-
1
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
M.M. Gottesman, and I. Pastan Biochemistry of multidrug resistance mediated by the multidrug transporter Annu. Rev. Biochem. 62 1993 385 427
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
2
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
R.L. Juliano, and V. Ling A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants Biochim. Biophys. Acta 455 1976 152 162
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
3
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
A. Sparreboom, J. van Asperen, U. Mayer, A.H. Schinkel, J.W. Smit, D.K. Meijer, P. Borst, W.J. Nooijen, J.H. Beijnen, and O. van Tellingen Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine Proc. Natl. Acad. Sci. U. S. A. 94 1997 2031 2035
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
Van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
-
4
-
-
0008632564
-
Expression of a full-length cDNA for the human "mDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
-
K. Ueda, C. Cardarelli, M.M. Gottesman, and I. Pastan Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine Proc. Natl. Acad. Sci. U. S. A. 84 1987 3004 3008
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 3004-3008
-
-
Ueda, K.1
Cardarelli, C.2
Gottesman, M.M.3
Pastan, I.4
-
5
-
-
0022972654
-
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
-
C. Chen, J.E. Chin, K. Ueda, D.P. Clark, I. Pastan, M.M. Gottesman, and I.B. Roninson Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells Cell 47 1986 381 389
-
(1986)
Cell
, vol.47
, pp. 381-389
-
-
Chen, C.1
Chin, J.E.2
Ueda, K.3
Clark, D.P.4
Pastan, I.5
Gottesman, M.M.6
Roninson, I.B.7
-
6
-
-
0032516734
-
Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein
-
Y. Takada, K. Yamada, Y. Taguchi, K. Kino, M. Matsuo, S.J. Tucker, T. Komano, T. Amachi, and K. Ueda Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein Biochim. Biophys. Acta 1373 1998 131 136
-
(1998)
Biochim. Biophys. Acta
, vol.1373
, pp. 131-136
-
-
Takada, Y.1
Yamada, K.2
Taguchi, Y.3
Kino, K.4
Matsuo, M.5
Tucker, S.J.6
Komano, T.7
Amachi, T.8
Ueda, K.9
-
7
-
-
0028786395
-
Both P-glycoprotein nucleotide-binding sites are catalytically active
-
I.L. Urbatsch, B. Sankaran, S. Bhagat, and A.E. Senior Both P-glycoprotein nucleotide-binding sites are catalytically active J. Biol. Chem. 270 1995 26956 26961
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26956-26961
-
-
Urbatsch, I.L.1
Sankaran, B.2
Bhagat, S.3
Senior, A.E.4
-
9
-
-
0026068740
-
Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes
-
E. Buschman, and P. Gros Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes Mol. Cell. Biol. 11 1991 595 603
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 595-603
-
-
Buschman, E.1
Gros, P.2
-
10
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
J.J. Smit, A.H. Schinkel, R.P. Oude Elferink, A.K. Groen, E. Wagenaar, L. van Deemter, C.A. Mol, R. Ottenhoff, N.M. van der Lugt, M.A. van Roon, M.A. van der Valk, G.J.A. Offerhaus, A.J.M. Berns, and P. Borst Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease Cell 75 1993 451 462
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.1
Schinkel, A.H.2
Oude Elferink, R.P.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Ottenhoff, R.8
Van Der Lugt, N.M.9
Van Roon, M.A.10
Van Der Valk, M.A.11
Offerhaus, G.J.A.12
Berns, A.J.M.13
Borst, P.14
-
11
-
-
34547400136
-
Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4
-
S.Y. Morita, A. Kobayashi, Y. Takanezawa, N. Kioka, T. Handa, H. Arai, M. Matsuo, and K. Ueda Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4 Hepatology 46 2007 188 199
-
(2007)
Hepatology
, vol.46
, pp. 188-199
-
-
Morita, S.Y.1
Kobayashi, A.2
Takanezawa, Y.3
Kioka, N.4
Handa, T.5
Arai, H.6
Matsuo, M.7
Ueda, K.8
-
12
-
-
0030577373
-
Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins
-
K. Kino, Y. Taguchi, K. Yamada, T. Komano, and K. Ueda Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins FEBS Lett. 399 1996 29 32
-
(1996)
FEBS Lett.
