Exercise promotes bone marrow cell survival and recipient reconstitution post-bone marrow transplantation, which is associated with increased survival

Experimental Hematology

Volumn 41, Issue 2, 2013, Pages 143-154

  De Lisio, Michael ^a   Baker, Jeff M ^a   Parise, Gianni ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 7; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL HOMING; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXERCISE; FEMALE; FLOW CYTOMETRY; GRAFT SURVIVAL; LEUKOCYTE COUNT; MALE; MEMBRANE RECONSTITUTION; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEDENTARY LIFESTYLE; TREADMILL EXERCISE;

ANIMALS; APOPTOSIS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; FEMALE; GENES, REPORTER; GRAFT SURVIVAL; GREEN FLUORESCENT PROTEINS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; PHYSICAL CONDITIONING, ANIMAL; RADIATION CHIMERA; RADIATION INJURIES, EXPERIMENTAL; RUNNING; SEDENTARY LIFESTYLE;

EID: 84873503379     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2012.10.003     Document Type: Article

References (49)

1. Tomblyn M.B., Arora M., Baker K.S., et al. Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: analysis of graft sources and long-term outcome. J Clin Oncol 2009, 27:3634-3641.
2. Copelan E.A. Hematopoietic stem-cell transplantation. N Engl J Med 2006, 354:1813-1826.
3. Amsel S., Dell E.S. Response of the preosteoblast and stem cell of rat bone marrow to a lethal dose of X-irradiation or cyclophosphamide. Cell Proliferation 1971, 4:255-261.
4. Lange C., Brunswig-Spickenheier B., Cappallo-Obermann H., et al. Radiation rescue: mesenchymal stromal cells protect from lethal irradiation. PLoS ONE 2011, 6:e14486.
5. Nelson J.C. Accidental or intentional exposure to ionizing radiation: biodosimetry and treatment options. Exp Hematol 2007, 35:24-27.
6. Hayashi T., Morishita Y., Kubo Y., et al. Long-term effects of radiation dose on inflammatory markers in atomic bomb survivors. Am J Med 2005, 118:83-86.
7. Li X.-M., Hu Z., Jorgenson M.L., et al. Bone marrow sinusoidal endothelial cells undergo nonapoptotic cell death and are replaced by proliferating sinusoidal cells in situ to maintain the vascular niche following lethal irradiation. Exp Hematol 2008, 36:1143-1156.
8. Salter A.B., Meadows S.K., Muramoto G.G., et al. Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo. Blood 2009, 113:2104-2107.
9. Slayton W.B., Li X., Butler J., et al. The role of the donor in the repair of the marrow vascular niche following hematopoietic stem cell transplant. Stem Cells 2007, 25:2945-2955.
10. Czechowicz A., Kraft D., Weissman I.L., Bhattacharya D. Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science 2007, 318:1296-1299.
11. Kang Y., Chen B.J., DeOliveira D., Mito J., Chao N.J. Selective enhancement of donor hematopoietic cell engraftment by the CXCR4 antagonist AMD3100 in a mouse transplantation model. PLoS ONE 2010, 5:e11316.
12. Dominici M., Rasini V., Bussolari R., et al. Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation. Blood 2009, 114:2333-2343.
13. Garrett R.W., Emerson S.G. Bone and blood vessels: the hard and the soft of hematopoietic stem cell niches. Cell Stem Cell 2009, 4:503-506.
14. Pulsipher M.A., Chitphakdithai P., Logan B.R., et al. Donor, recipient, and transplant characteristics as risk factors after unrelated donor PBSC transplantation: beneficial effects of higher CD34+ cell dose. Blood 2009, 114:2606-2616.
15. Calvi L.M., Adams G.B., Weibrecht K.W., et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003, 425:841-846.
16. Adams G.B., Martin R.P., Alley I.R., et al. Therapeutic targeting of a stem cell niche. Nat Biotech 2007, 25:238-243.
17. Zsebo K.M., Smith K.A., Hartley C.A., et al. Radioprotection of mice by recombinant rat stem cell factor. Proc Nat Acad Sci USA 1992, 89:9464-9468.
18. Hérodin F., Bourin P., Mayol J.-F., Lataillade J.-J., Drouet M. Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival. Blood 2003, 101:2609-2616.
19. Kim S.-D., Kim H- S. A series of bed exercises to improve lymphocyte count in allogeneic bone marrow transplantation patients. Eur J Cancer Care (Engl) 2006, 15:453-457.
20. Dimeo F., Fetscher S., Lange W., Mertelsmann R., Keul J. Effects of aerobic exercise on the physical performance and incidence of treatment-related complications after high-dose chemotherapy. Blood 1997, 90:3390-3394.
