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Volumn 42, Issue 1, 2010, Pages 12-20

Further understanding of fat biology: Lessons from a fat fly

Author keywords

Adipocytes; Adipogenesis; Adipose tissue; Cell differentiation; Drosophila; Models, biological; Obesity; PPAR

Indexed keywords

FAT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 76749087130     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2010.42.1.007     Document Type: Review
Times cited : (35)

References (58)
  • 2
    • 60449083172 scopus 로고    scopus 로고
    • The epicurean fly: Using Drosophila melanogaster to study metabolism
    • Bharucha KN. The epicurean fly: using Drosophila melanogaster to study metabolism. Pediatr Res 2009;65:132-7
    • (2009) Pediatr Res , vol.65 , pp. 132-137
    • Bharucha, K.N.1
  • 3
    • 0036696845 scopus 로고    scopus 로고
    • Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila
    • Bialecki M, Shilton A, Fichtenberg C, Segraves WA, Thummel CS. Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila. Dev Cell 2002;3:209-20
    • (2002) Dev Cell , vol.3 , pp. 209-220
    • Bialecki, M.1    Shilton, A.2    Fichtenberg, C.3    Segraves, W.A.4    Thummel, C.S.5
  • 4
    • 10644276290 scopus 로고    scopus 로고
    • Drosophila, the golden bug, emerges as a tool for human genetics
    • Bier E. Drosophila, the golden bug, emerges as a tool for human genetics. Nat Rev Genet 2005;6:9-23
    • (2005) Nat Rev Genet , vol.6 , pp. 9-23
    • Bier, E.1
  • 5
    • 36549005538 scopus 로고    scopus 로고
    • Caffrey DR, Dana PH, Mathur V, Ocano M, Hong EJ, Wang YE, Somaroo S, Caffrey BE, Potluri S, Huang ES. PFAAT version 2.0: a tool for editing, annotating, and analyzing multiple sequence alignments. BMC Bioinformatics 2007;8: 381
    • Caffrey DR, Dana PH, Mathur V, Ocano M, Hong EJ, Wang YE, Somaroo S, Caffrey BE, Potluri S, Huang ES. PFAAT version 2.0: a tool for editing, annotating, and analyzing multiple sequence alignments. BMC Bioinformatics 2007;8: 381
  • 6
    • 0034639940 scopus 로고    scopus 로고
    • A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes
    • Culetto E, Sattelle DB. A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes. Hum Mol Genet 2000;9:869-77
    • (2000) Hum Mol Genet , vol.9 , pp. 869-877
    • Culetto, E.1    Sattelle, D.B.2
  • 7
    • 0013415751 scopus 로고
    • Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. I. Adult morphology, longevity, egg production, and egg lethality
    • Doane WW. Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. I. Adult morphology, longevity, egg production, and egg lethality. J Exp Zool 1960;145:1-21
    • (1960) J Exp Zool , vol.145 , pp. 1-21
    • Doane, W.W.1
  • 8
    • 84981878807 scopus 로고
    • Amylase variants in Drosophila melanogaster: Linkage studies and characterization of enzyme extracts
    • Doane WW. Amylase variants in Drosophila melanogaster: linkage studies and characterization of enzyme extracts. J Exp Zool 1969;171:31-41
    • (1969) J Exp Zool , vol.171 , pp. 31-41
    • Doane, W.W.1
  • 9
    • 44149120984 scopus 로고    scopus 로고
    • Molecular determinants of brown adipocyte formation and function
    • Farmer SR. Molecular determinants of brown adipocyte formation and function. Genes Dev 2008;22:1269-75
    • (2008) Genes Dev , vol.22 , pp. 1269-1275
    • Farmer, S.R.1
  • 10
    • 67949102053 scopus 로고    scopus 로고
    • Recent progress in the biology and physiology of sirtuins
    • Finkel T, Deng CX, Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009;460:587-91
    • (2009) Nature , vol.460 , pp. 587-591
    • Finkel, T.1    Deng, C.X.2    Mostoslavsky, R.3
  • 13
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 1995;83:803-12
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 14
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998;395:763-70
