Cardioprotective effect of δ-opioid receptor agonist vs mild therapeutic hypothermia in a rat model of cardiac arrest with extracorporeal life support

Resuscitation

Volumn 84, Issue 2, 2013, Pages 244-248

  Rungatscher, Alessio ^a   Linardi, Daniele ^a   Giacomazzi, Alice ^a   Tessari, Maddalena ^a   Menon, Tiziano ^a   Mazzucco, Alessandro ^a   Faggian, Giuseppe ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Akt; Delta opioid receptor; ERK; Extracorporeal life support; Hypothermia; Myocardial function

Indexed keywords

DELTA OPIATE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; LACTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; COMPARATIVE STUDY; CONTROLLED STUDY; COOLING; DRUG EFFICACY; ENZYME PHOSPHORYLATION; EXTRACORPOREAL CIRCULATION; HEART ARREST; HEART CONDUCTION; HEART FUNCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE BIOPSY; HEART PROTECTION; HEART VENTRICLE FIBRILLATION; INDUCED HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESUSCITATION; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME;

ADVANCED CARDIAC LIFE SUPPORT; ANIMALS; ENKEPHALIN, LEUCINE-2-ALANINE; HEART ARREST; HYPOTHERMIA, INDUCED; MALE; RATS; RATS, WISTAR; RECEPTORS, OPIOID, DELTA;

EID: 84873472364     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2012.06.016     Document Type: Article

References (30)

1. Mongardon N., Dumas F., Ricome S., et al. Postcardiac arrest syndrome: from immediate resuscitation to long-term outcome. Ann Intensive Care 2011, 1:45.
2. Nichol G., Karmy-Jones R., Salerno C., Cantore L., Becker L. Systematic review of percutaneous cardiopulmonary bypass for cardiac arrest or cardiogenic shock states. Resuscitation 2006, 70:381-394.
3. Deakin C.D., Nolan J.P., Soar J., et al. European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support. Resuscitation 2010, 81:1305-1352.
4. Polderman K.H. Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med 2009, 37:S186-S202.
5. Lahorra J.A., Torchiana D.F., Tolis G., et al. Rapid cooling contracture with cool cardioplegia. Ann Thorac Surg 1987, 44:467-470.
6. Karck M., Tanaka S., Bolling S.F., et al. Myocardial protection by ischemic preconditioning and δ-opioid receptor activation in the isolated working rat heart. J Thorac Cardiovasc Surg 2001, 122:986-992.
7. Kevelaitis E., Peynet J., Mouas C., Launay J.M., Menasché P. Opening of potassium channel: the common cardioprotective link between preconditioning and natural hibernation?. Circulation 1999, 99:3079-3085.
8. Cohen M.V., Philipp S., Krieg T., et al. Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways. J Mol Cell Cardiol 2007, 42:842-851.
9. Förster K., Kuno A., Solenkova N., Felix S.B., Krieg T. The delta-opioid receptor agonist DADLE at reperfusion protects the heart through activation of pro-survival kinases via EGF receptor transactivation. Am J Physiol Heart Circ Physiol 2007, 293:1604-1608.
10. Cresce G.D., Walpoth B.H., Mugnai D., et al. Validation of a rat model of cardiopulmonary bypass with a new miniaturized hollow fiber oxygenator. ASAIO J 2008, 54:514-518.
11. Pacher P., Nagayama T., Mukhopadhyay P., Batkai S., Kass D.A. Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats. Nat Protoc 2008, 3:1422-1434.
12. Menegazzi J.J., Salcido D.D., Housler G.J., Logue E.S. Feasibility of initiating extracorporeal life support during mechanical chest compression CPR: a porcine pilot study. Resuscitation 2012, 83:130-133.
13. Poncelet A.J., van Steenberghe M., Moniotte S., et al. Cardiac and neurological assessment of normothermia/warm blood cardioplegia vs hypothermia/cold crystalloid cardioplegia in pediatric cardiac surgery: insight from a prospective randomized trial. Eur J Cardiothorac Surg 2011, 40:1384-1390.
14. Ye S., Weng Y., Sun S., et al. Comparison of the durations of mild therapeutic hypothermia on outcome after cardiopulmonary resuscitation in the rat. Circulation 2012, 3:123-129.
15. Chenoune M., Lidouren F., Adam C., et al. Ultrafast and whole-body cooling with total liquid ventilation induces favorable neurological and cardiac outcomes after cardiac arrest in rabbits. Circulation 2011, 23:901-911.
16. Yang X., Liu Y., Yang X.M., et al. Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity. Basic Res Cardiol 2011, 106:421-430.
17. Drescher C., Diestel A., Wollersheim S., Berger F., Schmitt K.R. How does hypothermia protect cardiomyocytes during cardioplegic ischemia?. Eur J Cardiothorac Surg 2011, 40:352-359.
18. Caputo M., Ascione R., Angelini G.D., Suleiman M.S., Bryan A.J. The end of the cold era: from intermittent cold to intermittent warm blood cardioplegia. Eur J Cardiothorac Surg 1998, 14:467-475.
19. Borlongan C.V., Wang Y., Su T.P. Delta opioid peptide (d-Ala 2, d-Leu 5) enkephalin: linking hibernation and neuroprotection. Front Biosci 2004, 9:3392-3398.
20. Gross E.R., Gross G.J. Ligand triggers of classical preconditioning and postconditioning. Cardiovasc Res 2006, 70:212-221.
21. Ikeda Y., Miura T., Sakamoto J., et al. Activation of ERK and suppression of calcineurin are interacting mechanisms of cardioprotection afforded by delta-opioid receptor activation. Basic Res Cardiol 2006, 101:418-426.
22. Feng Y., He X., Yang Y., Chao D., Lazarus L.H., Xia Y. Current research on opioid receptor function. Curr Drug Targets 2012, 13:230-246.
23. Chung S.P., Song F.Q., Yu T., et al. Effect of therapeutic hypothermia vs δ-opioid receptor agonist on post resuscitation myocardial function in a rat model of CPR. Resuscitation 2011, 82:350-354.
24. Gazmuri R.J., Weil M.H., Bisera J., Tang W., Fukui M., McKee D. Myocardial dysfunction after successful resuscitation from cardiac arrest. Crit Care Med 1996, 24:992-1000.
25. Hausenloy D.J., Yellon D.M. Survival kinases in ischemic preconditioning and postconditioning. Cardiovasc Res 2006, 70:240-253.
26. Matsui T., Tao J., del Monte F., et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 2001, 104:330-335.
27. Yang X.M., Krieg T., Cui L., et al. NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO. J Mol Cell Cardiol 2004, 36:411-421.
28. Chien S., Oeltgen P.R., Diana J.N., et al. Extension of tissue survival time in multiorgan block preparation with a delta opioid DADLE ([d-Ala2, d-Leu5]-enkephalin). J Thorac Cardiovasc Surg 1994, 107:964-967.
29. Yang X.M., Krieg T., Cui L., Downey J.M., Cohen M.V. In vitro stability and in vivo pharmacokinetic studies of a model opioid peptide. H-Tyr-d-Ala-Gly-Phe-d-Leu-OH (DADLE), and its cyclic prodrugs. J Pharmacol Exp Ther 2002, 303:840-848.
30. Aitchison K.A., Baxter G.F., Awan M.M., Smith R.M., Yellon D.M., Opie L.H. Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: implications for ischemic preconditioning. Basic Res Cardiol 2000, 95:1-10.