Effects of (-)-cubebin (Piper cubeba) on cytotoxicity, mutagenicity and expression of p38 MAP kinase and GSTa2 in a hepatoma cell line

Journal of Food Composition and Analysis

Volumn 30, Issue 1, 2013, Pages 1-5

  Niwa, Andressa Megumi ^a   Marcarini, Juliana Cristina ^b   Sartori, Daniele ^a   Maistro, Edson Luis ^b   Mantovani, Mário Sérgio ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

( ) Cubebin; Cell proliferation; Cytotoxicity; Food analysis; Food composition; Food safety; HTC cells; Mutagenicity; Piper cubeba

Indexed keywords

PIPER CUBEBA; RATTUS; RATTUS NORVEGICUS;

EID: 84873563743     PISSN: 08891575     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfca.2012.12.003     Document Type: Article

References (30)

1. a ed. Editora da UFRGS/Editora da UFSC, Porto Alegre/Florianópolis, Brasil, pp. 557-575.
2. Bastos J.K., Albuquerque S., Silva M.L.A. Evaluation of the trypanocidal activity of lignans isolated from the leaves of Zanthoxylum naranjillo. Planta Medica 1999, 65:541-544.
3. Bastos J.K., Carvalho J.C.T., De Souza G.H.B., Pedrazzi A.H.P., Sarti S.J. Anti-inflammatory activity of cubebin, a lignan from the leaves of Zanthoxyllum naranjillo Griseb. Journal of Ethnopharmacology 2001, 75:279-282.
4. Bodiwala H.S., Singh G., Singh R., Dey C.S., Sharma S.S., Bhutani K.K., Singh I.P. Antileishmanial amides and lignans from Piper cubeba and Piper retrofractum. Journal of Natural Medicines 2007, 61:418-421.
5. de Rezende A.A.A., e Silva M.L.A., Tavares D.C., Cunha W.R., Rezende K.C.S., Bastos J.K., Lehmann M., de Andrade H.H.R., Guterres Z.R., Silva L.P., Spanó M.A. The effect of the dibenzylbutyrolactolic lignan (-)-cubebin on doxorubicin mutagenicity and recombinogenicity in wing somatic cells of Drosophila melanogaster. Food and Chemical Toxicology 2011, 49:1235-1241.
6. de Souza V.A., Silva R., Pereira A.C., Royo V.A., Saraiva J., Montanheiro M., Souza G.H.B., Filho A.A.S., Grando M.D., Donate P.M., Bastos J.K., Albuquerque S., Silva M.L.A. Trypanocidal activity of (-)-cubebin derivatives against free amastigote forms of Trypanosoma cruzi. Bioorganic & Medicinal Chemistry Letters 2005, 15:303-307.
7. Eastmond D.A., Tucker J.D. Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environmental and Molecular Mutagenesis 1989, 13:34-43.
8. Eaton D.L., Bammler T.K. Concise review of the glutathione S-transferases and their significance to toxicology. Toxicological Sciences 1999, 49:156-164.
9. Esperandim V.R., Ferreira D.S., Rezende K.C.S., Cunha W.R., Saraiva J., Bastos J.K., Silva M.L.A., Albuquerque S. In vivo infection by Trypanosoma cruzi: a morphometric study of tissue changes in mice. Parasitology Research 2013, 112:431-436.
10. Fenech M. The in vitro micronucleus technique. Mutation Research 2000, 455:81-95.
11. Junqueira A.P.F., Perazzo F.F., Souza G.H.B., Maistro E.L. Clastogenicity of Piper cubeba (Piperaceae) seed extract in an in vivo mammalian cell system. Genetics and Molecular Biology 2007, 30:656-663.
12. Krajčová A., Schulzová V., HajŠlová J., Bjelková M. Lignans in flaxseed. Czech Journal of Food Sciences 2009, 27:S252-S255.
13. Maistro E.L., Natel A.V.M., de Souza G.H.B., Perazzo F.F. Genotoxic effects of (-)-cubebin in somatic cells of mice. Journal of applied toxicology 2011, 31:185-189.
14. Martins de Oliveira J., Jordão B.Q., Ribeiro L.R., da Eira A.F., Mantovani M.S. Anti-genotoxic effect of aqueous extracts of sun mushroom (Agaricus blazei Murill lineage 99/26) in mammalian cells in vitro. Food and Chemical Toxicology 2002, 40:1775-1780.
15. Mauro M.O., Sartori D., Oliveira R.J., Ishii P.L., Mantovani M.S., Ribeiro L.R. Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells. Mutation Research 2011, 715:7-12.
16. Medola J.F., Cintra V.P., Silva é.P.P., Royo V.A., Silva R., Saraiva J., Albuquerque S., Bastos J.K., Silva M.L.A.E, Tavares D.C. (-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats. Food and Chemical Toxicology 2007, 45:638-642.
17. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 1983, 65:55-63.
18. New L., Han J. The p38 MAP kinase pathway and its biological function. TCM 1998, 8(5).
19. Nunes J.D., Torres G.A., Davide L.C., Salgado C.C. Citogenética de Piper hispidinervum e Piper aduncum. Pesquisa Agropecuária Brasileira 2007, 42:1049-1052.
20. Ono K., Han J. The p38 signal transduction pathway activation and function. Cellular Signalling 2000, 12:1-13.
21. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Research 2001, 29:2002-2007.
22. Pfaffl M.W., Horgan G.W., Dempfle L. Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Research 2002, 30:1-10.
23. Pickett C.B., Telakowski-Hopkins C.A., Ding G.J., Ding V.D. Expression and sequence analysis of rat liver glutathione S-transferase genes. Advances in Experimental Medicine and Biology 1986, 197:185-193.
24. Resende F.A., Tomazella I.M., Barbosa L.C., Ponce M., Furtado R.A., Pereira A.C., Bastos J.K., Andrade e Silva M.L., Tavares D.C. Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts. Mutation Research 2010, 700:62-66.
25. Sheehan D., Meade G., Foley V.M., Dowd C.A. Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily. Biochemical Journal 2001, 360:1-16.
26. Teixeira R.O., Camparoto M.L., Mantovani M.S., Vicentini V.E.P. Assessment of two medicinal plants, Psidium guajava L. and Achillea millefolium L. in in vitro and in vivo assays. Genetics and Molecular Biology 2003, 26:551-555.
27. Tso J.Y., Sun X.H., Kao T.H., Reece K.S., Wu R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic acids research 1985, 13:2485-2502.
28. Verma N., Pink M., Rettenmeier A.W., Schmitz-Spanke S. Review on proteomic analyses of benzo[a]pyrene toxicity. Proteomics 2012, 12:1731-1755.
29. Yam J., Kreuter M., Drewe J. Piper cubeba targets multiple aspects of the androgen-signalling pathway. A potential phytotherapy against prostate cancer growth?. Planta Medica 2008, 74:33-38.
30. Zarubin T., Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Research 2005, 15:11-18.