Suppressive effects of Indigofera suffruticosa Mill extracts on lipopolysaccharide-induced inflammatory responses in murine RAW 264.7 macrophages

Food and Chemical Toxicology

Volumn 55, Issue , 2013, Pages 257-264

  Chen, Tzy Yen ^a,b   Sun, Hai Lun ^a,b   Yao, Hsien Tsung ^c   Lii, Chong Kuei ^c   Chen, Haw Wen ^c   Chen, Pei Yin ^b   Li, Chien Chun ^a,b   Liu, Kai Li ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Heme oxygenase 1; Indigofera suffruticosa; Inducible nitric oxide synthase; Inflammation; NF kB

Indexed keywords

ANTIINFLAMMATORY AGENT; DNA; FORMONONETIN; HEME OXYGENASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDIGOFERA SUFFRUTICOSA EXTRACT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; ISOLIQUIRITIGENIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PARA COUMARIC ACID; PHENOL DERIVATIVE; PLANT EXTRACT; QUERCETIN; SALICYLIC ACID; SYRINGALDEHYDE; SYRINGIC ACID; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANILLIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; DRUG POTENCY; IC 50; INDIGOFERA; INDIGOFERA SUFFRUTICOSA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SINGLE DRUG DOSE;

ANIMALS; BASE SEQUENCE; CELL LINE; INDIGOFERA; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; OLIGONUCLEOTIDES; PLANT EXTRACTS; SALICYLIC ACID;

EID: 84873670486     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.12.056     Document Type: Article

References (37)

