NMDA and AMPA receptor mediated excitotoxicity in cerebral cortex of streptozotocin induced diabetic rat: Ameliorating effects of curcumin

Chemico-Biological Interactions

Volumn 201, Issue 1-3, 2013, Pages 39-48

  Jayanarayanan, S ^a   Smijin, S ^a   Peeyush, K T ^a,b   Anju, T R ^a   Paulose, C S ^a  

^a Department of Physics   (India)

^b MCLEAN HOSPITAL   (United States)

Author keywords

AMPA; Cerebral cortex; Curcumin; Diabetes mellitus; Insulin; NMDA

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLE PROPIONATE; AMPA RECEPTOR; CASPASE 3; CASPASE 8; CURCUMIN; EXCITATORY AMINO ACID TRANSPORTER; GLUCOSE; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; INSULIN; INSULIN ZINC SUSPENSION; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROPIONIC ACID DERIVATIVE; PROTEIN BAX; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CORTEX; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; DRUG EFFECT; EXCITOTOXICITY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; MALE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DENSITY; STREPTOZOCIN DIABETES;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CEREBRAL CORTEX; CURCUMIN; DIABETES MELLITUS, EXPERIMENTAL; GLUTAMATE DECARBOXYLASE; MALE; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER;

EID: 84873616902     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.11.024     Document Type: Article

References (72)

