Is the Present Definition of Health Care-Associated Pneumonia the Best Way to Define Risk of Infection with Antibiotic-Resistant Pathogens?

Infectious Disease Clinics of North America

Volumn 27, Issue 1, 2013, Pages 1-18

  Yap, Vanessa ^a   Datta, Debapriya ^a   Metersky, Mark L ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Antibiotic resistance; Community acquired pneumonia; Health care associated pneumonia; Risk score

Indexed keywords

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; COMORBIDITY; DISEASE SEVERITY; FUNCTIONAL STATUS; HEALTH CARE ASSOCIATED PNEUMONIA; HEMODIALYSIS; HOME CARE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION RISK; LENGTH OF STAY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MONOTHERAPY; MORTALITY; MULTIDRUG RESISTANCE; NONHUMAN; NURSING HOME; OUTCOME ASSESSMENT; REVIEW; RISK ASSESSMENT; WOUND CARE;

ANTI-BACTERIAL AGENTS; COMMUNITY-ACQUIRED INFECTIONS; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; PNEUMONIA, BACTERIAL; RISK FACTORS;

EID: 84873550570     PISSN: 08915520     EISSN: 15579824     Source Type: Journal    
DOI: 10.1016/j.idc.2012.11.002     Document Type: Review

References (53)

