Recombinant expression of the autocatalytic complement protease MASP-1 is crucially dependent on co-expression with its inhibitor, C1 inhibitor

Protein Expression and Purification

Volumn 88, Issue 2, 2013, Pages 173-182

  Degn, Søren E ^a   Thiel, Steffen ^a   Jensenius, Jens C ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Auto activating enzyme; Complement; Lectin pathway; MASP; Serine protease; Zymogen

Indexed keywords

COMPLEMENT COMPONENT C1S INHIBITOR; ENZYME PRECURSOR; FICOLIN; LECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; MANNOSE BINDING LECTIN; MASP1 PROTEIN, HUMAN; MASP2 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CELL LINE; CELL STRAIN HEPG2; GENE EXPRESSION; GENE VECTOR; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MOLECULAR CLONING; SITE DIRECTED MUTAGENESIS;

ANIMALS; CELL LINE; CLONING, MOLECULAR; COMPLEMENT C1 INACTIVATOR PROTEINS; ENZYME PRECURSORS; GENE EXPRESSION; GENETIC VECTORS; HEP G2 CELLS; HUMANS; LECTINS; MANNOSE-BINDING LECTIN; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS;

EID: 84873388516     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2013.01.002     Document Type: Article

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