Trypanocidal activity of (-)-cubebin derivatives against free amastigote forms of Trypanosoma cruzi

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 2, 2005, Pages 303-307

  De Souza, Vanessa A ^a   Da Silva, Rosangela ^b   Pereira, Ana C ^a   Royo, Vanessa De A ^a,b   Saraiva, Juliana ^b   Montanheiro, Marisa ^b   De Souza, Gustavo H B ^b   Da Silva Filho, Ademar A ^b   Grando, Marcella D ^b   Donate, Paulo M ^c   Bastos, Jairo K ^b   Albuquerque, Sérgio ^b   E Silva, Márcio L A ^a  

^a 2001 CEP: 14404 600 Franca SP B   (Brazil)

^b Faculdade Cie Farmaceuticas R   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Amastigote forms; Cubebin derivatives; Lignans dibenzylbutyrolactones; Trypanocidal activity

Indexed keywords

6,6' DINITROHINOKININ; ANTITRYPANOSOMAL AGENT; HINOKININ; O (N,N DIMETHYLAMINOETHYL)CUBEBIN; O ACETYLCUBEBIN; O BENZYLCUBEBIN; UNCLASSIFIED DRUG;

AMASTIGOTE; ARTICLE; ASSAY; CHAGAS DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; IC 50; IN VITRO STUDY; NONHUMAN; PARASITE; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; INHIBITORY CONCENTRATION 50; LIGNANS; MEMBRANE GLYCOPROTEINS; PARASITIC SENSITIVITY TESTS; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

PIPER CUBEBA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 10644259440     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.10.079     Document Type: Article

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