1. P. Daisy, K. Santhosh, and M. Rajathi Antihyperglycemic and antihyperlipidemic effects of Clitoria ternatea Linn. in alloxan induced diabetic rats Afr. J. Microbiol. Res. 3 2009 287 291
2. A.M. Brands, J.M. Henselmans, E.H. de Haan, and G.J. Biessels Diabetic encephalopathy: an underexposed complication of diabetes mellitus Ned. Tijdschr. Geneeskd. 147 2003 11 14
3. G.S. Mijnhout, P. Scheltens, M. Diamant, G.J. Biessels, A.M. Wessels, S. Simsek, F.J. Snoek, and R.J. Heine Diabetic encephalopathy: a concept in need of a definition Diabetologia 49 2006 1447 1448
4. D. Bonnefont-Rousselot Glucose and reactive oxygen species Curr. Opin. Clin. Nutr. Metab. Care 5 2002 561 568
5. A. Ceriello New insights on oxidative stress and diabetic complications may lead to a "Causal" antioxidant therapy Diabetes Care 26 2003 1589 1596
6. R. Mastrocola, F. Restivo, I. Vercellinatto, O. Danni, E. Brignar-dello, M. Aragno, and G. Boccuzzi Oxidative and nitrosative stress in brain mitochondria of diabetic rats J. Endocrinol. 187 2005 37 44
7. J.R. Drevet The antioxidant glutathione peroxidase family and spermatozoa: a complex story Mol. Cell. Endocrinol. 250 2006 70 79
8. S.K. Bhardwaj, S.K. Sandhu, P. Sharma, and G. Kaur Impact of diabetes on CNS: role of signal transduction cascade Brain Res. Bull. 49 1999 155 162
9. S. Gill, and O. Pulido Glutamate receptors in peripheral tissues: current knowledge, future research, and implications for toxicology Toxicol. Pathol. 29 2001 208 223
10. E. Roberts, and K. Kuriyama Bio chemical-physiological correlations in studies of the 7-aminobutyric acid system Brain Res. 8 1968 1 35
11. M.N. Delyfer, V. Forster, N. Neveux, S. Picaud, T. Leveillard, and J.A. Sahel Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina Mol. Vis. 11 2005 688 696
12. C. Chabot, G. Massicotte, M. Milot, F. Trudeau, and J. Gagne Impaired modulation of AMPA receptors by calcium-dependent processes in streptozotocin-induced diabetic rats Brain Res. 768 1997 249 256
13. D. Trotti, N.C. Danbolt, and A. Volterra Glutamate transporters are oxidant vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci. 19 1998 328 334
14. J. Dunlop Glutamate-based therapeutic approaches: targeting the glutamate transport system Curr. Opin. Pharmacol. 6 2006 103 107
15. Y.M. Zhang, X.F. Lu, and B.R. Bhavnani Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death BMC Neurosci. 4 2003 32
16. Y. Hirashima, M. Kurimoto, K. Nogami, S. Endo, M. Saitoh, O. Ohtani, T. Nagata, A. Muraguchi, and A. Takaku Correlation of glutamate-induced apoptosis with caspase activities in cultured rat cerebral cortical neurons Brain Res. 849 1999 109 118
17. V.E. Kagan, and Y.Y. Tyurina Recycling and redox cycling of phenolic antioxidants Ann. N. Y. Acad. Sci. 854 1998 425 434
18. X. Gao, J. Kuo, H. Jiang, D. Deeb, Y. Liu, G. Divine, R.A. Chapman, S.A. Dulchavsky, and S.C. Gautam Immunomodulatory activity of curcumin, suppression of lymphocyte proliferation, development of cell mediated cytotoxicity, and cytokine production in vitro Biochem. Pharmacol. 68 2004 51 61
19. B. Joe, M. Vijaykumar, and B.R. Lokesh Biological properties of curcumin-cellular and molecular mechanisms of action Crit. Rev. Food Sci. Nutr. 44 2004 97 111
20. S.P. Weisberg, R. Leibel, and D.V. Tortoriello Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity Endocrinology 149 2008 3549 3558
21. W. Shao, Z. Yu, Y. Chiang, Y. Yang, T. Chai, W. Foltz, H. Lu, I.G. Fantus, and T. Jin Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes PLoS ONE 7 2012 e28784
22. M. Kuroda, Y. Mimaki, T. Nishiyama, T. Mae, H. Kishida, M. Tsukagawa, K. Takahashi, T. Kawada, K. Nakagawa, and M. Kitahara Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice Biol. Pharm. Bull. 28 2005 937 939
23. T. Nishiyama, T. Mae, H. Kishida, M. Tsukagawa, Y. Mimaki, M. Kuroda, Y. Sashida, K. Takahashi, T. Kawada, K. Nakagawa, and M. Kitahara Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice J. Agric. Food Chem. 53 2005 959 963
