메뉴 건너뛰기




Volumn 98, Issue 2, 2013, Pages

Beclin 1 enhances proteasome inhibition-mediated cytotoxicity of thyroid cancer cells in macroautophagy-independent manner

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; BECLIN 1; BORTEZOMIB; EPOXOMICIN; LACTACYSTIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEASOME; SHORT HAIRPIN RNA; SURVIVIN; WORTMANNIN;

EID: 84873669786     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-2679     Document Type: Article
Times cited : (12)

References (42)
  • 3
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer. 2004;4:349-360.
    • (2004) Nat Rev Cancer. , vol.4 , pp. 349-360
    • Adams, J.1
  • 4
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell. 2004; 6:463-477.
    • (2004) Dev Cell. , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 6
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol. 2007;8:741-752.
    • (2007) Nat Rev Mol Cell Biol. , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 7
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. Embo J. 2000;19:5720-5728.
    • (2000) Embo J. , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3
  • 8
    • 0035863399 scopus 로고    scopus 로고
    • A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
    • Paglin S, Hollister T, Delohery T, et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res. 2001;61:439-444.
    • (2001) Cancer Res. , vol.61 , pp. 439-444
    • Paglin, S.1    Hollister, T.2    Delohery, T.3
  • 9
    • 77449157041 scopus 로고    scopus 로고
    • Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagymediated proteolysis in human retinal pigment epithelial cells
    • Ryhanen T, Hyttinen JM, Kopitz J, et al. Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagymediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med. 2009;13:3616-3631.
    • (2009) J Cell Mol Med. , vol.13 , pp. 3616-3631
    • Ryhanen, T.1    Hyttinen, J.M.2    Kopitz, J.3
  • 10
    • 65549139675 scopus 로고    scopus 로고
    • Regulation of the aging process by autophagy
    • Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol Med. 2009;15:217-224.
    • (2009) Trends Mol Med. , vol.15 , pp. 217-224
    • Salminen, A.1    Kaarniranta, K.2
  • 11
    • 41549114279 scopus 로고    scopus 로고
    • The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease
    • Pan T, Kondo S, Le W, Jankovic J. The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain. 2008;131:1969-1978.
    • (2008) Brain. , vol.131 , pp. 1969-1978
    • Pan, T.1    Kondo, S.2    Le, W.3    Jankovic, J.4
  • 12
    • 34250171697 scopus 로고    scopus 로고
    • Autophagy induction rescues toxicity mediated by proteasome inhibition
    • Rubinsztein DC. Autophagy induction rescues toxicity mediated by proteasome inhibition. Neuron. 2007;54:854-856.
    • (2007) Neuron. , vol.54 , pp. 854-856
    • Rubinsztein, D.C.1
  • 13
    • 34548299555 scopus 로고    scopus 로고
    • Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
    • Ding WX, NiHM, Gao W, et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol. 2007;171:513-524.
    • (2007) Am J Pathol. , vol.171 , pp. 513-524
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3
  • 14
    • 33846320884 scopus 로고    scopus 로고
    • The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones
    • Fortun J, Verrier JD, Go JC, Madorsky I, Dunn WA, Notterpek L. The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones. Neurobiol Dis. 2007;25:252-265.
    • (2007) Neurobiol Dis. , vol.25 , pp. 252-265
    • Fortun, J.1    Verrier, J.D.2    Go, J.C.3    Madorsky, I.4    Dunn, W.A.5    Notterpek, L.6
  • 15
    • 66249085237 scopus 로고    scopus 로고
    • The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib
    • Milani M, Rzymski T, Mellor HR, et al. The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. Cancer Res. 2009;69:4415-4423.
    • (2009) Cancer Res. , vol.69 , pp. 4415-4423
    • Milani, M.1    Rzymski, T.2    Mellor, H.R.3
  • 16
    • 48349087467 scopus 로고    scopus 로고
    • Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells
    • Wu WK, Wu YC, Yu L, Li ZJ, Sung JJ, Cho CH. Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells. Biochem Biophys Res Commun. 2008; 374:258-263.