1. American Thoracic Society, Infectious Diseases Society of America Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005, 171(4):388-416.
2. Madaras-Kelly K.J., Remington R.E., Sloan K.L., et al. Guideline-based antibiotics and mortality in healthcare-associated pneumonia. J Gen Intern Med 2012, 27(7):845-852.
3. Kett D.H., Cano E., Quartin A.A., et al. Implementation of guidelines for management of possible multidrug-resistant pneumonia in intensive care: an observational, multicentre cohort study. Lancet Infect Dis 2011, 11(3):181-189.
4. Attridge R.T., Frei C.R., Restrepo M.I., et al. Guideline-concordant therapy and outcomes in healthcare-associated pneumonia. Eur Respir J 2011, 38(4):878-887.
5. Schreiber M.P., Chan C.M., Shorr A.F. Resistant pathogens in nonnosocomial pneumonia and respiratory failure: is it time to refine the definition of health-care-associated pneumonia?. Chest 2010, 137(6):1283-1288.
6. Micek S.T., Reichley R.M., Kollef M.H. Health care-associated pneumonia (HCAP): empiric antibiotics targeting methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa predict optimal outcome. Medicine (Baltimore) 2011, 90(6):390-395.
7. Kollef M.H., Shorr A., Tabak Y.P., et al. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest 2005, 128(6):3854-3862.
8. Kollef M.H., Morrow L.E., Baughman R.P., et al. Health care-associated pneumonia (HCAP): a critical appraisal to improve identification, management, and outcomes-proceedings of the HCAP Summit. Clin Infect Dis 2008, 46(Suppl 4):S296-S334. [quiz: 335-8].
9. Ewig S., Welte T., Chastre J., et al. Rethinking the concepts of community-acquired and health-care-associated pneumonia. Lancet Infect Dis 2010, 10(4):279-287.
10. Shindo Y., Sato S., Maruyama E., et al. Health-care-associated pneumonia among hospitalized patients in a Japanese community hospital. Chest 2009, 135(3):633-640.
11. Carratala J., Mykietiuk A., Fernandez-Sabe N., et al. Health care-associated pneumonia requiring hospital admission: epidemiology, antibiotic therapy, and clinical outcomes. Arch Intern Med 2007, 167(13):1393-1399.
12. Venditti M., Falcone M., Corrao S., et al. Outcomes of patients hospitalized with community-acquired, health care-associated, and hospital-acquired pneumonia. Ann Intern Med 2009, 150(1):19-26.
13. Rello J., Lujan M., Gallego M., et al. Why mortality is increased in health-care-associated pneumonia: lessons from pneumococcal bacteremic pneumonia. Chest 2010, 137(5):1138-1144.
14. Carratala J., Garcia-Vidal C. What is healthcare-associated pneumonia and how is it managed?. Curr Opin Infect Dis 2008, 21(2):168-173.
15. Park H.K., Song J.U., Um S.W., et al. Clinical characteristics of health care-associated pneumonia in a Korean teaching hospital. Respir Med 2010, 104(11):1729-1735.
16. Chalmers J.D., Taylor J.K., Singanayagam A., et al. Epidemiology, antibiotic therapy, and clinical outcomes in health care-associated pneumonia: a UK cohort study. Clin Infect Dis 2011, 53(2):107-113.
17. Lim W.S., Baudouin S.V., George R.C., et al. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax 2009, 64(Suppl 3):iii1-iii55.
18. Park S.C., Kang Y.A., Park B.H., et al. Poor prediction of potentially drug-resistant pathogens using current criteria of health care-associated pneumonia. Respir Med 2012, 106(9):1311-1319.
19. Poch D.S., Ost D.E. What are the important risk factors for healthcare-associated pneumonia?. Semin Respir Crit Care Med 2009, 30(1):26-35.
20. Labelle A.J., Arnold H., Reichley R.M., et al. A comparison of culture-positive and culture-negative health-care-associated pneumonia. Chest 2010, 137(5):1130-1137.
21. Friedman N.D., Kaye K.S., Stout J.E., et al. Health care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med 2002, 137(10):791-797.
22. Gaynes R. Health care-associated bloodstream infections: a change in thinking. Ann Intern Med 2002, 137(10):850-851.
23. Ewig S., Klapdor B., Pletz M.W., et al. Nursing-home-acquired pneumonia in Germany: an 8-year prospective multicentre study. Thorax 2012, 67(2):132-138.
24. Attridge R.T., Frei C.R. Health care-associated pneumonia: an evidence-based review. Am J Med 2011, 124(8):689-697.
25. Brito V., Niederman M.S. Healthcare-associated pneumonia is a heterogeneous disease, and all patients do not need the same broad-spectrum antibiotic therapy as complex nosocomial pneumonia. Curr Opin Infect Dis 2009, 22(3):316-325.
26. Sugisaki M., Enomoto T., Shibuya Y., et al. Clinical characteristics of healthcare-associated pneumonia in a public hospital in a metropolitan area of Japan. J Infect Chemother 2012, 18(3):352-360.
27. Polverino E., Dambrava P., Cilloniz C., et al. Nursing home-acquired pneumonia: a 10 year single-centre experience. Thorax 2010, 65(4):354-359.
28. Ewig S., Welte T., Torres A. Is healthcare-associated pneumonia a distinct entity needing specific therapy?. Curr Opin Infect Dis 2012, 25(2):166-175.
