Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats

Journal of Applied Physiology

Volumn 114, Issue 3, 2013, Pages 402-410

  Huang, Yao Te ^a   Yao, Chun Hsu ^a   Way, Chia Li ^a   Lee, Kung Wei ^b   Tsai, Cheng Yen ^c   Ou, Hsiu Chung ^a   Kuo, Wei Wen ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Diabetic cardiomyopathy; Echocardiography; Garlic; PI3k Akt

Indexed keywords

3 NITROTYROSINE; 3-NITROTYROSINE; ALLYL COMPOUND; ALLYL SULFIDE; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; DEATH RECEPTOR; DIALLYL DISULFIDE; DIALLYL TRISULFIDE; DISULFIDE; DRUG DERIVATIVE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; SULFIDE; SUPEROXIDE DISMUTASE; TYROSINE;

ANIMAL; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CELL SURVIVAL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GARLIC; HEART; MALE; METABOLISM; MITOCHONDRION; PATHOLOGY; RAT; SIGNAL TRANSDUCTION; WISTAR RAT;

ALLYL COMPOUNDS; ANIMALS; APOPTOSIS; CARDIOMYOPATHIES; CASPASE 3; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DISULFIDES; GARLIC; HEART; MALE; MITOCHONDRIA; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, WISTAR; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; SULFIDES; SUPEROXIDE DISMUTASE; TYROSINE;

EID: 84873472725     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00672.2012     Document Type: Article

References (41)