    • (2008) Biochem Biophys Res Commun. , vol.374 , pp. 258-263
    • Wu, W.K.1    Wu, Y.C.2    Yu, L.3    Li, Z.J.4    Sung, J.J.5    Cho, C.H.6
  • 17
    • 42349091446 scopus 로고    scopus 로고
    • Role of the aggresome pathway in cancer: Targeting histone deacetylase 6-dependent protein degradation
    • Rodriguez-Gonzalez A, Lin T, Ikeda AK, Simms-Waldrip T, Fu C, Sakamoto KM. Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation. Cancer Res. 2008;68:2557-2560.
    • (2008) Cancer Res. , vol.68 , pp. 2557-2560
    • Rodriguez-Gonzalez, A.1    Lin, T.2    Ikeda, A.K.3    Simms-Waldrip, T.4    Fu, C.5    Sakamoto, K.M.6
  • 18
    • 11144221007 scopus 로고    scopus 로고
    • Apoptotic and autophagic cell death induced by histone deacetylase inhibitors
    • Shao Y, Gao Z, Marks PA, Jiang X. Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci U S A. 2004;101:18030-18035.
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , pp. 18030-18035
    • Shao, Y.1    Gao, Z.2    Marks, P.A.3    Jiang, X.4
  • 19
    • 0344640906 scopus 로고    scopus 로고
    • Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
    • Haggarty SJ, Koeller KM, Wong JC, Grozinger CM, Schreiber SL. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc Natl Acad Sci U S A. 2003;100:4389-4394.
    • (2003) Proc Natl Acad Sci U S A. , vol.100 , pp. 4389-4394
    • Haggarty, S.J.1    Koeller, K.M.2    Wong, J.C.3    Grozinger, C.M.4    Schreiber, S.L.5
  • 20
    • 0001488499 scopus 로고    scopus 로고
    • Protection against fatal Sindbis virus encephalitis by Beclin, a novel Bcl-2-interacting protein
    • Liang XH, Kleeman LK, Jiang HH, et al. Protection against fatal Sindbis virus encephalitis by Beclin, a novel Bcl-2-interacting protein. J Virol. 1998;72:8586-8596.
    • (1998) J Virol. , vol.72 , pp. 8586-8596
    • Liang, X.H.1    Kleeman, L.K.2    Jiang, H.H.3
  • 21
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell. 2005;122:927-939.
    • (2005) Cell. , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3
  • 22
    • 19944434059 scopus 로고    scopus 로고
    • Inhibition of macroautophagy triggers apoptosis
    • Boya P, Gonzalez-Polo RA, Casares N, et al. Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol. 2005;25:1025-1040.
    • (2005) Mol Cell Biol. , vol.25 , pp. 1025-1040
    • Boya, P.1    Gonzalez-Polo, R.A.2    Casares, N.3
  • 23
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132:27-42.
    • (2008) Cell. , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 24
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by Beclin 1
    • Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by Beclin 1. Nature. 1999;402:672-676.
    • (1999) Nature , vol.402 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3
  • 25
    • 9144240441 scopus 로고    scopus 로고
    • Promotion of tumorigenesis by heterozygous disruption of the Beclin 1 autophagy gene
    • Qu X, Yu J, Bhagat G, et al. Promotion of tumorigenesis by heterozygous disruption of the Beclin 1 autophagy gene. J Clin Invest. 2003;112:1809-1820.
    • (2003) J Clin Invest. , vol.112 , pp. 1809-1820
    • Qu, X.1    Yu, J.2    Bhagat, G.3
  • 27
    • 47249094223 scopus 로고    scopus 로고
    • Role of noncanonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
    • Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R. Role of noncanonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ. 2008; 15:1318-1329.
    • (2008) Cell Death Differ. , vol.15 , pp. 1318-1329
    • Scarlatti, F.1    Maffei, R.2    Beau, I.3    Codogno, P.4    Ghidoni, R.5
  • 28
    • 78649271745 scopus 로고    scopus 로고
    • Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound
    • Tian S, Lin J, Jun Zhou J, et al. Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound, Z18. Autophagy. 2010;6:1032-1041.
    • (2010) Z18. Autophagy. , vol.6 , pp. 1032-1041
    • Tian, S.1    Lin, J.2    Jun Zhou, J.3
  • 29
    • 33847048316 scopus 로고    scopus 로고
    • Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
    • Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu CT. Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol. 2007;170:75-86.
    • (2007) Am J Pathol. , vol.170 , pp. 75-86
    • Zhu, J.H.1    Horbinski, C.2    Guo, F.3    Watkins, S.4    Uchiyama, Y.5    Chu, C.T.6
  • 30
    • 35848947235 scopus 로고    scopus 로고
    • Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: Implications for neurodegeneration and cell death
    • Chu CT, Zhu J, Dagda R. Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death. Autophagy. 2007;3:663-666.
    • (2007) Autophagy. , vol.3 , pp. 663-666
    • Chu, C.T.1    Zhu, J.2    Dagda, R.3
  • 31
    • 58149104300 scopus 로고    scopus 로고
    • Non-canonical autophagy: An exception or an underestimated form of autophagy?
    • Scarlatti F, Maffei R, Beau I, Ghidoni R, Codogno P. Non-canonical autophagy: an exception or an underestimated form of autophagy? Autophagy. 2008;4:1083-1085.
    • (2008) Autophagy. , vol.4 , pp. 1083-1085
    • Scarlatti, F.1    Maffei, R.2    Beau, I.3    Ghidoni, R.4    Codogno, P.5
  • 32
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. Methods for monitoring autophagy. Int J Biochem Cell Biol. 2004;36:2491-2502.
    • (2004) Int J Biochem Cell Biol. , vol.36 , pp. 2491-2502
    • Mizushima, N.1
  • 33
    • 33746108329 scopus 로고    scopus 로고
    • Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
    • Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy. 2005;1:84-91.
    • (2005) Autophagy. , vol.1 , pp. 84-91
    • Tanida, I.1    Minematsu-Ikeguchi, N.2    Ueno, T.3    Kominami, E.4
  • 34
    • 0347986620 scopus 로고    scopus 로고
    • Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes
    • Tassa A, Roux MP, Attaix D, Bechet DM. Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes. Biochem J. 2003;376: 577-586.
    • (2003) Biochem J. , vol.376 , pp. 577-586
    • Tassa, A.1    Roux, M.P.2    Attaix, D.3    Bechet, D.M.4
  • 35
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer. 2005;5:726-734.
    • (2005) Nat Rev Cancer. , vol.5 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 36
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: Their role in cell survival and cell death
    • Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12 Suppl. 2005;2:1509-1518.
    • (2005) Cell Death Differ 12 Suppl. , vol.2 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 37
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science. 2000;290:1717-1721.
    • (2000) Science. , vol.290 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 38
    • 34147193472 scopus 로고    scopus 로고
    • Cell biology: Autophagy and cancer
    • Levine B. Cell biology: autophagy and cancer. Nature. 2007;446: 745-747.
    • (2007) Nature , vol.446 , pp. 745-747
    • Levine, B.1
  • 39
    • 38949108670 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
    • Klionsky DJ, Abeliovich H, Agostinis P, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008;4:151-175.
    • (2008) Autophagy. , vol.4 , pp. 151-175
    • Klionsky, D.J.1    Abeliovich, H.2    Agostinis, P.3
  • 40
    • 0344142468 scopus 로고    scopus 로고
    • Cloning and genomic organization of Beclin 1, a candidate tumor suppressor gene on chromosome 17q21
    • Aita VM, Liang XH, Murty VV, et al. Cloning and genomic organization of Beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics. 1999;59:59-65.
    • (1999) Genomics. , vol.59 , pp. 59-65
    • Aita, V.M.1    Liang, X.H.2    Murty, V.V.3
  • 41
    • 77953358737 scopus 로고    scopus 로고
    • Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells
    • Sun Y, Liu JH, Jin L, et al. Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells. Cancer Lett. 2010;294:204-210.
    • (2010) Cancer Lett. , vol.294 , pp. 204-210
    • Sun, Y.1    Liu, J.H.2    Jin, L.3
  • 42
    • 77955663516 scopus 로고    scopus 로고
    • Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis
    • Niu TK, Cheng Y, Ren X, Yang JM. Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. FEBS Lett. 2010;584:3519-3524.
    • (2010) FEBS Lett. , vol.584 , pp. 3519-3524
    • Niu, T.K.1    Cheng, Y.2    Ren, X.3    Yang, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.