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 15
    • 69149110896 scopus 로고    scopus 로고
    • Remote control of insulin secretion by fat cells in Drosophila
    • Geminard C, Rulifson EJ, Leopold P. Remote control of insulin secretion by fat cells in Drosophila. Cell Metab 2009;10:199-207
    • (2009) Cell Metab , vol.10 , pp. 199-207
    • Geminard, C.1    Rulifson, E.J.2    Leopold, P.3
  • 16
    • 0016178461 scopus 로고
    • An established pre-adipose cell line and its differentiation in culture
    • Green H, Meuth M. An established pre-adipose cell line and its differentiation in culture. Cell 1974;3:127-33
    • (1974) Cell , vol.3 , pp. 127-133
    • Green, H.1    Meuth, M.2
  • 17
    • 0017239088 scopus 로고
    • Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells
    • Green H, Kehinde O. Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell 1976;7:105-13
    • (1976) Cell , vol.7 , pp. 105-113
    • Green, H.1    Kehinde, O.2
  • 19
    • 13844262924 scopus 로고    scopus 로고
    • Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes
    • Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA. Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev 2005;19:453-61
    • (2005) Genes Dev , vol.19 , pp. 453-461
    • Guan, H.P.1    Ishizuka, T.2    Chui, P.C.3    Lehrke, M.4    Lazar, M.A.5
  • 21
    • 59149105634 scopus 로고    scopus 로고
    • A supersized list of obesity genes
    • Hofker M, Wijmenga C. A supersized list of obesity genes. Nat Genet 2009;41:139-40
    • (2009) Nat Genet , vol.41 , pp. 139-140
    • Hofker, M.1    Wijmenga, C.2
  • 22
    • 15944408369 scopus 로고    scopus 로고
    • Nuclear receptors - a perspective from Drosophila
    • King-Jones K, Thummel CS. Nuclear receptors - a perspective from Drosophila. Nat Rev Genet 2005;6:311-23
    • (2005) Nat Rev Genet , vol.6 , pp. 311-323
    • King-Jones, K.1    Thummel, C.S.2
  • 24
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman PG. Obesity as a medical problem. Nature 2000;404:635-43
    • (2000) Nature , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 25
    • 0033846989 scopus 로고    scopus 로고
    • Steroid regulation of postembryonic development and reproduction in Drosophila
    • Kozlova T, Thummel CS. Steroid regulation of postembryonic development and reproduction in Drosophila. Trends Endocrinol Metab 2000;11:276-80
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 276-280
    • Kozlova, T.1    Thummel, C.S.2
  • 28
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 1995;270: 12953-6
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 30
    • 67749119974 scopus 로고    scopus 로고
    • Marvin KA, Reinking JL, Lee AJ, Pardee K, Krause HM, Burstyn JN. Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO. Biochemistry 2009;48:7056-71
    • Marvin KA, Reinking JL, Lee AJ, Pardee K, Krause HM, Burstyn JN. Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO. Biochemistry 2009;48:7056-71
  • 32
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 1994;331:1188-93
    • (1994) N Engl J Med , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3    Joyce, M.4    Olefsky, J.5
  • 33
    • 0025091575 scopus 로고
    • Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor
    • Oro AE, Mckeown M, Evans RM. Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor. Nature 1990;347:298-301
    • (1990) Nature , vol.347 , pp. 298-301
    • Oro, A.E.1    Mckeown, M.2    Evans, R.M.3
  • 35
    • 56449105671 scopus 로고    scopus 로고
    • Before they were fat: Adipocyte progenitors
    • Park KW, Halperin DS, Tontonoz P. Before they were fat: adipocyte progenitors. Cell Metab 2008;8:54-7
    • (2008) Cell Metab , vol.8 , pp. 54-57
    • Park, K.W.1    Halperin, D.S.2    Tontonoz, P.3
  • 36
    • 0035479747 scopus 로고    scopus 로고
    • A family of proteins related to Spatzle, the toll receptor ligand, are encoded in the Drosophila genome
