Methyl jasmonate abolishes the migration, invasion and angiogenesis of gastric cancer cells through down-regulation of matrix metalloproteinase 14

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Zheng, Liduan ^a   Li, Dan ^a   Xiang, Xuan ^a   Tong, Ling ^a   Qi, Meng ^a   Pu, Jiarui ^a   Huang, Kai ^a   Tong, Qiangsong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Gastric cancer; Matrix metalloproteinase 14; Methyl jasmonate; Specificity protein 1

Indexed keywords

JASMONIC ACID METHYL ESTER; MATRIX METALLOPROTEINASE 14; TRANSCRIPTION FACTOR SP1;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN MKN 45; CELL STRAIN SGC 7901; CELL VIABILITY; CLINICAL ARTICLE; COLORIMETRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CANCER; WESTERN BLOTTING;

ACETATES; ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING SITES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 14; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; OXYLIPINS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR; STOMACH NEOPLASMS; TIME FACTORS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84873447008     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-74     Document Type: Article

References (46)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011, 61:69-90. 10.3322/caac.20107, 21296855.
2. Terry MB, Gaudet MM, Gammon MD. The epidemiology of gastric cancer. Semin Radiat Oncol 2002, 12:111-127. 10.1053/srao.30814, 11979413.
3. Oba K, Burzykowski T, Michiels S, Ohashi Y, Pignon JP, Rougier P, Sakamoto J, Sargent D, Sasako M, Van Cutsem E, Buyse M, GASTRIC (Global Advanced/Adjuvant Stomach Tumor Research International Collaboration) Group PX Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis. JAMA 2010, 303:1729-1737. GASTRIC (Global Advanced/Adjuvant Stomach Tumor Research International Collaboration) Group PX.
4. Cragg GM, Newman DJ. Plants as a source of anti-cancer and anti-HIV agents. Ann Appl Biol 2003, 143:127-133.
5. Cragg GM, Newman DJ. Plants as a source of anti-cancer agents. J Ethnopharmacol 2005, 100:72-79. 10.1016/j.jep.2005.05.011, 16009521.
6. Fingrut O, Flescher E. Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells. Leukemia 2002, 16:608-616. 10.1038/sj.leu.2402419, 11960340.
7. Ordan O, Rotem R, Jaspers I, Flescher E. Stress-responsive JNK mitogen-activated protein kinase mediates aspirin-induced suppression of B16 melanoma cellular proliferation. Br J Pharmacol 2003, 138:1156-1162. 10.1038/sj.bjp.0705163, 1573760, 12684272.
8. Sembdner G, Parthier B. The biochemistry and the physiological and molecular actions of jasmonates. Annu Rev Plant Physiol Plant Mol Biol 1993, 44:569-589.
9. Cohen S, Flescher E. Methyl jasmonate: A plant stress hormone as an anti-cancer drug. Phytochemistry 2009, 70:1600-1609. 10.1016/j.phytochem.2009.06.007, 19660769.
10. Flescher E. Jasmonates in cancer therapy. Cancer Lett 2007, 245:1-10. 10.1016/j.canlet.2006.03.001, 16600475.
11. Rotem R, Heyfets A, Fingrut O, Blickstein D, Shaklai M, Flescher E. Jasmonates: novel anticancer agents acting directly and selectively on human cancer cell mitochondria. Cancer Res 2005, 65:1984-1993. 10.1158/0008-5472.CAN-04-3091, 15753398.
12. Tong Q, Jiang G, Zheng L, Tang S, Cai J, Liu Y, Zeng F, Dong J. Natural jasmonates of different structures suppress the growth of human neuroblastoma cell line SH-SY5Y and its mechanisms. Acta Pharmacol Sin 2008, 29:861-869. 10.1111/j.1745-7254.2008.00814.x, 18565287.
