Role of beclin 1-dependent autophagy in cardioprotection of ischemic preconditioning

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 33, Issue 1, 2013, Pages 51-56

  Peng, Wen ^a   Liu, Yi ^b   Xu, Wei Juan ^a   Xia, Qing Hua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN ASIA HEART HOSPITAL   (China)

Author keywords

acute myocardial ischemia reperfusion injury; autophagy; Bcl 2; Beclin 1; ischemic preconditioning

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; BECLIN 1 PROTEIN, RAT; PROTEIN BCL 2;

ANIMAL; ARTICLE; AUTOPHAGY; HEART INFARCTION PREVENTION; MALE; METABOLISM; PATHOLOGY; RAT; REPERFUSION INJURY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL REPERFUSION INJURY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 84873626180     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-013-1070-6     Document Type: Article

References (35)

1. Braunwald E, Kloner RA. Myocardial reperfusion: a double-edged sword? J Clin Invest, 1985,76(5): 1713-1719
2. Depre C, Vatner SF. Cardioprotection in stunned and hibernating myocardium. Heart Fail Rev, 2007,12(3-4): 307-317
3. Kostin S, Pool L, Elsässer A, et al. Myocytes die by multiple mechanisms in failing human hearts. Circ Res, 2003,92(7):715-724
4. Hein S, Arnon E, Kostin S, et al. Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation, 2003,107(7): 984-991
5. Gottlieb RA, Finley KD, Mentzer RM Jr. Cardioprotection requires taking out the trash. Basic Res Cardiol, 2009,104(2):169-180
6. Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell, 2008,132(1):27-42
7. Maiuri MC, Zalckvar E, Kimchi A, et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol, 2007,8(9):741-752
8. Mizushima N, Levine B, Cuervo AM, et al. Autophagy fights disease through cellular self-digestion. Nature, 2008,451(7182):1069-1075
9. Rodriguez-Enriquez S, Kim I, Currin RT, et al. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy, 2006,2(1):39-46
10. Boya P, González-Polo RA, Casares N, et al. Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol, 2005,25(3):1025-1040
11. Lum JJ, Bauer DE, Kong M, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell, 2005,120(2):237-248
12. Lee J, Giordano S, Zhang J. Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J, 2012,441(2):523-540
13. Gustafsson AB, Gottlieb RA. Mechanisms of apoptosis in the heart. J Clin Immunol, 2003,23(6):447-459
14. Hamacher-Brady A, Brady NR, Logue SE, et al. Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ, 2007,14(1):146-157
15. Yan L, Vatner DE, Kim SJ, et al. Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci USA, 2005,102(39):13 807-13 812
16. Hamacher-Brady A, Brady NR, Gottlieb RA. Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes. J Biol Chem, 2006,281(40): 29 776-29 787
17. Ryter SW, Lee SJ, Smith A, et al. Autophagy in vascular disease. Proc Am Thorac Soc, 2010,7(1):40-47
18. Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell, 2005,122(6):927-939
19. Itakura E, Kishi C, Inoue K, et al. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell, 2008,19(12):5360-5372
20. Furuya N, Yu J, Byfield M, et al. The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy, 2005,1(1):46-52
21. Oberstein A, Jeffrey PD, Shi Y. Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem, 2007,282(17):13 123-13 132
22. Maiuri MC, Le Toumelin G, Criollo A, et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin1. EMBO J, 2007,26(10): 2527-2539
23. Oh S, Xiaofei E, Ni D, et al. Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis. Cell Death Differ, 2011,18(3):452-464
24. Huang C, Yitzhaki S, Perry CN, et al. Autophagy induced by ischemic preconditioning is essential for cardioprotection. J Cardiovasc Transl Res, 2010,3(4):365-373
25. Yang X, Cohen MV, Downey JM. Mechanism of cardioprotection by early ischemic preconditioning. Cardiovasc Drugs Ther, 2010,24(3):225-234
26. Downey JM, Krieg T, Cohen MV. Mapping preconditioning's signaling pathways: an engineering approach. Ann N Y Acad Sci, 2008,1123:187-196
27. Jones SP, Bolli R. The ubiquitous role of nitric oxide in cardioprotection. J Mol Cell Cardiol, 2006,40(1):16-23
28. Pain T, Yang XM, Critz SD, et al. Opening of mitochondrial K (ATP) channels triggers the preconditioned state by generating free radicals. Circ Res, 2000,87(6):460-466
29. Matsui Y, Takagi H, Qu X, et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res, 2007,100(6):914-922
30. Brocheriou V, Hagège AA, Oubenaïssa A. Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury. J Gene Med, 2000,2(5):326-333
31. Imahashi K, Schneider MD, Steenbergen C. Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolicacidification during ischemia, and reduces ischemia/reperfusion injury. Circ Res, 2004,95 (7):734-741
32. Hochhauser E, Kivity S, Offen D, et al. Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice. Am J Physiol Heart Circ Physiol, 2003,284(6):H2351-H2359
33. Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy, 2008,4(5):600-606
34. Liang C, Feng P, Ku B, et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol, 2006,8(7):688-699
35. Zhu Y, Zhao L, Liu L, et al. Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell, 2010,1(5):468-477