200
-
-
Toillon, R.A.1
Magne, N.2
Laios, I.3
-
20
-
-
0037805645
-
C-myc directly regulates the transcription of the NBS1 gene involved in DNA double strand break repair
-
Chiang YC, Teng SC, Su YN, Hsieh FJ and Wu KJ: c-myc directly regulates the transcription of the NBS1 gene involved in DNA double strand break repair. J Biol Chem 278: 19286 19291, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 19286-19291
-
-
Chiang, Y.C.1
Teng, S.C.2
Su, Y.N.3
Hsieh, F.J.4
Wu, K.J.5
-
21
-
-
64549154804
-
Functional four base A/T gap core sequence CATTAG of p53 response elements specifically bound tetrameric p53 differently than two base A/T gap core sequence CATG bound both dimeric and tetrameric p53
-
Cai BH, Chen JY, Lu MH, Chang LT, Lin HC, Chang YM and Chao CF: Functional four base A/T gap core sequence CATTAG of p53 response elements specifically bound tetrameric p53 differently than two base A/T gap core sequence CATG bound both dimeric and tetrameric p53. Nuc Acids Res 37: 1984-1990, 2009.
-
(2009)
Nuc Acids Res
, vol.37
, pp. 1984-1990
-
-
Cai, B.H.1
Chen, J.Y.2
Lu, M.H.3
Chang, L.T.4
Lin, H.C.5
Chang, Y.M.6
Chao, C.F.7
-
22
-
-
33744532403
-
Estrogen receptor alpha binds p53 tumor suppressor protein directly and represses its function
-
Liu W, Konduri SD, Bansai S, et al: Estrogen receptor alpha binds p53 tumor suppressor protein directly and represses its function. J Biol Chem 281: 9837-9840, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 9837-9840
-
-
Liu, W.1
Konduri, S.D.2
Bansai, S.3
-
23
-
-
0033305404
-
Steroid receptor coactivator 1 and its family members differentially regulate transactivation by the tumor suppressor protein p53
-
Lee SK, Kim HJ, Kim JW and Lee JW: Steroid receptor coactivator 1 and its family members differentially regulate transactivation by the tumor suppressor protein p53. Mol Endocrinol 13: 1924-1933, 1999.
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1924-1933
-
-
Lee, S.K.1
Kim, H.J.2
Kim, J.W.3
Lee, J.W.4
-
24
-
-
0035694469
-
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
-
Barlev NA, Liu L, Chehab NH, Mansfield K, Harris KG, Halazonetis TD and Berger SL: Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell 8: 1243-1254, 2001.
-
(2001)
Mol Cell
, vol.8
, pp. 1243-1254
-
-
Barlev, N.A.1
Liu, L.2
Chehab, N.H.3
Mansfield, K.4
Harris, K.G.5
Halazonetis, T.D.6
Berger, S.L.7
-
25
-
-
10744233648
-
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation
-
Mujtaba S, He Y, Zeng L, et al: Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Mol Cell 13: 251-263, 2004.
-
(2004)
Mol Cell
, vol.13
, pp. 251-263
-
-
Mujtaba, S.1
He, Y.2
Zeng, L.3
-
26
-
-
2442672704
-
The acetyltransferase p300/CBP associated factor is a p53 target gene in breast tumor cells
-
Watts GS, Oshiro MM, Junk DJ, Wozniak RJ, Watterson S, Domann FE and Futscher BW: The acetyltransferase p300/CBP associated factor is a p53 target gene in breast tumor cells. Neoplasia 6: 187-194, 2004.
-
(2004)
Neoplasia
, vol.6
, pp. 187-194
-
-
Watts, G.S.1
Oshiro, M.M.2
Junk, D.J.3
Wozniak, R.J.4
Watterson, S.5
Domann, F.E.6
Futscher, B.W.7
-
27
-
-
33846850422
-
Ten genes for inherited breast cancer
-
Walsh T and King MC: Ten genes for inherited breast cancer. Cancer Cell 11: 103-105, 2007.
-
(2007)
Cancer Cell
, vol.11
, pp. 103-105
-
-
Walsh, T.1
King, M.C.2
-
28
-
-
40449131773
-
Heterozygous carriers of the I171V mutation of the NBS1 gene have a significantly increased risk of solid malignant tumors
-
Nowak J, Mosor M, Ziolkowska I, et al: Heterozygous carriers of the I171V mutation of the NBS1 gene have a significantly increased risk of solid malignant tumors. Eur J Cancer 44: 627-630, 2008.
-
(2008)
Eur J Cancer
, vol.44
, pp. 627-630
-
-
Nowak, J.1
Mosor, M.2
Ziolkowska, I.3
-
29
-
-
11844259424
-
Functional interaction of H2AX, NBS1, and p53 in ATM dependent DNA damage responses and tumor suppression
-
Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW and Xu Y: Functional interaction of H2AX, NBS1, and p53 in ATM dependent DNA damage responses and tumor suppression. Mol Cell Biol 25: 661-670, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 661-670
-
-
Kang, J.1
Ferguson, D.2
Song, H.3
Bassing, C.4
Eckersdorff, M.5
Alt, F.W.6
Xu, Y.7
-
30
-
-
59449084112
-
Nuclear export of NBN is required for normal cellular responses to radiation
-
Vissinga CS, Yeo TC, Warren S, Brawley JV, Phillips J, Cerosaletti K and Concannon P: Nuclear export of NBN is required for normal cellular responses to radiation. Mol Cell Biol 29: 1000-1006, 2009.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1000-1006
-
-
Vissinga, C.S.1
Yeo, T.C.2
Warren, S.3
Brawley, J.V.4
Phillips, J.5
Cerosaletti, K.6
Concannon, P.7
-
31
-
-
62449332005
-
Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway
-
Shimada M, Sagae R, Kobayashi J, Habu T and Komatsu K: Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway. Cancer Res 69: 1768-1775, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 1768-1775
-
-
Shimada, M.1
Sagae, R.2
Kobayashi, J.3
Habu, T.4
Komatsu, K.5
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