Insulin and IGF1 Receptors Are Essential for XX and XY Gonadal Differentiation and Adrenal Development in Mice

PLoS Genetics

Volumn 9, Issue 1, 2013, Pages

  Pitetti, Jean Luc ^a   Calvel, Pierre ^a   Romero, Yannick ^a   Conne, Béatrice ^a   Truong, Vy ^b   Papaioannou, Marilena D ^a   Schaad, Olivier ^c   Docquier, Mylène ^c   Herrera, Pedro Luis ^a   Wilhelm, Dagmar ^b,d   Nef, Serge ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; SOMATOMEDIN; SOMATOMEDIN C RECEPTOR; TESTIS DETERMINING FACTOR;

ADRENAL CORTEX; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GONAD DEVELOPMENT; KARYOTYPE 46,XX; KARYOTYPE 46,XY; MALE; MOUSE; NONHUMAN; OVARY DEVELOPMENT; RECEPTOR UPREGULATION; REPRODUCTION; SEX DETERMINATION; SIGNAL TRANSDUCTION; SOMATIC CELL; STEM CELL; TESTIS DEVELOPMENT;

ADRENAL CORTEX; ADRENAL GLANDS; ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; DISORDERS OF SEX DEVELOPMENT; FEMALE; GONADS; HUMANS; INSULIN; MALE; MICE; OVARY; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SEX CHROMOSOMES; SEX DETERMINATION PROCESSES; SIGNAL TRANSDUCTION; TESTIS;

EID: 84873519033     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003160     Document Type: Article

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