EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 6, 2013, Pages 2088-2093

  Ruszczycky, Mark W ^a   Choi, Sei Hyun ^a   Liu, Hung Wen ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

AdoMet; Catalytic comMitment; Desosamine; Enzymology; Solvent isotope effect

Indexed keywords

ALCOHOL DEHYDROGENASE; DESII ENZYME; DEUTERIUM; ISOTOPE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DEHYDROGENATION; ELECTRON SPIN RESONANCE; ENZYME ANALYSIS; PRIORITY JOURNAL; PROTON TRANSPORT; STEADY STATE; STREPTOMYCES VENEZUELAE;

ALCOHOLS; DEUTERIUM; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HYDROGEN-ION CONCENTRATION; KINETICS; OXIDOREDUCTASES; S-ADENOSYLMETHIONINE; SOLVENTS; STREPTOMYCES;

EID: 84873458694     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1209446110     Document Type: Article

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