A Parent-of-Origin Effect Determines the Susceptibility of a Non-Informative F1 Population to Trypanosoma cruzi Infection In Vivo

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Silva, Grace K ^a   Cunha, Larissa D ^a   Horta, Catarina V ^a   Silva, Alexandre L N ^a   Gutierrez, Fredy R S ^a,b   Silva, João S ^a   Zamboni, Dario S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b CENTRO DE INVESTIGACIONES   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

A J MOUSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CHAGAS DISEASE; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; HISTOPATHOLOGY; IN VIVO STUDY; INFECTION SENSITIVITY; MACROPHAGE; MALE; MORTALITY; MOUSE; NONHUMAN; PARASITEMIA; PHENOTYPE; SEX DIFFERENCE; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; DISEASE SUSCEPTIBILITY; FEMALE; GENETIC LOCI; HYBRIDIZATION, GENETIC; MALE; MICE; PHENOTYPE; SEX CHARACTERISTICS; SPECIES SPECIFICITY; TRYPANOSOMA CRUZI; X CHROMOSOME;

EID: 84873640496     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056347     Document Type: Article

References (45)

1. Chapman SJ, Hill AV, (2012) Human genetic susceptibility to infectious disease. Nature Reviews Genetics 13: 175-188.
2. Villasenor-Cardoso MI, Ortega E, (2011) Polymorphisms of innate immunity receptors in infection by parasites. Parasite Immunology 33: 643-653.
3. Goodhead I, Archibald A, Amwayi P, Brass A, Gibson J, et al. (2010) A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice. PLoS Neglected Tropical Diseases 4: e880.
4. Sima M, Havelkova H, Quan L, Svobodova M, Jarosikova T, et al. (2011) Genetic control of resistance to Trypanosoma brucei brucei infection in mice. PLoS Neglected Tropical Diseases 5: e1173.
5. WHO (2007) Report of the scientific working group on Chagas disease.
6. Morel CM, Lazdins J, (2003) Chagas disease. Nature Reviews Microbiology 1: 14-15.
7. Rassi A Jr, Rassi A, Marin-Neto JA, (2010) Chagas disease. Lancet 375: 1388-1402.
8. Taylor MC, Huang H, Kelly JM, (2011) Genetic techniques in Trypanosoma cruzi. Advances in Parasitology 75: 231-250.
9. Teixeira SM, daRocha WD, (2003) Control of gene expression and genetic manipulation in the Trypanosomatidae. Genetics and Molecular Research: GMR 2: 148-158.
10. Gibson W, Stevens J, (1999) Genetic exchange in the trypanosomatidae. Advances in Parasitology 43: 1-46.
11. Machado CR, Augusto-Pinto L, McCulloch R, Teixeira SM, (2006) DNA metabolism and genetic diversity in Trypanosomes. Mutation Research 612: 40-57.
12. Williams-Blangero S, Criscione CD, VandeBerg JL, Correa-Oliveira R, Williams KD, et al. (2012) Host genetics and population structure effects on parasitic disease. Philosophical transactions of the Royal Society of London Series B, Biological Sciences 367: 887-894.
13. Clapcott SJ, Teale AJ, Kemp SJ, (2000) Evidence for genomic imprinting of the major QTL controlling susceptibility to trypanosomiasis in mice. Parasite Immunology 22: 259-263.
14. Iraqi F, Clapcott SJ, Kumari P, Haley CS, Kemp SJ, et al. (2000) Fine mapping of trypanosomiasis resistance loci in murine advanced intercross lines. Mamm Genome 11: 645-648.
15. Noyes H, Brass A, Obara I, Anderson S, Archibald AL, et al. (2011) Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection. Proceedings of the National Academy of Sciences of the United States of America 108: 9304-9309.
16. O'Gorman GM, Park SD, Hill EW, Meade KG, Coussens PM, et al. (2009) Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility. BMC Genomics 10: 207.
17. Sturm NR, Campbell DA, (2010) Alternative lifestyles: the population structure of Trypanosoma cruzi. Acta Tropica 115: 35-43.
18. Graefe SE, Streichert T, Budde BS, Nurnberg P, Steeg C, et al. (2006) Genes from Chagas susceptibility loci that are differentially expressed in T. cruzi-resistant mice are candidates accounting for impaired immunity. PLoS One 1: e57.
19. Fernandes AB, Mortara RA, (2004) Invasion of MDCK epithelial cells with altered expression of Rho GTPases by Trypanosoma cruzi amastigotes and metacyclic trypomastigotes of strains from the two major phylogenetic lineages. Microbes and Infection 6: 460-467.
20. Ramirez MI, Ruiz Rde C, Araya JE, Da Silveira JF, Yoshida N, (1993) Involvement of the stage-specific 82-kilodalton adhesion molecule of Trypanosoma cruzi metacyclic trypomastigotes in host cell invasion. Infection and Immunity 61: 3636-3641.
21. Zingales B, Andrade SG, Briones MR, Campbell DA, Chiari E, et al. (2009) A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI. Memorias do Instituto Oswaldo Cruz 104: 1051-1054.