29. El-Solh A.A., Sikka P., Ramadan F., et al. Etiology of severe pneumonia in the very elderly. Am J Respir Crit Care Med 2001, 163(3 Pt 1):645-651.
30. El Solh A.A., Pietrantoni C., Bhat A., et al. Indicators of potentially drug-resistant bacteria in severe nursing home-acquired pneumonia. Clin Infect Dis 2004, 39(4):474-480.
31. Maruyama T., Niederman M.S., Kobayashi T., et al. A prospective comparison of nursing home-acquired pneumonia with hospital-acquired pneumonia in non-intubated elderly. Respir Med 2008, 102(9):1287-1295.
32. Umeki K., Tokimatsu I., Yasuda C., et al. Clinical features of healthcare-associated pneumonia (HCAP) in a Japanese community hospital: comparisons among nursing home-acquired pneumonia (NHAP), HCAP other than NHAP, and community-acquired pneumonia. Respirology 2011, 16(5):856-861.
33. Klapdor B., Ewig S., Schaberg T., et al. Presentation, etiology and outcome of pneumonia in younger nursing home residents. J Infect 2012, 65(1):32-38.
34. Garcia-Vidal C., Viasus D., Roset A., et al. Low incidence of multidrug-resistant organisms in patients with healthcare-associated pneumonia requiring hospitalization. Clin Microbiol Infect 2011, 17(11):1659-1665.
35. Depuydt P., Putman B., Benoit D., et al. Nursing home residence is the main risk factor for increased mortality in healthcare-associated pneumonia. J Hosp Infect 2011, 77(2):138-142.
36. Mandell L.A., Wunderink R.G., Anzueto A., et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007, 44(Suppl 2):S27-S72.
37. Loeb M., Carusone S.C., Goeree R., et al. Effect of a clinical pathway to reduce hospitalizations in nursing home residents with pneumonia: a randomized controlled trial. JAMA 2006, 295(21):2503-2510.
38. Wakasugi M., Kawamura K., Yamamoto S., et al. High mortality rate of infectious diseases in dialysis patients: a comparison with the general population in Japan. Ther Apher Dial 2012, 16(3):226-231.
39. Slinin Y., Foley R.N., Collins A.J. Clinical epidemiology of pneumonia in hemodialysis patients: the USRDS waves 1, 3, and 4 study. Kidney Int 2006, 70(6):1135-1141.
40. Wakino S., Imai E., Yoshioka K., et al. Clinical importance of Stenotrophomonas maltophilia nosocomial pneumonia due to its high mortality in hemodialysis patients. Ther Apher Dial 2009, 13(3):193-198.
41. Guo H., Liu J., Collins A.J., et al. Pneumonia in incident dialysis patients-the United States Renal Data System. Nephrol Dial Transplant 2008, 23(2):680-686.
42. Viasus D., Garcia-Vidal C., Cruzado J.M., et al. Epidemiology, clinical features and outcomes of pneumonia in patients with chronic kidney disease. Nephrol Dial Transplant 2011, 26(9):2899-2906.
43. Kawasaki S., Aoki N., Kikuchi H., et al. Clinical and microbiological evaluation of hemodialysis-associated pneumonia (HDAP): should HDAP be included in healthcare-associated pneumonia?. J Infect Chemother 2011, 17(5):640-645.
44. Hsu J.L., Siroka A.M., Smith M.W., et al. One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System. Int J Infect Dis 2011, 15(6):e382-e387.
45. Crothers K., Huang L., Goulet J.L., et al. HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era. Am J Respir Crit Care Med 2011, 183(3):388-395.
46. Franzetti F., Grassini A., Piazza M., et al. Nosocomial bacterial pneumonia in HIV-infected patients: risk factors for adverse outcome and implications for rational empiric antibiotic therapy. Infection 2006, 34(1):9-16.
47. Kang C.I., Song J.H., Ko K.S., et al. Clinical features and outcomes of Staphylococcus aureus infections in non-neutropenic cancer patients. Support Care Cancer 2012, 20(3):483-488.
48. Lam A.P., Wunderink R.G. The role of MRSA in healthcare-associated pneumonia. Semin Respir Crit Care Med 2009, 30(1):52-60.
49. Shorr A.F., Zilberberg M.D., Micek S.T., et al. Prediction of infection due to antibiotic-resistant bacteria by select risk factors for health care-associated pneumonia. Arch Intern Med 2008, 168(20):2205-2210.
50. Shorr A.F., Zilberberg M.D., Reichley R., et al. Validation of a clinical score for assessing the risk of resistant pathogens in patients with pneumonia presenting to the emergency department. Clin Infect Dis 2012, 54(2):193-198.
51. Lescure F.X., Locher G., Eveillard M., et al. Community-acquired infection with healthcare-associated methicillin-resistant Staphylococcus aureus: the role of home nursing care. Infect Control Hosp Epidemiol 2006, 27(11):1213-1218.
52. Micek S.T., Kollef K.E., Reichley R.M., et al. Health care-associated pneumonia and community-acquired pneumonia: a single-center experience. Antimicrob Agents Chemother 2007, 51(10):3568-3573.
53. Grenier C., Pepin J., Nault V., et al. Impact of guideline-consistent therapy on outcome of patients with healthcare-associated and community-acquired pneumonia. J Antimicrob Chemother 2011, 66(7):1617-1624.