Silk proteins stimulate osteoblast differentiation by suppressing the Notch signaling pathway in mesenchymal stem cells

Nutrition Research

Volumn 33, Issue 2, 2013, Pages 162-170

  Jung, So Ra ^a   Song, No Joon ^a   Yang, Dong Kwon ^b   Cho, Yong Jun ^c   Kim, Byung Joon ^d   Hong, Joung Woo ^e   Yun, Ui Jeong ^a   Jo, Dong Gyu ^a   Lee, Young Min ^f   Choi, Soo Young ^c   Park, Kye Won ^a  

^a Sungkyunkwan University   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

^c Hallym University   (South Korea)

^d Konyang University   (South Korea)

^e Kyung Hee University   (South Korea)

^f National Institute of Animal Science   (South Korea)

Author keywords

Bone; Multipotent cells; Notch; Osteoblast differentiation; Silk protein

Indexed keywords

ALKALINE PHOSPHATASE; MESSENGER RNA; NOTCH1 RECEPTOR; SILK FIBROIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2;

ALP GENE; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE REGENERATION; CELL DIFFERENTIATION; CELL ISOLATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE SILENCING; INTRACELLULAR SIGNALING; MESENCHYMAL STEM CELL; NONHUMAN; NUTRITIONAL VALUE; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; RUNX2 GENE;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROINS; FRACTURES, BONE; GENE EXPRESSION; MESENCHYMAL STROMAL CELLS; MICE; OSTEOBLASTS; OSTEOGENESIS; OSTEOPOROSIS; RATS; RECEPTOR, NOTCH1; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SILK;

MUS; RATTUS;

EID: 84873522773     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2012.11.006     Document Type: Article

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