Cardiac and neurological assessment of normothermia/warm blood cardioplegia vs hypothermia/cold crystalloid cardioplegia in pediatric cardiac surgery: Insight from a prospective randomized trial

European Journal of Cardio-thoracic Surgery

Volumn 40, Issue 6, 2011, Pages 1384-1390

  Poncelet, Alain J ^a   van Steenberghe, Mathieu ^a   Moniotte, Stéphane ^a   Detaille, Thierry ^a   Beauloye, Christophe ^b   Bertrand, Luc ^b   Nassogne, Marie Cécile ^a   Rubay, Jean E ^a  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Congenital heart disease (CHD); Myocardial metabolism; Myocardial protection cardioplegia; Neurocognitive deficits

Indexed keywords

ADENOSINE TRIPHOSPHATE;

ARTICLE; BODY TEMPERATURE; BRAIN PROTECTION; CARDIOPLEGIA; CLINICAL ARTICLE; COLD CRYSTALLOID CARDIOPLEGIA; HEART MUSCLE CELL; HEART MUSCLE METABOLISM; HEART PROTECTION; HEART SURGERY; HUMAN; HUMAN TISSUE; INDUCED HYPOTHERMIA; INFANT; INTERMITTENT WARM BLOOD CARDIOPLEGIA; NEUROPHYSIOLOGY; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PSYCHOMETRY; RANDOMIZED CONTROLLED TRIAL;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKERS; CARDIOPLEGIC SOLUTIONS; CARDIOPULMONARY BYPASS; CHILD, PRESCHOOL; DEVELOPMENTAL DISABILITIES; EPIDEMIOLOGIC METHODS; HEART ARREST, INDUCED; HEART DEFECTS, CONGENITAL; HUMANS; HYPOTHERMIA, INDUCED; INFANT; INTELLIGENCE; ISOTONIC SOLUTIONS; MYOCARDIAL REPERFUSION INJURY; NEUROPSYCHOLOGICAL TESTS; POSTOPERATIVE COMPLICATIONS; PSYCHOMETRICS;

EID: 82655162213     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1016/j.ejcts.2011.03.047     Document Type: Article

References (25)