22. Aliberti JC, Cardoso MA, Martins GA, Gazzinelli RT, Vieira LQ, et al. (1996) Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infect Immun 64: 1961-1967.
23. Gazzinelli RT, Oswald IP, Hieny S, James SL, Sher A, (1992) The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta. European Journal of Immunology 22: 2501-2506.
24. Silva GK, Gutierrez FR, Guedes PM, Horta CV, Cunha LD, et al. (2010) Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection. Journal of Immunology 184: 1148-1152.
25. Marim FM, Silveira TN, Lima DS Jr, Zamboni DS, (2010) A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells. PLoS One 5: e15263.
26. Cummings KL, Tarleton RL, (2003) Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR. Mol Biochem Parasitol 129: 53-59.
27. Andrade V, Barral-Netto M, Andrade SG, (1985) Patterns of resistance of inbred mice to Trypanosoma cruzi are determined by parasite strain. Brazilian Journal of Medical and Biological Research 18: 499-506.
28. Goncalves da Costa SC, Calabrese KS, Zaverucha do Valle T, Lagrange PH, (2002) Trypanosoma cruzi: infection patterns in intact and athymic mice of susceptible and resistant genotypes. Histology and Histopathology 17: 837-844.
29. Leon JS, Godsel LM, Wang K, Engman DM, (2001) Cardiac myosin autoimmunity in acute Chagas' heart disease. Infection and Immunity 69: 5643-5649.
30. Marinho CR, Bucci DZ, Dagli ML, Bastos KR, Grisotto MG, et al. (2004) Pathology affects different organs in two mouse strains chronically infected by a Trypanosoma cruzi clone: a model for genetic studies of Chagas' disease. Infection and Immunity 72: 2350-2357.
31. Minoprio P, Coutinho A, Spinella S, Hontebeyrie-Joskowicz M, (1991) Xid immunodeficiency imparts increased parasite clearance and resistance to pathology in experimental Chagas' disease. International Immunology 3: 427-433.
32. Minoprio P, el Cheikh MC, Murphy E, Hontebeyrie-Joskowicz M, Coffman R, et al. (1993) Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependent. Journal of Immunology 151: 4200-4208.
33. Laroque A, Min-Oo G, Tam M, Radovanovic I, Stevenson MM, et al. (2012) Genetic control of susceptibility to infection with Plasmodium chabaudi chabaudi AS in inbred mouse strains. Genes and Immunity 13: 155-163.
34. Min-Oo G, Lindqvist L, Vaglenov A, Wang C, Fortin P, et al. (2008) Genetic control of susceptibility to pulmonary infection with Chlamydia pneumoniae in the mouse. Genes and Immunity 9: 383-388.
35. Roberts LJ, Baldwin TM, Speed TP, Handman E, Foote SJ, (1999) Chromosomes X, 9, and the H2 locus interact epistatically to control Leishmania major infection. European Journal of Immunology 29: 3047-3050.
36. Yadav JS, Pradhan S, Kapoor R, Bangar H, Burzynski BB, et al. (2011) Multigenic control and sex bias in host susceptibility to spore-induced pulmonary anthrax in mice. Infection and Immunity 79: 3204-3215.
37. Wunderlich F, Mossmann H, Helwig M, Schillinger G, (1988) Resistance to Plasmodium chabaudi in B10 mice: influence of the H-2 complex and testosterone. Infection and Immunity 56: 2400-2406.
38. Wunderlich F, Marinovski P, Benten WP, Schmitt-Wrede HP, Mossmann H, (1991) Testosterone and other gonadal factor(s) restrict the efficacy of genes controlling resistance to Plasmodium chabaudi malaria. Parasite Immunology 13: 357-367.
39. Krucken J, Dkhil MA, Braun JV, Schroetel RM, El-Khadragy M, et al. (2005) Testosterone suppresses protective responses of the liver to blood-stage malaria. Infection and Immunity 73: 436-443.
40. Barretto AC, Arteaga E, Mady C, Ianni BM, Bellotti G, et al. (1993) Male sex. Prognostic factor in Chagas' disease. Arquivos brasileiros de cardiologia 60: 225-227.
41. Espinosa R, Carrasco HA, Belandria F, Fuenmayor AM, Molina C, et al. (1985) Life expectancy analysis in patients with Chagas' disease: prognosis after one decade (1973-1983). International Journal of Cardiology 8: 45-56.
42. Aliberti JC, Machado FS, Souto JT, Campanelli AP, Teixeira MM, et al. (1999) beta-Chemokines enhance parasite uptake and promote nitric oxide-dependent microbiostatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi. Infection and Immunity 67: 4819-4826.
43. Silva JS, Vespa GN, Cardoso MA, Aliberti JC, Cunha FQ, (1995) Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages. Infection and Immunity 63: 4862-4867.
44. Silva JS, Twardzik DR, Reed SG, (1991) Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta). The Journal of Experimental Medicine 174: 539-545.
45. Silva JS, Machado FS, Martins GA, (2003) The role of nitric oxide in the pathogenesis of Chagas disease. Front Biosci 8: s314-325.