Differential gene expression profiling between genotoxic and non-genotoxic hepatocarcinogens in young rat liver determined by quantitative real-time PCR and principal component analysis

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 751, Issue 1, 2013, Pages 73-83

  Suenaga, Kazuya ^a   Takasawa, Hironao ^b   Watanabe, Takashi ^a   Wako, Yumi ^b   Suzuki, Takayoshi ^c   Hamada, Shuichi ^b   Furihata, Chie ^a,c  

^a AOYAMA GAKUIN UNIVERSITY   (Japan)

^b LSI MEDIENCE CORPORATION   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Gene expression; Gene network; PCA; Quantitative real time PCR; Rat liver

Indexed keywords

2,6 DINITROTOLUENE; CARCINOGEN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN G1; CYSTEINE RICH PROTEIN 61; CYTOCHROME P450 4A1; DIETHYLNITROSAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPOXIDE HYDROLASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH DIFFERENTIATION FACTOR 15; HEAT SHOCK PROTEIN 27; HEME OXYGENASE 1; MYC PROTEIN; PHENACETIN; PHOSPHOMANNOMUTASE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; POLO LIKE KINASE 2; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN BAX; PROTEIN C JUN; PROTEIN P53; SOMATOMEDIN BINDING PROTEIN 1; TUBULIN; TUMOR NECROSIS FACTOR;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE; GENE EXPRESSION PROFILING; GENOTOXICITY; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MARKER GENE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; OXIDATIVE STRESS; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOGENS; GENE EXPRESSION PROFILING; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICROARRAY ANALYSIS; MUTAGENS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION;

RATTUS;

EID: 84873474569     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.11.003     Document Type: Article

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