24. S.K. Jain, J. Rains, J. Croad, B. Larson, and K. Jones Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNFalpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats Antioxid. Redox Signal. 11 2009 241 249
25. A. Jacob, R. Wu, M. Zhou, and P. Wang Mechanism of the anti-inflammatory effect of curcumin: PPAR-gamma activation PPAR Res. 2007 2007 89369
26. M. Kanitkar, K. Gokhale, S. Galande, and R.R. Bhonde Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo Br. J. Pharmacol. 155 2008 702 713
27. K.I. Seo, M.S. Choi, U.J. Jung, H.J. Kim, J. Yeo, S.M. Jeon, and M.K. Lee Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice Mol. Nutr. Food Res. 52 2008 995 1004
28. E.M. Jang, M.S. Choi, U.J. Jung, M.J. Kim, H.J. Kim, S.M. Jeon, S.K. Shin, C.N. Seong, and M.K. Lee Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters Metabolism 57 2008 1576 1583
29. J.N.M. Commandeur, and N.P.E. Vermeulen Cytotoxicity and cytoprotective activities of natural compounds the case of curcumin Xenobiotica 26 1996 667 680
30. Y.J. Surh, K.S. Chun, H.H. Cha, S.S. Han, Y.S. Keum, K.K. Park, and S.S. Lee Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals, down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation Mutat. Res. 480 2001 243 268
31. J.S.M. Miller, F.M. Angeles, B.K. Reuter, P. Bobrowski, and M. Sandoval Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis BMC Complement. Altern. Med. 1 2001 11
32. S. Sharma, S.K. Kulkarni, and K. Chopra Curcumin, the active principle of turmeric (Curcuma longa), ameliorates diabetic nephropathy in rats Clin. Exp. Pharmacol. Physiol. 33 2006 940 945
33. R.A. Kowluru, and M. Kanwar Effects of curcumin on retinal oxidative stress and inflammation in diabetes Nutr. Metab. 4 2007 8 12
34. G.B. Sajithal, P. Chithra, and G. Chandrakasan Effect of curcumin on the advanced glycation and cross-linking of collagen in diabetic rats Biochem. Pharmacol. 56 1998 1607 1614
35. A. Junod, A.E. Lambert, W. Staufferacher, and A.E. Renold Diabetogenic action of Streptozotoc: relationship of dose to metabolic response J. Clin. Invest. 48 1969 2129 2139
36. M. Hohenegger, and B. Rudas Kidney function in experimental diabetic ketosis Diabetologia 7 1971 334 338
37. R.N. Arison, E.I. Ciaccio, M.S. Glitzer, J.A. Cassaro, and M.P. Pruss Light and electron microscopy of lesions in rats rendered diabetic with streptozotocin Diabetes 16 1967 51 56
38. S. Sharma, K. Chopra, and S.K. Kulkarni Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF-alpha Phytother. Res. 21 2007 278 283
39. J. Glowinski, and L.L. Iversen Regional studies of catecholamines in the rat brain, the disposition of [3H] norepinephrine, [3H]dopa in various regions of brain J. Neurochem. 13 1966 655 669
40. D.J. Hoffman, S.A. Zanelli, J.M. Kubin, P. Om, and P.M. Delivoria The in vivo effect of bilirubin on the N-methyl-d-aspartate receptor/ion channel complex in the brains of newborn piglets Pediatr. Res. 40 1996 804 808
41. G. Scatchard The attraction of proteins for small molecules and ions Ann. N. Y. Acad. Sci. 51 1949 660 672
42. O.H. Lowry, N.J. Roserbbrough, A.L. Farr, and R.J. Randall Protein measurement with Folin phenol reagent J. Biol. Chem. 193 1951 265 275
43. S.J. Enna, and S.H. Snyder A simple, sensitive and specific radioreceptor assay for endogenous GABA in brain tissue J. Neurochem. 26 1976 221 224
44. S. Chen, M. Kobayashi, Y. Honda, S. Kakuta, F. Sato, and K. Kishi Preferential neuron loss in rat piriform cortex following pilocarpine induced status epilepticus Epilepsy Res. 74 2007 1 18
45. K. Meghana, G. Sanjeev, and B. Ramesh Curcumin prevents streptozotocin induced islet damage by scavenging free radicals: a prophylactic and protective role Eur. J. Pharmacol. 577 2007 183 191
46. H. Katagiri, K. Tanaka, and T. Manabe Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction Eur. J. Neurosci. 14 2001 547 553
47. R.M. Mangano, and R. Schwarcz Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus Brain Res. Bull. 10 1983 47 51