, vol.399
, pp. 29-32
-
-
Kino, K.1
Taguchi, Y.2
Yamada, K.3
Komano, T.4
Ueda, K.5
-
13
-
-
0034604707
-
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
-
A.J. Smith, A. van Helvoort, G. van Meer, K. Szabo, E. Welker, G. Szakacs, A. Varadi, B. Sarkadi, and P. Borst MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping J. Biol. Chem. 275 2000 23530 23539
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23530-23539
-
-
Smith, A.J.1
Van Helvoort, A.2
Van Meer, G.3
Szabo, K.4
Welker, E.5
Szakacs, G.6
Varadi, A.7
Sarkadi, B.8
Borst, P.9
-
14
-
-
0007544439
-
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
-
A. van Helvoort, A.J. Smith, H. Sprong, I. Fritzsche, A.H. Schinkel, P. Borst, and G. van Meer MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine Cell 87 1996 507 517
-
(1996)
Cell
, vol.87
, pp. 507-517
-
-
Van Helvoort, A.1
Smith, A.J.2
Sprong, H.3
Fritzsche, I.4
Schinkel, A.H.5
Borst, P.6
Van Meer, G.7
-
16
-
-
0030858837
-
Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human mDR1/P-glycoprotein
-
Y. Taguchi, K. Kino, M. Morishima, T. Komano, S.E. Kane, and K. Ueda Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human mDR1/P-glycoprotein Biochemistry 36 1997 8883 8889
-
(1997)
Biochemistry
, vol.36
, pp. 8883-8889
-
-
Taguchi, Y.1
Kino, K.2
Morishima, M.3
Komano, T.4
Kane, S.E.5
Ueda, K.6
-
17
-
-
0030611865
-
MgADP antagonism to Mg-independent ATP binding of the sulfonylurea receptor SUR1
-
K. Ueda, N. Inagaki, and S. Seino MgADP antagonism to Mg-independent ATP binding of the sulfonylurea receptor SUR1 J. Biol. Chem. 272 1997 22983 22986
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22983-22986
-
-
Ueda, K.1
Inagaki, N.2
Seino, S.3
-
18
-
-
10744227683
-
Microanalysis for MDR1 ATPase by high-performance liquid chromatography with a titanium dioxide column
-
Y. Kimura, S. Shibasaki, K. Morisato, N. Ishizuka, H. Minakuchi, K. Nakanishi, M. Matsuo, T. Amachi, M. Ueda, and K. Ueda Microanalysis for MDR1 ATPase by high-performance liquid chromatography with a titanium dioxide column Anal. Biochem. 326 2004 262 266
-
(2004)
Anal. Biochem.
, vol.326
, pp. 262-266
-
-
Kimura, Y.1
Shibasaki, S.2
Morisato, K.3
Ishizuka, N.4
Minakuchi, H.5
Nakanishi, K.6
Matsuo, M.7
Amachi, T.8
Ueda, M.9
Ueda, K.10
-
19
-
-
67650498383
-
Functional role of the linker region in purified human P-glycoprotein
-
T. Sato, A. Kodan, Y. Kimura, K. Ueda, T. Nakatsu, and H. Kato Functional role of the linker region in purified human P-glycoprotein FEBS J. 276 2009 3504 3516
-
(2009)
FEBS J.
, vol.276
, pp. 3504-3516
-
-
Sato, T.1
Kodan, A.2
Kimura, Y.3
Ueda, K.4
Nakatsu, T.5
Kato, H.6
-
21
-
-
0029124166
-
P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site
-
I.L. Urbatsch, B. Sankaran, J. Weber, and A.E. Senior P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site J. Biol. Chem. 270 1995 19383 19390
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19383-19390
-
-
Urbatsch, I.L.1
Sankaran, B.2
Weber, J.3
Senior, A.E.4
-
22
-
-
34547734539
-
Mechanism of multidrug recognition by MDR1/ABCB1
-
Y. Kimura, S.Y. Morita, M. Matsuo, and K. Ueda Mechanism of multidrug recognition by MDR1/ABCB1 Cancer Sci. 98 2007 1303 1310
-
(2007)
Cancer Sci.
, vol.98
, pp. 1303-1310
-
-
Kimura, Y.1
Morita, S.Y.2
Matsuo, M.3
Ueda, K.4
-
23
-
-
0027432409
-
Fluorescent cellular indicators are extruded by the multidrug resistance protein
-
L. Homolya, Z. Hollo, U.A. Germann, I. Pastan, M.M. Gottesman, and B. Sarkadi Fluorescent cellular indicators are extruded by the multidrug resistance protein J. Biol. Chem. 268 1993 21493 21496
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21493-21496
-
-
Homolya, L.1
Hollo, Z.2
Germann, U.A.3
Pastan, I.4
Gottesman, M.M.5
Sarkadi, B.6
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