Validation of a rat model of cardiopulmonary bypass with a new miniaturized hollow fiber oxygenator

ASAIO Journal

Volumn 54, Issue 5, 2008, Pages 514-518

  Cresce, Giovanni Domenico ^a   Walpoth, Beat H ^c   Mugnai, Damiano ^c   Innocente, Francesco ^a   Rungatscher, Alessio ^a   Luciani, Giovanni Battista ^a   Zaniboni, Andrea ^b   Battistuzzi, Gabriele ^b   Tessari, Maddalena ^a   Kalangos, Afksendiyos ^c   Mazzucco, Alessandro ^a   Faggian, Giuseppe ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b Cyberonics Inc   (Italy)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BEFORE AND AFTER; BLOOD FLOW RATE; BLOOD OXYGENATION; CARDIAC SURGERY; CARDIOPULMONARY BYPASS; CAROTID ARTERY; CPB CIRCUITS; ESSENTIAL COMPONENT; GAS EXCHANGE; GAS TRANSFER; HEART SURGERY; HEAT EXCHANGE SURFACES; HOLLOW FIBER; IN-VITRO; IN-VIVO; RAT MODEL; ROLLER PUMPS; ROOM AIR; SMALL ANIMAL; SMALL VARIATIONS; SUPERIOR VENA CAVA;

BLOOD; BREAKWATERS; FLOW RATE; HEMODYNAMICS; HYDRODYNAMICS; OXYGENATION; SPECIFICATIONS; SURGERY;

OXYGENATORS;

OXYGEN;

AIR CONDITIONING; AMBIENT AIR; ANESTHESIA; ANIMAL MODEL; AORTA; BLOOD FLOW VELOCITY; BLOOD OXYGENATION; CANNULATION; CARBON DIOXIDE TENSION; CARDIOPULMONARY BYPASS; CAROTID ARTERY; CAVA VEIN; CENTRAL VEIN; CONFERENCE PAPER; GAS EXCHANGE; HEART SURGERY; HEMODYNAMICS; HOLLOW FIBER; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; ITALY; MALE; NONHUMAN; OXYGEN TENSION; OXYGENATOR; PHARMACODYNAMICS; PRESSURE MEASUREMENT; PUMP; RAT; VALIDATION STUDY; ANIMAL; ARTICLE; ELECTRONICS; EXTRACORPOREAL OXYGENATION; INSTRUMENTATION; METHODOLOGY; REPRODUCIBILITY; WISTAR RAT;

ANIMALS; CARDIOPULMONARY BYPASS; EXTRACORPOREAL MEMBRANE OXYGENATION; MALE; MINIATURIZATION; MODELS, ANIMAL; OXYGENATORS, MEMBRANE; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS;

EID: 55949106717     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAT.0b013e3181877a38     Document Type: Conference Paper

References (20)

1. Nolan SP, Zacour R, Dammann JF: Reflections on the evolution of cardiopulmonary bypass. Ann Thorac Surg 64: 1540-1543, 1997.
2. Palanzo DA: Perfusion safety: Past, present, and future. J Cardiothorac Vasc Anaesth 11: 383-390, 1997.
3. Kirklin JK, Westaby S, Backstone EH, et al: Complement and the damaging effects of cardiopulmonary bypass. J Thorac Cardiovasc Surg 86: 845-857, 1983.
4. Westaby S: Organ dysfunction after cardiopulmonary bypass. A systemic inflammatory reaction initiated by the extracorporeal circuit. Intensive Care Med 13: 89-95, 1987.
5. Levy JH, Tanaka KA: Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg 75: S715-S720, 2003.
6. Paparella D, Yau TM, Young E: Cardiopulmonary bypass induced inflammation: Pathophysiology and treatment. An update. Eur J Cardiothorac Surg 21: 232-244, 2002.
7. Podgoreanu MV, Michelotti GA, Sato Y, et al: Differential cardiac gene expression during cardiopulmonary bypass: Ischemia-independent upregulation of proinflammatory genes. J Thorac Cardiovasc Surg 130: 330-339, 2005.
8. Hiramatsu Y, Gikakis N, Gorman JH III, et al: A baboon model for hematologic studies of cardiopulmonary bypass. J Lab Clin Med 130: 412-420, 1997.
9. Kim WG, Moon HJ, Won TH, Chee HK: Rabbit model of cardiopulmonary bypass. Perfusion 14: 101-105, 1999.
10. Wittnich C, Belanger MP, Wallen WJ, et al: A long-term stable normothermic cardiopulmonary bypass model in neonatal swine. J Surg Res 1001: 176-182, 2001.
11. Sasaki S, Takigami K, Shiiya N, Yasuda K: Partial cardiopulmonary bypass in rats for evaluating ischemia-reperfusion injury. ASAIO J 42: 1027-1030, 1996.
12. Sack FU, Dollner R, Reidenbach B, et al: Extracorporeal circulation induced microvascular perfusion injury of the small bowel. Eur Surg Res 34: 418-424, 2002.
13. Ballaux PK, Gourlay T, Ratnatunga CP, Taylor KM: A literature review of cardiopulmonary bypass models for rats. Perfusion 14: 411-415, 1999.
14. Fabre O, Zegdi R, Vicentinelli A, et al: A recovery model of partial cardiopulmonary bypass in the rat. Perfusion 16: 215-218, 2001.
15. Günzinger R, Wildhirt SM, Schad H, et al: A rat model of cardiopulmonary bypass with cardioplegic arrest and hemodynamic assessment by conductance catheter technique. Basic Res Car-diol 102: 508-517, 2007.
16. Dong GH, Xu B, Wang CT, et al: A rat model of cardiopulmonary bypass with excellent survival. J Surg Res 123: 171-175, 2005.
17. Alexander B, Al Ani H: Prolonged partial cardiopulmonary bypass in the rats. J Surg Res 35: 28-34, 1983.
18. Grocott HP, Mackensen GB, Newman MF, Warner DS: Neurological injury during cardiopulmonary bypass in the rat. Perfusion 16: 75-81, 2001.
19. Gourlay T, Ballaux PK, Draper ER, Taylor KM: Early experience with a new technique and technology designed for the study of pulsatile cardiopulmonary bypass in the rat. Perfusion 17: 191-198, 2002.
20. Jungwirth B, Mackensen GB, Blobner M, et al: Neurologic outcome after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats. Description of a new model. J Thorac Cardiovasc Surg 131: 805-812, 2006.