Intravenous Delivery of HIV-Based Lentiviral Vectors Preferentially Transduces F4/80+ and Ly-6C+ Cells in Spleen, Important Target Cells in Autoimmune Arthritis

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  van den Brand, Ben T ^a   Vermeij, Eline A ^a   Waterborg, Claire E J ^a   Arntz, Onno J ^a   Kracht, Michael ^b   Bennink, Miranda B ^a   van den Berg, Wim B ^a   van de Loo, Fons A J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 6; LENTIVIRUS VECTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE ARTHRITIS; AUTOIMMUNE DISEASE; BONE EROSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; FLOW CYTOMETRY; GENE; GENE TARGETING; GENETIC TRANSDUCTION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; T LYMPHOCYTE SUBPOPULATION; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 GENE; VIRAL GENE THERAPY;

ANIMALS; ANTIGENS, DIFFERENTIATION; ANTIGENS, LY; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNITY; COLLAGEN TYPE II; CYTOKINES; DENDRITIC CELLS; GENE EXPRESSION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HIV; INJECTIONS, INTRAVENOUS; MALE; MAP KINASE KINASE KINASES; MICE; MICE, INBRED DBA; SPLEEN; SYNOVIAL FLUID; T-LYMPHOCYTE SUBSETS; TRANSDUCTION, GENETIC; TRANSGENES;

EID: 84873493119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055356     Document Type: Article

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