Functionalized magnetic nanoparticles as vehicles for the delivery of the antitumor drug gemcitabine to tumor cells. Physicochemical in vitro evaluation

Materials Science and Engineering C

Volumn 33, Issue 3, 2013, Pages 1183-1192

  Viota, J L ^a   Carazo, A ^a   Munoz Gamez, J A ^a   Rudzka, K ^b   Gomez Sotomayor R ^b   Ruiz Extremera, A ^a,b   Salmeron J ^a,b   Delgado, A V ^b  

^a HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

Electrophoretic mobility; Gemcitabine; Magnetic nanoparticles; Polyelectrolyte coating; Soft particle; Tumor cell

Indexed keywords

ALTERNATIVE APPROACH; ANTICANCER DRUG; ANTITUMOR DRUGS; BREAST TUMOR CELLS; CARBOPOL; COMPOSITE NANOPARTICLES; COMPOSITE PARTICLES; DRUG DELIVERY SYSTEM; FOLIC ACIDS; FUNCTIONALIZED; GEMCITABINE; HIGH MOLECULAR WEIGHT; IN-VITRO; IN-VITRO EVALUATION; MAGNETIC NANOPARTICLES; OPTICAL ABSORBANCE; POLY(ACRYLIC ACID ); SELF ASSEMBLED NANOSTRUCTURES; SOFT PARTICLES; TUMOR CELLS;

ADSORPTION; BIOCHEMISTRY; CARBOXYLIC ACIDS; CELL MEMBRANES; CHEMOTHERAPY; COMPOSITE MATERIALS; CYTOLOGY; DRUG DELIVERY; ELECTROPHORETIC MOBILITY; MAGNETITE NANOPARTICLES; MOLECULAR WEIGHT; NANOPARTICLES; TUMORS;

DRUG PRODUCTS;

ACRYLIC ACID RESIN; ANTINEOPLASTIC AGENT; CARBOPOL 940; DEOXYCYTIDINE; FOLIC ACID; GEMCITABINE; MAGNETITE NANOPARTICLE; DRUG DERIVATIVE; MAGNETIC NANOPARTICLE;

ADSORPTION; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ELECTROPHORESIS; FLUORESCENCE IMAGING; HUMAN; NEOPLASMS; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; TUMOR CELL LINE; ULTRASTRUCTURE; ARTICLE; DRUG EFFECT; ELECTROPHORETIC MOBILITY; NEOPLASM; POLYELECTROLYTE COATING; SOFT PARTICLE; TUMOR CELL;

ACRYLIC RESINS; ADSORPTION; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DEOXYCYTIDINE; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS; FOLIC ACID; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETITE NANOPARTICLES; MICROSCOPY, CONFOCAL; NEOPLASMS; OPTICAL IMAGING; PARTICLE SIZE; PHYSICOCHEMICAL PHENOMENA;

ELECTROPHORETIC MOBILITY; GEMCITABINE; MAGNETIC NANOPARTICLES; POLYELECTROLYTE COATING; SOFT PARTICLE; TUMOR CELL;

EID: 84873413881     PISSN: 09284931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.msec.2012.12.009     Document Type: Article

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