1. Hanley F.L. Religion, politics...deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg 2005, 130:1236.
2. Jonas R.A. Normothermic cardiopulmonary bypass in pediatric surgery - reply. J Thorac Cardiovasc Surg 2002, 123:194.
3. Martin D.R., Scott D.F., Downes G.L., Belzer F.O. Primary cause of unsuccessful liver and heart preservation: cold sensitivity of the ATPase system. Ann Surg 1972, 175:111-117.
4. McMurchie E.J., Raison J.K., Cairncross K.D. Temperature-induced phase changes in membranes of heart: a contrast between the thermal response of poikilotherms and homeotherms. Comp Biochem Physiol B 1973, 44:1017-1026.
5. Fuhrman G.J., Fuhrman F.A. Utilization of glucose by the hypothermic rat. Am J Physiol 1963, 205:181-183.
6. Lyons J.M., Raison J.K. A temperature-induced transition in mitochondrial oxidation: contrast between cold and warm-blooded animals. Comp Biochem Physiol 1970, 37:405-411.
7. Magovern G.J., Flaherty J.T., Gott V.L., Bulkley B.H., Gardner T.J. Failure of blood cardioplegia to protect myocardium at lower temperatures. Circulation 1982, 66:I60-I67.
8. Macknight A.D., Leaf A. Regulation of cellular volume. Physiol Rev 1977, 57:510-573.
9. Durandy Y., Hulin S., Lecompte Y. Normothermic cardiopulmonary bypass in pediatric surgery. J Thorac Cardiovasc Surg 2002, 123:194.
10. Durandy Y., Hulin S. Intermittent warm blood cardioplegia in the surgical treatment of congenital heart disease: clinical experience with 1400 cases. J Thorac Cardiovasc Surg 2007, 133:241-246.
11. Cunningham J.N., Adams P.X., Knopp E.A., Baumann F.G., Snively S.L., Gross R.I., Nathan I.M., Spencer F.C. Preservation of ATP, ultrastructure, and ventricular function after aortic cross-clamping and reperfusion. Clinical use of blood potassium cardioplegia. J Thorac Cardiovasc Surg 1979, 78:708-720.
12. Hammon J.W., Graham T.P., Boucek R.J., Parrish M.D., Merrill W.H., Bender H.W. Myocardial adenosine triphosphate content as a measure of metabolic and functional myocardial protection in children undergoing cardiac operation. Ann Thorac Surg 1987, 44:467-470.
13. Lahorra J.A., Torchiana D.F., Tolis G., Bashour C.A., Hahn C., Titus J.S., Geffin G.A., Daggett W.M. Rapid cooling contracture with cold cardioplegia. Ann Thorac Surg 1997, 63:1353-1360.
14. Pouard P., Mauriat P., Ek F., Haydar A., Gioanni S., Laquay N., Vaccaroni L., Vouhe P.R. Normothermic cardiopulmonary bypass and myocardial cardioplegic protection for neonatal arterial switch operation. Eur J Cardiothorac Surg 2006, 30:695-699.
15. Modi P., Suleiman M.S., Reeves B., Pawade A., Parry A.J., Angelini G.D., Caputo M. Myocardial metabolic changes during pediatric cardiac surgery: a randomized study of 3 cardioplegic techniques. J Thorac Cardiovasc Surg 2004, 128:67-75.
16. Ellis R.J., Gardner C. Determination of myocardial high-energy phosphates using bioluminescence. Anal Biochem 1980, 105:354-360.
17. Melrose D.G., Dieger D.B., Bentall H.H., Baker J.B.E. Elective cardiac arrest: preliminary communications. Lancet 1955, 2:21-22.
18. Catinella F.P., Cunningham J.N., Spencer F.C. Myocardial protection during prolonged aortic cross-clamping. Comparison of blood and crystalloid cardioplegia. J Thorac Cardiovasc Surg 1984, 88:411-423.
19. Jacquet L.M., Noirhomme P.H., Van Dyck M.J., El Khoury G.A., Matta A.J., Goenen M.J., Dion R.A. Randomized trial of intermittent antegrade warm blood versus cold crystalloid cardioplegia. Ann Thorac Surg 1999, 67:471-477.
20. Imura H., Modi P., Pawade A., Parry A.J., Suleiman M.S., Angelini G.D., Caputo M. Cardiac troponin I in neonates undergoing the arterial switch operation. Ann Thorac Surg 2002, 74:1998-2002.
21. Siaplaouras J., Thul J., Will J.C., Bauer J., Kreuder J., Valeske K., Akinturk H., Schranz D. [Cardiac troponin I after heart surgery corrective operation in infancy and childhood]. Z Kardiol 2001, 90:408-413.
22. Hillier S.C., Burrows F.A., Bissonnette B., Taylor R.H. Cerebral hemodynamics in neonates and infants undergoing cardiopulmonary bypass and profound hypothermic circulatory arrest: assessment by transcranial Doppler sonography. Anesth Analg 1991, 72:723-728.
23. Cook D.J., Orszulak T.A., Daly R.C., Buda D.A. Cerebral hyperthermia during cardiopulmonary bypass in adults. J Thorac Cardiovasc Surg 1996, 111:268-269.
24. Randomised trial of normothermic versus hypothermic coronary bypass surgery. The Warm Heart Investigators. Lancet 1994;343:559-63.
25. Rasmussen L.S., Sztuk F., Christiansen M., Elliott M.J. Normothermic versus hypothermic cardiopulmonary bypass during repair of congenital heart disease. J Cardiothorac Vasc Anesth 2001, 15:563-566.