21. Chamorro-Viña C., Ruiz J.R., Santana-Sosa E., et al. Exercise during hematopoietic stem cell transplant hospitalization in children. Med Sci Sports Exerc 2010, 42:1045-1053.
22. Hayes S.C., Rowbottom D., Davies P.S.W., Parker T.W., Bashford J. Immunological changes after cancer treatment and participation in an exercise program. Med Sci Sports Exerc 2003, 35:2-9.
23. De Lisio M., Phan N., Boreham D.R., Parise G. Exercise-induced protection of bone marrow cells following exposure to radiation. Appl Physiol Nutr Metab 2011, 36:80-87.
24. Baker J.M., De Lisio M., Parise G. Endurance exercise training promotes medullary hematopoiesis. FASEB J 2011, 25:4348-4357.
25. De Lisio M., Parise G. Characterization of the effects of exercise training on hematopoietic stem cell quantity and function. J Appl Physiol 2012, Sep 27 [Epub ahead of print].
26. Okabe M. 'Green mice' as a source of ubiquitous green cells. FEBS Lett 1997, 407:313-319.
27. Covey S.D., Krieger M., Wang W., Penman M., Trigatti B.L. Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells. Arterioscler Thromb Vasc Biol 2003, 23:1589-1594.
28. Challen G.A., Boles N., Lin K.-Y.K., Goodell M.A. Mouse hematopoietic stem cell identification and analysis. Cytometry Part A 2009, 75A:14-24.
29. Saikumar P., Dong Z., Mikhailov V., et al. Apoptosis: definition, mechanisms, and relevance to disease. Am J Med 1999, 107:489-506.
30. Wiskemann J., Huber G. Physical exercise as adjuvant therapy for patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant 2008, 41:321-329.
31. Dumont F., Roux A.L., Bischoff P. Radiation countermeasure agents: an update. Expert Opin Ther Pat 2010, 20:73-101.
32. Petersen A.M.W., Pedersen B.K. The anti-inflammatory effect of exercise. J Appl Physiol 2005, 98:1154-1162.
33. Walsh N.P., Gleeson M., Shephard R.J., et al. Position statement. Part one: immune function and exercise. Exerc Immunol Rev 2011, 17:6-63.
34. Reed J.L., De Souza M.J., Williams N.I. Effects of exercise combined with caloric restriction on inflammatory cytokines. Appl Physiol Nutr Metab 2010, 35:573-582.
35. Lira F.S., Koyama C.H., Yamashita A.S., et al. Chronic exercise decreases cytokine production in healthy rat skeletal muscle. Cell Biochem Funct 2009, 27:458-461.
36. Liu Y., Wang L., Kikuiri T., et al. Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α. Nat Med 2011, 17:1594-1601.
37. Bonsignore M.R., Morici G., Santoro A., et al. Circulating hematopoietic progenitor cells in runners. J Appl Physiol 2002, 93:1691-1697.
38. Morgado J. Cytokine production by monocytes, neutrophils, and dendritic cells is hampered by long-term intensive training in elite swimmers. Eur J Appl Physiol 2012, 112:471-482.
39. Amir O., Rogowski O., David M., et al. Circulating interleukin-10: association with higher mortality in systolic heart failure patients with elevated tumor necrosis factor-alpha. Isr Med Assoc J 2010, 12:158-162.
40. Chen T., Burke K.A., Zhan Y., et al. IL-12 facilitates both the recovery of endogenous hematopoiesis and the engraftment of stem cells after ionizing radiation. Exp Hematol 2007, 35:203-213.
41. Dainiak N. Hematologic consequences of exposure to ionizing radiation. Exp Hematol 2002, 30:513-528.
42. Naveiras O., Nardi V., Wenzel P.L., et al. Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature 2009, 460:259-263.
43. Corre J., Barreau C., Cousin B., et al. Human subcutaneous adipose cells support complete differentiation but not self-renewal of hematopoietic progenitors. J Cell Physiol 2006, 208:282-288.
44. Hooper A.T., Butler J.M., Nolan D.J., et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell 2009, 4:263-274.
45. Kopp H.-G., Avecilla S.T., Hooper A.T., Rafii S. The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology 2005, 20:349-356.
46. Lepperdinger G. Inflammation and mesenchymal stem cell aging. Curr Opin Immunol 2011, 23:518-524.
47. Deans R.J., Moseley A.B. Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 2000, 28:875-884.
48. Haylock D.N., Williams B., Johnston H.M., et al. Hemopoietic stem cells with higher hemopoietic potential reside at the bone marrow endosteum. Stem Cells 2007, 25:1062-1069.
49. Wilson A., Trumpp A. Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol 2006, 6:93-106.