1. Asghar O, Al-Sunni A, Khavandi K, Khavandi A, Withers S, Greenstein A, Heagerty AM, Malik RA. Diabetic cardiomyopathy. Clin Sci (Lond) 116: 741-760, 2009.
2. Banerjee SK, Mukherjee PK, Maulik SK. Garlic as an antioxidant: the good, the bad and the ugly. Phytother Res 17: 97-106, 2003.
3. Baskar R, Bian J. Hydrogen sulfide gas has cell growth regulatory role. Eur J Pharmacol 656: 5-9, 2011.
4. Benavides GA, Squadrito GL, Mills RW, Patel HD, Isbell TS, Patel RP, Darley-Usmar VM, Doeller JE, Kraus DW. Hydrogen sulfide mediates the vasoactivity of garlic. Proc Natl Acad Sci USA 104: 17977- 17982, 2007.
5. Benhar M, Forrester MT, Stamler JS. Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol 10: 721-732, 2009.
6. Benhar M, Stamler JS. A central role for S-nitrosylation in apoptosis. Nat Cell Biol 7: 645-646, 2005.
7. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
8. Butt MS, Sultan MT, Iqbal J. Garlic: nature's protection against physiological threats. Crit Rev Food Sci Nutr 49: 538-551, 2009.
9. Calvert JW, Coetzee WA, Lefer DJ. Novel insights into hydrogen sulfide-mediated cytoprotection. Antioxid Redox Signal 12: 1203-1217, 2010.
10. Calvert JW, Jha S, Gundewar S, Elrod JW, Ramachandran A, Pattillo CB, Kevil CG, Lefer DJ. Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circ Res 105: 365-374, 2009.
11. Chang SH, Liu CJ, Kuo CH, Chen H, Lin WY, Teng KY, Chang SW, Tsai CH, Tsai FJ, Huang CY, Tzang BS, Kuo WW. Garlic oil alleviates MAPKs- and IL-6-mediated diabetes-related cardiac hypertrophy in STZinduced DM rats. Evid Based Complement Alternat Med 2011: 950150, 2011.
12. Fayssoil A. Tissue Doppler characterization of cardiac phenotype in mouse. Eur J Radiol 72: 82-84, 2009.
13. Fisher CD, Augustine LM, Maher JM, Nelson DM, Slitt AL, Klaassen CD, Lehman-McKeeman LD, Cherrington NJ. Induction of drugmetabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug Metab Dispos 35: 995-1000, 2007.
14. Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 114: 597-605, 2006.
15. Grundy SM, Howard B, Smith S Jr, Eckel R, Redberg R, Bonow RO. Prevention Conference VI: Diabetes and Cardiovascular Disease: executive summary: conference proceeding for healthcare professionals from a special writing group of the American Heart Association. Circulation 105: 2231-2239, 2002.
16. Hu FB. Globalization of diabetes: the role of diet, lifestyle, and genes. Diabetes Care 34: 1249-1257, 2011.
17. Iciek M, Kwiecien I, Wlodek L. Biological properties of garlic and garlic-derived organosulfur compounds. Environ Mol Mutagen 50: 247- 265, 2009.
18. Joffe II, Travers KE, Perreault-Micale CL, Hampton T, Katz SE, Morgan JP, Douglas PS. Abnormal cardiac function in the streptozotocin- induced non-insulin-dependent diabetic rat: noninvasive assessment with Doppler echocardiography and contribution of the nitric oxide pathway. J Am Coll Cardiol 34: 2111-2119, 1999.
19. Khullar M, Al-Shudiefat AA, Ludke A, Binepal G, Singal PK. Oxidative stress: a key contributor to diabetic cardiomyopathy. Can J Physiol Pharmacol 88: 233-240, 2010.
20. Kimura Y, Goto Y, Kimura H. Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxid Redox Signal 12: 1-13, 2010.
21. Kuo WW, Liu CJ, Chen LM, Wu CH, Chu CH, Liu JY, Lu MC, Lin JA, Lee SD, Huang CY. Cardiomyoblast apoptosis induced by insulinlike growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II. Apoptosis 11: 1075-1089, 2006.
22. Lanneau D, Brunet M, Frisan E, Solary E, Fontenay M, Garrido C. Heat shock proteins: essential proteins for apoptosis regulation. J Cell Mol Med 12: 743-761, 2008.
23. Li L, Rose P, Moore PK. Hydrogen sulfide and cell signaling. Annu Rev Pharmacol Toxicol 51: 169-187, 2011.
24. Munday R, Munday JS, Munday CM. Comparative effects of mono-, di-, tri-, and tetrasulfides derived from plants of the Allium family: redox cycling in vitro and hemolytic activity and Phase 2 enzyme induction in vivo. Free Radic Biol Med 34: 1200-1211, 2003.
25. Mustafa AK, Gadalla MM, Sen N, Kim S, Mu W, Gazi SK, Barrow RK, Yang G, Wang R, Snyder SH. H2S signals through protein Ssulfhydration. Sci Signal 2: ra72, 2009.
26. Ou HC, Tzang BS, Chang MH, Liu CT, Liu HW, Lii CK, Bau DT, Chao PM, Kuo WW. Cardiac contractile dysfunction and apoptosis in streptozotocin-induced diabetic rats are ameliorated by garlic oil supplementation. J Agric Food Chem 58: 10347-10355, 2010.
27. Pitocco D, Zaccardi F, Di Stasio E, Romitelli F, Santini SA, Zuppi C, Ghirlanda G. Oxidative stress, nitric oxide, diabetes. Rev Diabet Stud 7: 15-25, 2010.
28. Rahman K, Lowe GM. Garlic and cardiovascular disease: a critical review. J Nutr 136: 736S-740S, 2006.
29. Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jaattela M, Penninger JM, Garrido C, Kroemer G. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 3: 839-843, 2001.
30. Rinaldi L, Gobbi G, Pambianco M, Micheloni C, Mirandola P, Vitale M. Hydrogen sulfide prevents apoptosis of human PMN via inhibition of p38 and caspase 3. Lab Invest 86: 391-397, 2006.
31. Rubler S, Dlugash J, Yuceoglu YZ, Kumral T, Branwood AW, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol 30: 595-602, 1972.
32. Sen N, Paul BD, Gadalla MM, Mustafa AK, Sen T, Xu R, Kim S, Snyder SH. Hydrogen sulfide-linked sulfhydration of NF-kappaB mediates its antiapoptotic actions. Mol Cell 45: 13-24, 2012.
33. Shan YX, Yang TL, Mestril R, Wang PH. Hsp10 and Hsp60 suppress ubiquitination of insulin-like growth factor-1 receptor and augment insulin- like growth factor-1 receptor signaling in cardiac muscle: implications on decreased myocardial protection in diabetic cardiomyopathy. J Biol Chem 278: 45492-45498, 2003.
34. Vassort G, Turan B. Protective role of antioxidants in diabetes-induced cardiac dysfunction. Cardiovasc Toxicol 10: 73-86, 2010.
35. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053, 2004.
36. Winer N, Sowers Jr. Epidemiology of diabetes. J Clin Pharmacol 44: 397-405, 2004.
37. Wu CC, Sheen LY, Chen HW, Kuo WW, Tsai SJ, Lii CK. Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats. J Agric Food Chem 50: 378-383, 2002.
38. Yang Z, Yang C, Xiao L, Liao X, Lan A, Wang X, Guo R, Chen P, Hu C, Feng J. Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia-induced injury in H9c2 cardiac myocytes. Int J Mol Med 28: 397-403, 2011.
39. Yong QC, Lee SW, Foo CS, Neo KL, Chen X, Bian JS. Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning. Am J Physiol Heart Circ Physiol 295: H1330-H1340, 2008.
40. Zhang P, Zhang X, Brown J, Vistisen D, Sicree R, Shaw J, Nichols G. Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes Res Clin Pract 87: 293-301, 2010.
41. Zhu H, Itoh K, Yamamoto M, Zweier JL, Li Y. Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury. FEBS Lett 579: 3029-3036, 2005.