    • Parker JS, Mizuguchi K, Gay NJ. A family of proteins related to Spatzle, the toll receptor ligand, are encoded in the Drosophila genome. Proteins 2001;45:71-80
    • (2001) Proteins , vol.45 , pp. 71-80
    • Parker, J.S.1    Mizuguchi, K.2    Gay, N.J.3
  • 40
    • 33746607619 scopus 로고    scopus 로고
    • Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U.S
    • Schulz LO, Bennett PH, Ravussin E, Kidd JR, Kidd KK, Esparza J, Valencia ME. Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U.S. Diabetes Care 2006;29:1866-71
    • (2006) Diabetes Care , vol.29 , pp. 1866-1871
    • Schulz, L.O.1    Bennett, P.H.2    Ravussin, E.3    Kidd, J.R.4    Kidd, K.K.5    Esparza, J.6    Valencia, M.E.7
  • 42
    • 0025124572 scopus 로고
    • The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily
    • Segraves WA, Hogness DS. The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily. Genes Dev 1990;4:204-19
    • (1990) Genes Dev , vol.4 , pp. 204-219
    • Segraves, W.A.1    Hogness, D.S.2
  • 43
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman BM, Flier JS. Obesity and the regulation of energy balance. Cell 2001;104:531-43
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 45
    • 0031435337 scopus 로고    scopus 로고
    • Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene
    • Tanaka T, Yoshida N, Kishimoto T, Akira S. Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J 1997;16:7432-43
    • (1997) EMBO J , vol.16 , pp. 7432-7443
    • Tanaka, T.1    Yoshida, N.2    Kishimoto, T.3    Akira, S.4
  • 47
    • 0027340093 scopus 로고
    • Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle
    • Thomas HE, Stunnenberg HG, Stewart AF. Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle. Nature 1993;362:471-5
    • (1993) Nature , vol.362 , pp. 471-475
    • Thomas, H.E.1    Stunnenberg, H.G.2    Stewart, A.F.3
  • 48
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARgamma
    • Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem 2008;77: 289-312
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 49
    • 0024337858 scopus 로고
    • Determinants of target gene specificity for steroid/thyroid hormone receptors
    • Umesono K, Evans RM. Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell 1989;57:1139-46
    • (1989) Cell , vol.57 , pp. 1139-1146
    • Umesono, K.1    Evans, R.M.2
  • 51
    • 0031930804 scopus 로고    scopus 로고
    • Dietary fat, genetic predisposition, and obesity: Lessons from animal models
    • West DB, York B. Dietary fat, genetic predisposition, and obesity: lessons from animal models. Am J Clin Nutr 1998;67:505S-512S
    • (1998) Am J Clin Nutr , vol.67
    • West, D.B.1    York, B.2
  • 53
    • 0028971225 scopus 로고
    • Conditional ectopic expression of C/EBP beta in NIH-3T3 cells induces PPAR gamma and stimulates adipogenesis
    • Wu Z, Xie Y, Bucher NL, Farmer SR. Conditional ectopic expression of C/EBP beta in NIH-3T3 cells induces PPAR gamma and stimulates adipogenesis. Genes Dev 1995;9: 2350-63
    • (1995) Genes Dev , vol.9 , pp. 2350-2363
    • Wu, Z.1    Xie, Y.2    Bucher, N.L.3    Farmer, S.R.4
  • 54
    • 0026646635 scopus 로고
    • Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation
    • Yao TP, Segraves WA, Oro AE, Mckeown M, Evans RM. Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell 1992;71:63-72
    • (1992) Cell , vol.71 , pp. 63-72
    • Yao, T.P.1    Segraves, W.A.2    Oro, A.E.3    Mckeown, M.4    Evans, R.M.5
  • 55
    • 0030239728 scopus 로고    scopus 로고
    • Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross
    • York B, Lei K, West DB. Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross. Mamm Genome 1996;7:677-81
    • (1996) Mamm Genome , vol.7 , pp. 677-681
    • York, B.1    Lei, K.2    West, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.