13. Tong Q, Jiang G, Zheng L, Tang S, Cai J, Liu Y, Zeng F, Dong J. Methyl jasmonate downregulates expression of proliferating cell nuclear antigen and induces apoptosis in human neuroblastoma cell lines. Anti-Cancer Drugs 2008, 19:573-581. 10.1097/CAD.0b013e3282fc46b0, 18525316.
14. Jiang G, Zhao J, Xiao X, Tao D, Gu C, Tong Q, Luo B, Wang L, Zeng F. AN N-terminal Smac peptide sensitizes human prostate carcinoma cells to methyl jasmonate-induced apoptosis. Cancer Lett 2011, 302:37-46. 10.1016/j.canlet.2010.12.009, 21237556.
15. Zheng L, Jiang G, Mei H, Pu J, Dong J, Hou X, Tong Q. Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells. BMC Cancer 2010, 10:33. 10.1186/1471-2407-10-33, 2834619, 20137078.
16. Zhang H, Qi M, Li S, Qi T, Mei H, Huang K, Zheng L, Tong Q. microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. Mol Cancer Ther 2012, 11:1454-1466. 10.1158/1535-7163.MCT-12-0001, 22564723.
17. Valster A, Tran NL, Nakada M, Berens ME, Chan AY, Symons M. Cell migration and invasion assays. Methods 2005, 37:208-215. 10.1016/j.ymeth.2005.08.001, 16288884.
18. Nicosia RF, Ottinetti A. Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro. Lab Invest 1990, 63:115-122.
19. Jiang G, Zheng L, Pu J, Mei H, Zhao J, Huang K, Zeng F, Tong Q. Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cells. PLoS One 2012, 7:e31379. 10.1371/journal.pone.0031379, 3282686, 22363633.
20. Sroka IC, Nagle RB, Bowden GT. Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells. Neoplasia 2007, 9:406-417. 10.1593/neo.07193, 1877982, 17534446.
21. Reischer D, Heyfets A, Shimony S, Nordenberg J, Kashman Y, Flescher E. Effects of natural and novel synthetic jasmonates in experimental metastatic melanoma. Br J Pharmacol 2007, 150:738-749. 10.1038/sj.bjp.0707146, 2013862, 17293888.
22. Pereira Lopes J, Barbosa M, Stella C, Santos W, Pereira E, Nogueira-Neto J, Augusto E, Silva L, Smaili S, Gomes L. In vivo anti-angiogenic effects further support the promise of the antineoplasic activity of methyl jasmonate. Braz J Biol 2010, 70:443-449. 10.1590/S1519-69842010000200029, 20549071.
23. Zhang M, Zhu GY, Gao HY, Zhao SP, Xue Y. Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma. J Surg Oncol 2011, 103:243-247. 10.1002/jso.21824, 21337552.
24. Sounni NE, Devy L, Hajitou A, Frankenne F, Munaut C, Gilles C, Deroanne C, Thompson EW, Foidart JM, Noel A. MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression. FASEB J 2002, 16:555-564. 10.1096/fj.01-0790com, 11919158.
25. Hoeben A, Landuyt B, Highley MS, Wildiers H, Van Oosterom AT, De Bruijn EA. Vascular endothelial growth factor and angiogenesis. Pharmacol Rev 2004, 56:549-580. 10.1124/pr.56.4.3, 15602010.
26. Yeruva L, Pierre KJ, Carper SW, Elegbede JA, Toy BJ, Wang RC. Jasmonates induce apoptosis and cell cycle arrest in non-small cell lung cancer lines. Exp Lung Res 2006, 32:499-516. 10.1080/01902140601059604, 17169856.
27. Raviv Z, Zilberberg A, Cohen S, Reischer-Pelech D, Horrix C, Berger MR, Rosin-Arbesfeld R, Flescher E. Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity. Br J Pharmacol 2011, 164:1433-1444. 10.1111/j.1476-5381.2011.01419.x, 3221098, 21486277.
28. Oh SYKJ, Park MJ, Kim SM, Yoon CS, Joo YM, Park JS, Han SI, Park HG, Kang HS. Induction of heat shock protein 72 in C6 glioma cells by methyl jasmonate through ROS-dependent heat shock factor 1 activation. Int J Mol Med 2005, 16:833-839.
29. Milrot E, Jackman A, Kniazhanski T, Gonen P, Flescher E, Sherman L. Methyl jasmonate reduces the survival of cervical cancer cells and downregulates HPV E6 and E7, and survivin. Cancer Lett 2012, 319:31-38. 10.1016/j.canlet.2011.12.028, 22198483.