48. G.J. Wang, H.J. Chung, J. Schnuer, E. Lea, M.B. Robinson, W.K. Potthoff, E. Aizenman, and P.A. Rosenberg Dihydrokainate-sensitive neuronal glutamate transport is required for protection of rat cortical neurons in culture against synaptically released glutamate Eur. J. Neurosci. 10 1998 2523 2531
49. J. Anu, T. Peeyush Kumar, M.S. Nandhu, and C.S. Paulose Enhanced NMDAR1, NMDA2B and mGlu5 receptors gene expression in the cerebellum of insulin induced hypoglycaemic and streptozotocin induced diabetic rats Eur. J. Pharmacol. 25 2010 61 68
50. K.A. Rahn, B.S. Slusher, and A.I. Kaplin Glutamate in CNS neurodegeneration and cognition and its regulation by GCPII inhibition Curr. Med. Chem. 19 2012 1335 1345
51. M.R. Hynd, H.L. Scott, and P.R. Dodd Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease Neurochem. Int. 45 5 2004 583 595
52. C.L. Leibson, W.A. Rocca, V.A. Hanson, R. Cha, E. Kokmen, P.C. O'brien, and P.J. Palumbo Risk of dementia among persons with diabetes mellitus: a population-based cohort study Am. J. Epidemiol. 145 1997 301 308
53. M.F. Beal Aging, energy, and oxidative stress in neurodegenerative diseases Ann. Neurol. 38 1995 357 366
54. K.D. Sims, and M.B. Robinson Expression patterns and regulation of glutamate transporters in the developing and adult nervous system Crit. Rev. Neurobiol. 13 1999 169 197
55. R.S. Petralia Immunochemical localization of ionotropic glutamate receptors (GluRs) in neural circuits D.T. Monaghan, R.J. Wenthold, The Ionotropic Glutamate Receptors 1997 Humana Totawa, NJ 219 263
56. K.J. Page, and B.J. Everitt The distribution of neurons coexpressing immuno reactivity to AMPA-sensitive glutamate receptor subtypes (GluR1-4) and nerve growth factor receptor in the rat basal forebrain Eur. J. Neurosci. 7 1995 1022 1033
57. 2+ permeability of KA-AMPA-gated glutamate channels depends on subunit composition Science 253 1991 1028 1031
58. D.W. Choi Glutamate neurotoxicity and diseases of the nervous system Neuron 1 1988 623 634
59. D. Giugliano, A. Ceriello, and G. Paoliso Diabetes mellitus, hypertension and cardiovascular disease. Which role for oxidative stress? Metabolism 44 1995 363 368
60. H. Sies Oxidative stress: introductory remarks H. Sies, Oxidative Stress 1985 Academic Press London 1 7
61. S.A. Wohaieb, and D.V. Godin Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment Diabetes 36 1987 1014 1018
62. M. Miranda, M. Muriach, J. Romá, F. Bosch-Morell, J.M. Genovés, J. Barcia, J. Araiz, M. Diaz-Llopis, and F.J. Romero Oxidative stress in a model of experimental diabetic retinopathy. II. Peroxynitrite scavengers utility Arch. Soc. Esp. Oftalmol. 80 2006 27 32
63. K. Zeng, H. Xu, K. Chen, J. Zhu, Y. Zhou, Q. Zhang, and M. Mantian Effects of taurine on glutamate uptake and degradation in Müller cells under diabetic conditions via antioxidant mechanism Mol. Cell. Neurosci. 45 2010 192 199
64. B. Mannervik Glutathione peroxidase Methods Enzymol. 113 1985 490 495
65. F. Ursini, M. Maiorino, R. Brigelius-Flohe, K.D. Aumann, A. Roveri, D. Schomburg, and L. Flohe Diversity of glutathione peroxidases Methods Enzymol. 252 1995 38 53
66. 2+ permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor Cell Death Differ. 13 2006 652 660
67. J.C. Reed Bcl-2 family proteins Oncogene 17 1998 3225 3236
68. S. Cory, and J.M. Adams The Bcl2 family: regulators of the cellular life-or death switch Nat. Rev. Cancer 2 2002 647 656
69. B.M. Polster, and G. Fiskum Mitochondrial mechanisms of neural cell apoptosis J. Neurochem. 90 2004 1281 1289
70. M.W. Ward, D. Kögel, and J.H. Prehn Neuronal apoptosis: BH3-only proteins the real killers? J. Bioenerg. Biomembr. 36 2004 295 298
71. R.U. Janicke, M.L. Sprengart, M.R. Wati, and A.G. Porter Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis J. Biol. Chem. 273 1998 9357 9360
72. E.A. Slee, M.T. Harte, R.M. Kluck, B.B. Wolf, C.A. Casiano, D.D. Newmeyer, H.G. Wang, J.C. Reed, D.W. Nicholson, E.S. Alnemri, D.R. Green, and S.J. Martin Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner J. Cell Biol. 144 1999 281 292