1. Alam J., Stewart D., Touchard C., Boinapally S., Choi A.M., Cook J.L. Nrf2, a cap'n'collar transcription factor, regulates induction of the heme oxygenase-1 gene. J. Biol. Chem. 1999, 274:26071-26078.
2. Alam J., Cook J.L. How many transcription factors does it take to turn on the heme oxygenase-1 gene?. Am. J. Respir. Cell Mol. Biol. 2007, 36:166-174.
3. Chan K.H., Ng M.K., Stocker R. Haem oxygenase-1 and cardiovascular disease: mechanisms and therapeutic potential. Clin. Sci. 2011, 120:493-504.
4. Chen F., Castranova V., Shi X., Demers L.M. New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases. Clin. Chem. 1999, 45:7-17.
5. de A Carli C.B., Quilles M.B., Maia D.C., Lopes F.C., Santos R., Pavan F.R., Fujimura Leite C.Q., Calvo T.R., Vilegas W., Carlos I.Z. Antimycobacterial activity of Indigofera suffruticosa with activation potential of the innate immune system. Pharm. Biol. 2010, 48:878-882.
6. Denizot F., Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods 1986, 89:271-277.
7. Fürst R., Blumenthal S.B., Kiemer A.K., Zahler S., Vollmar A.M. Nuclear factor-kappa B-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the c-jun N-terminal kinase/activator protein-1 pathway. J. Pharmacol. Exp. Ther. 2006, 318:389-394.
8. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S., Tannenbaum S.R. Analysis of nitrate, nitrite, and [15N]-nitrate in biological fluids. Anal. Biochem. 1982, 126:131-138.
9. Hu C.M., Liu Y.H., Cheah K.P., Li J.S., Lam C.S., Yu W.Y., Choy C.S. Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide. J. Ethnopharmacol. 2009, 121:79-85.
10. Jazwa A., Cuadrado A. Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases. Curr. Drug Targets CNS Neurol. Disord. 2010, 11:517-531.
11. Jia Z., Tang M., Wu J. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 1999, 64:555-559.
12. King G.L. The role of inflammatory cytokines in diabetes and its complications. J. Periodontol. 2008, 79:1527-1534.
13. Kofler S., Nickel T., Weis M. Role of cytokines in cardiovascular diseases: a focus on endothelial responses to inflammation. Clinical Science 2005, 108:205-213.
14. Kundu J.K., Surh Y.J. Inflammation: gearing the journey to cancer. Mutat. Res. 2008, 659:15-30.
15. Lee C.J., Lee S.S., Chen S.C., Ho F.M., Lin W.W. Oregonin inhibits lipopolysaccharide-induced iNOS gene transcription and upregulates HO-1 expression in macrophages and microglia. Br. J. Pharmacol. 2005, 146:378-388.
16. Leite S.P., Silva L.L.S., Catanho M.T.J.A., Lima E.O., Lima V.L.M. Antiinflammatory activity of Indigofera suffruticosa extract. REBRASA 2003, 7:47-52.
17. Leite S.P., Vieira J.R., de Medeiros P.L., Leite R.M., de Menezes Lima V.L., Xavier H.S., de Oliveira Lima E. Antimicrobial activity of Indigofera suffruticosa. Evid. Complement. Alternat. Med. 2006, 3:261-265.
18. Liu K.L., Chen W.C., Wang R.Y., Lei Y.P., Sheen L.Y., Lii C.K. DATS reduces LPS-induced iNOS expression, NO production, oxidative stress and NF-B activation in RAW 264.7 macrophages. J. Agric. Food Chem. 2006, 54:3472-3478.
19. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] method. Methods 2001, 25:402-408.
20. Lopes F.C., Calvo T.R., Colombo L.L., Vilegas W., Carlos I.Z. Immunostimulatory and cytotoxic activities of Indigofera suffruticosa (Fabaceae). Nat. Prod. 2011, 25:1796-1806.
21. MacMicking J., Xie Q.W., Nathan C. Nitric oxide and macrophage function. Annu. Rev. Immunol. 1997, 15:323-350.
22. Maines M.D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 1988, 2:2557-2568.
23. Makarov S.S. NF-kappaB as a therapeutic target in chronic inflammation: recent advances. Mol. Med. Today 2000, 6:441-448.
24. Manzi S., Wasko M.C. Inflammation-mediated rheumatic diseases and atherosclerosis. Ann. Rheum. Dis. 2000, 59:321-325.
25. Moncada S., Palmer R.M.J., Higgs D.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 1992, 43:109-142.
26. National Research Council Guide for the Care and Use of Laboratory Animals, 1985. Publication No. 85-23 (revised). National Institutes of Health, Bethesda.
27. Nurmi K., Ossipov V., Haukioja E., Pihlaja K. Variation of total phenolic content and individual low-molecular-weight phenolics in foliage of mountain birch trees (Betula pubescens ssp. tortuosa). J. Chem. Ecol. 1996, 22:2023-2040.
28. Ryter S.W., Alam J., Choi A.M. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol. Rev. 2006, 86:583-650.
29. Seldon M.P., Silva G., Pejanovic N., Larsen R., Gregoire I.P., Filipe J., Anrather J., Soares M.P. Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276. J. Immunol. 2007, 179:7840-7851.
30. Stylianou E., Saklatvala J. Interleukin-1. Int. J. Biochem. Cell Biol. 1998, 30:1075-1079.
31. Tak P.P., Firestein G.S. NF-kappaB: a key role in inflammatory diseases. J. Clin. Invest. 2001, 107:7-11.
32. Tsuburai T., Kaneko T., Nagashima Y., Ueda A., Tagawa A., Shinohara T., Ishigatsubo Y. Pseudomonas aeruginosa-induced neutrophilic lung inflammation is attenuated by adenovirus-mediated transfer of the heme oxygenase 1 cDNA in mice. Hum. Gene Ther. 2004, 15:273-285.
33. Vieira J.R., de Souza I.A., do Nascimento S.C., Leite S.P. Indigofera suffruticosa: an alternative anticancer therapy. Evid. Complement. Alternat. Med. 2007, 4:355-359.
34. Wang W.W., Smith D.L., Zucker S.D. Bilirubin inhibits iNOS expression and NO production in response to endotoxin in rats. Hepatology 2004, 40:424-433.
35. Wong B.M., Rodri{dotless}́guez S.N., Alejo P.L.J., Perez F.M. Actividad de la Indigofera suffruticosa Mill en la epilepsia crónica experimental y su relación con aminoácidos neurotransmissores. Rev. Cubana Plantas Med. 1999, 1:18-21.
36. Xie Q.W., Kashiwabara Y., Nathan C. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J. Biol. Chem. 1994, 269:4705-4708.
37. Yao H.T., Lin J.H., Chiang M.T., Chiang W., Luo M.N., Lii C.K. Suppressive effect of the ethanolic extract of adlay bran on cytochrome P-450 enzymes in rat liver and lungs. J. Agric. Food Chem. 2011, 59:4306-4314.