30. Kniazhanski T, Jackman A, Heyfets A, Gonen P, Flescher E, Sherman L. Methyl jasmonate induces cell death with mixed characteristics of apoptosis and necrosis in cervical cancer cells. Cancer Lett 2008, 271:34-46. 10.1016/j.canlet.2008.05.031, 18599197.
31. Ishii Y, Kiyota H, Sakai S, Honma Y. Induction of differentiation of human myeloid leukemia cells by jasmonates, plant hormones. Leukemia 2004, 18:1413-1419. 10.1038/sj.leu.2403421, 15229618.
32. Tsumura H, Akimoto M, Kiyota H, Ishii Y, Ishikura H, Honma Y. Gene expression profiles in differentiating leukemia cells induced by methyl jasmonate are similar to those of cytokinins and methyl jasmonate analogs induce the differentiation of human leukemia cells in primary culture. Leukemia 2008, 23:753-760.
33. Fingrut O, Reischer D, Rotem R, Goldin N, Altboum I, Zan-Bar I, Flescher E. Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells. Br J Pharmacol 2005, 146:800-808. 10.1038/sj.bjp.0706394, 1751213, 16170329.
34. Kim JHLS, Oh SY, Han SI, Park HG, Yoo MA, Kang HS. Methyl jasmonate induces apoptosis through induction of Bax/Bcl-XS and activation of caspase-3 via ROS production in A549 cells. Oncol Rep 2004, 12:1233.
35. Yeruva L, Elegbede JA, Carper SW. Methyl jasmonate decreases membrane fluidity and induces apoptosis through tumor necrosis factor receptor 1 in breast cancer cells. Anti-Cancer Drugs 2008, 19:766-776. 10.1097/CAD.0b013e32830b5894, 2745996, 18690087.
36. Lin CH, Fu ZM, Liu YL, Yang JL, Xu JF, Chen QS, Chen HM. Investigation of SGC-7901 cell line established from human gastric carcinoma cells. Chin Med J 1984, 97:831-834.
37. Motoyama T, Hojo H, Watanabe H. Comparison of seven cell lines derived from human gastric carcinomas. Acta Pathol Jpn 1986, 36:65-83.
38. Liotta LA, Stetler-Stevenson WG. Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res 1991, 51:5054s-5059s.
39. Kaneko T, Konno H, Baba M, Tanaka T, Nakamura S. Urokinase-type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer. Cancer Sci 2003, 94:43-49. 10.1111/j.1349-7006.2003.tb01350.x, 12708473.
40. Chun T-H, Sabeh F, Ota I, Murphy H, McDonagh KT, Holmbeck K, Birkedal-Hansen H, Allen ED, Weiss SJ. MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix. J Cell Biol 2004, 167:757-767. 10.1083/jcb.200405001, 2172577, 15545316.
41. Aplin AC, Zhu WH, Fogel E, Nicosia RF. Vascular regression and survival are differentially regulated by MT1-MMP and TIMPs in the aortic ring model of angiogenesis. Am J Physiol Cell Physiol 2009, 297:C471-C480. 10.1152/ajpcell.00019.2009, 2724089, 19494241.
42. Sabeh F, Ota I, Holmbeck K, Birkedal-Hansen H, Soloway P, Balbin M, Lopez-Otin C, Shapiro S, Inada M, Krane S, Allen E, Chung D, Weiss SJ. Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J Cell Biol 2004, 167:769-781. 10.1083/jcb.200408028, 2172570, 15557125.
43. Jiang WGDG, Martin TA, Parr C, Watkins G, Mason MD, Mansel RE. Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells. Int J Mol Med 2006, 17:583-590.
44. Lohi J, Lehti K, Valtanen H, Parks WC, Keski-Oja J. Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene. Gene 2000, 242:75-86. 10.1016/S0378-1119(99)00549-1, 10721699.
45. Alfonso-Jaume MA, Mahimkar R, Lovett DH. Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells. Biochem J 2004, 380:735-747. 10.1042/BJ20031281, 1224202, 14979875.
46. Dey B, Thukral S, Krishnan S, Chakrobarty M, Gupta S, Manghani C, Rani V. DNA-protein interactions: methods for detection and analysis. Mol Cell Biochem 2012, 365:279-299. 10.1007/s11010-012-1269-z, 22399265.